4-Acetamido-N-(2-(Diethylamino)Ethyl)Benzamide Hydrochloride 4-乙酰氨基-N-(2-(二乙氨基)乙基)苯甲酰胺盐酸盐
CAS 34118-92-8 MFCD00012501
化学结构图
SMILES: Cl.CC(=O)NC1C=CC(=CC=1)C(=O)NCCN(CC)CC
化学属性
| Mol. Formula | C15H24ClN3O2 |
|---|---|
| Mol. Weight | 314 |
| Melting Point | 184-186 °C(lit.) |
别名和识别编码
| Chemical Name | 4-Acetamido-N-(2-(Diethylamino)Ethyl)Benzamide Hydrochloride |
|---|---|
| Synonym | N-乙酰普卡胺 盐酸盐 NAPA 乙酰卡尼 盐酸盐 N-乙酰普鲁卡因胺 盐酸盐 |
| MDL Number | MFCD00012501 |
| PubChem Substance ID | 24852214 |
| CAS Number | 34118-92-8 |
| EC Number | 251-831-2 |
| Chemical Name Translation | 4-乙酰氨基-N-(2-(二乙氨基)乙基)苯甲酰胺盐酸盐 |
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分类
- {SNA} A-AM, Amides, Bioactive Small Molecules, Building Blocks, C8 to C20+, Carbonyl Compounds, Cell Biology, Chemical Synthesis, Organic Building Blocks
- A-AM, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Ion Channels, Monovalent Ion Channels, Potassium Channel Modulators, Voltage-gated Ion Channels
- {SNA} A-AM, Bioactive Small Molecule Alphabetical Index, Ion Channels, Monovalent Ion Channels, Potassium Channel Modulators, Voltage-gated Ion Channels, 生物活性小分子, 细胞信号转导和神经科学, 细
相关文献及参考
- Kamath, B.L., et al., Pharmacokinetics of procainamide and N-acetylprocainamide in rats J. Pharm. Sci. 70 , 299-302, (1981)
- Jung, D., et al., Disposition of procainamide and N-acetylprocainamide in protein-calorie malnutrition Drug Metab. Dispos. 13 , 359-63, (1985)
- Geelen, P., et al., Concomitant block of the rapid (I(Kr)) and slow (I(Ks)) components of the delayed rectifier potassium current is associated with additional drug effects on lengthening of cardiac repolarization. J. Cardiovasc. Pharmacol. Ther. 4 , 143, (1999)
- Richardson, B., et al., N-acetylprocainamide is a less potent inducer of T cell autoreactivity than procainamide. Arthritis Rheum. 31 , 995-999, (1998) 摘要
- Komeichi, K., et al., Effects of N-acetylprocainamide and sotalol on ion currents in isolated guinea-pig ventricular myocytes. Eur. J. Pharmacol. 187 , 313-322, (1990) 摘要
- Merck 14 ,20
- FT-IR 2 (2), 3004:B / FT-NMR 1 (2), 1398:A / IR-Spectra (3), 1080:E / RegBook 1 (2), 2021:F / Structure Index 1 , 322:A:7
