Dl-Norepinephrine Hydrochloride DL-去甲肾上腺素盐酸盐

CAS 55-27-6 MFCD00012880

化学结构图

55-27-6
SMILES: Cl.NCC(O)C1=CC(O)=C(O)C=C1

化学属性

Mol. FormulaC8H11NO3.ClH
Mol. Weight205.66
Melting Point140-144 °C (dec.)
Appearance crystalline

别名和识别编码

Chemical NameDl-Norepinephrine Hydrochloride
CAS Number55-27-6
Synonym (±)-Noradrenaline hydrochloride DL-ARTERENOL HYDROCHLORIDE 4-(2-Amino-1-hydroxyethyl)- (+-)-Noradrenaline hydrochloride (+/-)-ARTERENOL HYDROCHLORIDE DL-ARTERENOL 2-AMINO-1-(3,4-DIHYDROXYPHENYL)ETHANOL HYDROCHLORIDE (±)-Norepinephrine (+/-)-1-(3,4-DIHYDR dl-Norepinephrine hydrochloride DL-α-(aminomethyl)-3,4-dihydroxybenzyl alcohol (+-)-Norepinephrine hydrochloride 1,2-Benzenediol, 4-(2-amino-1-hydroxyethyl)-, hydrochloride, (±)- (+/-)-NORADRENALIN HYDROCHLORIDE (±)-Norepinephrinhydrochlorid (±)-Noradrenalinhydrochlorid DL-NOREPINEPHRINE HYDROCHLORIDE 1-[3,4-DIHYDROXYPHENYL]-2-AMINOETHANOL HYDROCHLORIDE 4-(2-amino-1-hydroxyethyl)-,hydrochloride,(+-)-2-benzenediol DL-Arterenol hydrochloride Norepinephrin-hydrochlorid 3,4-Dihydroxyphenyl)-1-amino-2-ethanol-1, hydrochloride DL-NORADRENALIN HYDROCHLORIDE DL-3,4-DIHYDROXYPHENYLETHANOLAMINE-HCL ARTERENOL,(DL) HYDROCHLORIDE dl-Noradrenaline hydrochloride DL-alpha-(Aminomethyl)-3,4-dihydroxybenzyl alcohol (+/-)-NOREPINEPHRINE HYDROCHLORIDE 3,4-DIHYDROXYPHENYLETHANOLAMINE HYDROCHLORIDE Benzyl alcohol, α-(aminomethyl)-3,4-dihydroxy-, hydrochloride-, (±)- 1,2-Benzenediol, 4-(2-amino-1-hydroxyethyl)-, hydrochloride DL-Norepinephrine hydrochloride (+/-)-3,4-DIHYDROXYPHENYLETHANOLAMINE HYDROCHLORIDE (±)-1-(3,4-二羟苯基)-2-氨基乙醇 盐酸盐 (±)-4-(2-氨基-1-羟乙基)-1,2-苯二醇 盐酸盐 DL-动脉醇 盐酸盐 DL DL-NORADRENALINE HYDROCHLORIDE dl-Arterenol hydrochloride 1,2-Benzenediol, 4-(2-amino-1-hydroxyethy
MDL NumberMFCD00012880
Beilstein Registry Number3707003
EC Number200-229-8
PubChem Substance ID24891195
Chemical Name TranslationDL-去甲肾上腺素盐酸盐
Wiswesser Line NotationZ1YQR CQ DQ &GH -R
LabNetwork Molecule IDLN00198652
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分类

  • Aromatics
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • {uni_hamburg} no charge; carbocycle; aromatic; 6RingOnly; 6ring; alcohol; racemate; 2fragments; ionic
  • Amines
  • {SNA} Amino Alcohols, Building Blocks, Chemical Synthesis, Organic Building Blocks, Oxygen Compounds

产品应用

  • Antagonist of dibutyryl cyclic AMP in the regulation of narcosis.

相关文献及参考

  • Piguet, P., et al.: J. Exp. Med., 173, 673 (1991),
  • Short: EINECS Title: EINECS (European Inventory of Existing Commercial Chemical Substances) Source: Official Journal of the European Communities Volume: C 146 A (15.06.1990) Page: 1 Year: 1990 Internet Resource: http://ecb.jrc.ec.europa.eu/esis/index.php?PGM=ein Publish_Date: 1990/06/15
  • Short: III/5a Title: Structure Data of Organic Crystals: C ... C 13 Author: Schudt, E.; Weitz, G. Editor: Hellwege, K.-H.; Hellwege, A.M. Source: Landolt-Börnstein, New Series Volume: III/5a Year: 1971 ISBN: 3-540-05177-5 ISBN: 978-3-540-05177-0 Internet Resource: DOI:10.1007/b19970 RefComment: XXI, 736 pages, and VII, 890 pages. Hardcover Abstract: Volume III/5 offers a compitation as complete as possible of the space groups and lattice con-stants of all crystals which have been studied by means of X-rays, neutron and electron diffraction.
  • [1]. Matsuda H, et al. Effects of nitroglycerin, adenosine, noradrenal

安全信息

RTECSDN6650000
WGK Germany3
GHS Symbol
Hazard statements
  • H301 Toxic if swallowed 吞食有毒
Personal Protective Equipment Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Precautionary statements
  • P301+P310
Signal word Danger
Hazard Codes T
Safety Statements
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
Risk Statements
  • R25 Toxic if swallowed 吞咽有毒
UN Number UN 2811 6.1/PG 3 2811
Packing GroupIII
Hazard Class6.1(b)
Storage condition 储存温度-20°C 2-8°C
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 71,62,1941

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 15600 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 92,369,1948

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 5 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Vascular - regional or general arteriolar constriction
   Lungs, Thorax, or Respiration - acute pulmonary edema
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 92,108,1948

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 13 mg/kg
SEX/DURATION            : female 7-19 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - behavioral
REFERENCE :
   NYKZAU Nippon Yakurigaku Zasshi.  Japanese Journal of Pharmacology. (Nippon
   Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho,
   Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40-    1944- Volume(issue)/page/year:
   85,79,1985

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 3200 ng/kg
SEX/DURATION            : female 16 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
   PRGLBA Prostaglandins.  (Geron-X, Inc., P.O. Box 1108, Los Altos, CA 94022)
   V.1-    1972-  Volume(issue)/page/year: 2,295,1972

其他信息

  • Sigma Aldrich:55-27-6(sigmaaldrich)
  • MOL 文件:55-27-6.mol
  • color:off-white to tan
  • F:10

系列性分类


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