CAS 51-83-2 MFCD00012011-Ethanaminium,2-[(aminocarbonyl)oxy]-N,N,N-trimethyl-,chloride (2-氨基甲酰氧乙基)三甲基氯化铵 TAO{mole}

Ethanaminium,2-[(aminocarbonyl)oxy]-N,N,N-trimethyl-,chloride (2-氨基甲酰氧乙基)三甲基氯化铵

CAS 51-83-2 MFCD00012011

化学结构图

SMILES: C[N+](C)(C)CCOC(N)=O.[Cl-]

化学属性

Mol. Formula	C6 H15 N2 O2 . Cl
Mol. Weight	182.65
Melting Point	194 - 199ºC
TSCA	Yes
Solubility	1.0 G/ML
Appearance	crystalline
Boiling Point
Flash Point	-

别名和识别编码

Chemical Name	Ethanaminium,2-[(aminocarbonyl)oxy]-N,N,N-trimethyl-,chloride
CAS Number	51-83-2
Synonym	######## (2-CARBAMOYLOXYETHYL)TRIMETHYLAMMONIUM CHLORIDE (2-HYDROXYETHYL)TRIMETHYLAMMONIUM CHLORIDE CARBAMATE (2-Hydroxyethyl)tri (2-Hydroxyethyl)trimethylammonium chloride carbamate; Carbamylcholine chloride (2-氨基甲酰氧乙基)三甲基氯化铵 2-((aminocarbonyl)oxy)-n,n,n,-trimethyl-ethanaminiuchloride 2-((aminocarbonyl)oxy)-n,n,n-trimethylethana 2-((aminocarbonyl)oxy)-n,n,n-trimethylethanam 2-(aminocarbonyl)oxy-n,n,n-trimethyl-ethanaminiuchlor 2-[(Aminocarbonyl)oxy]-N,N,N-trimethyle-thanaminiumchlorid 2-[(aminocarbonyl)oxy]-n,n,n-tri CARBACHOL CARBAMOYLCHOLINE CHLORIDE CARBAMYLCHOLINE CHLORIDE CH CHOLINE CHLORIDE CARBAMATE CHOLINE CHLORIDE CARBAMATER Ca Car Carbachol Carbachol chloride
MDL Number	-
EC Number	200-127-3
Merck Number	1779
Beilstein Registry Number	4(4)1455
PubChem Substance ID	87565693
Chemical Name Translation	(2-氨基甲酰氧乙基)三甲基氯化铵
Wiswesser Line Notation	ZVO2K1&1&1 &Q &G
LabNetwork Molecule ID	LN01262961
Reaxys-RN	3917459
InChI	InChI=1S/C6H14N2O2.ClH/c1-8(2,3)4-5-10-6(7)9;/h4-5H2,1-3H3,(H-,7,9);1H
Canonical SMILES	-

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品牌质保精细包装现货库存一流品牌服务

产品应用

Carbamylcholine Chloride is a cholinergic receptor agonist. Studies show that Carbamylcholine Chloride is resistant to the action of cholinesterases. Carbamylcholine Chloride also displays antiapoptot

安全信息

RTECSGA0875000

Safety Statements

S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
S36 Wear suitable protective clothing 穿戴适当的防护服；
S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后，立即用大量…（由生产厂家指定）冲洗；
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；

Packing GroupII

UN Number 2811 UN 2811 6.1/PG 2 UN2811

Risk Statements

R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
R25 Toxic if swallowed 吞咽有毒

Storage condition -20 -20°C -20°C, Hygroscopic -20℃ Hygroscopic

GHS Symbol

WGK Germany3

Hazard statements

H300 Fatal if swallowed 吞食致命

Personal Protective Equipment Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Precautionary statements

P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
P301+P310
P301+P310+P330
P405 Store locked up. 上锁保管。
P501 Dispose of contents/container to..… 处理内容物/容器.....

Signal word Danger

Hazard Codes T

Hazard Class6.1

Restrict 剧毒化学品

Warnings 危化品目录(2015) 危险化学品

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 58,337,1936

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 2857 ng/kg
TOXIC EFFECTS :
   Vascular - BP lowering not characterized in autonomic section
REFERENCE :
   CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses
   Filiales.  (SPPIF, B.P.22, F-41353 Vineuil, France)  V.1-    1849-
   Volume(issue)/page/year: 113,79,1933

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 50 ug/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   FATOAO Farmakologiya i Toksikologiya (Moscow).  For English translation, see
   PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2-   
   1939-  Volume(issue)/page/year: 20(4),32,1957

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 1428 ng/kg
TOXIC EFFECTS :
   Vascular - BP lowering not characterized in autonomic section
   Vascular - regional or general arteriolar or venous dilation
   Gastrointestinal - nausea or vomiting
REFERENCE :
   CRSBAW Comptes Rendus des Seances

其他信息

急性毒性:口服-大鼠 LD50: 40 毫克/公斤; 口服-小鼠 LD50: 15 毫克/公斤
毒性分级:剧毒
可燃性危险特性:热分解排出有毒氮氧化物, 氯化物烟雾
上游原料:尿素 --> 2-氯乙醇 --> 三甲胺 --> 氯化胆碱
类别:有毒物质
MOL 文件:51-83-2.mol
卡巴胆碱价格(试剂级):更新日期产品编号产品名称包装价格 2010/06/21 108240050 卡巴胆碱 Carbamylcholine chloride 99% 5 GR 699元
灭火剂:水, 二氧化碳, 泡沫, 干粉
图谱信息:卡巴胆碱(51-83-2)质谱(MS) 卡巴胆碱(51-83-2)红外图谱(IR1) 卡巴胆碱(51-83-2)红外图谱(IR2)
储运特性:库房低温通风干燥; 与食品原料分开存放
方法一:以β-氯乙醇为原料，经光气酰化，制得氯甲酸-β-氯乙酯：然后与氨反应生成氨基甲酸-β-氯乙酯，最后与三甲胺成季铵盐反应而得卡巴胆碱：卡巴胆碱的另一种制法是采用氯化胆碱和尿素为原料：当采用配料比氯化胆碱：尿素：亚硝酸钠：硫酸=1：1：1.15：1.35，在60℃反应约40h，能以71%的收率获得得卡巴胆碱。
color:white
用途一:该品为拟胆碱药，也用作副交感神经兴奋药。作兽药时用于大动物，治疗马的急性腹痛等。小鼠口服LD50为15mg/kg，静脉注射为0.3mg/kg。
Alfa Aesar:卡巴可,99% Carbachol, 99%(51-83-2)
敏感性:Hygroscopic
Sigma Aldrich:51-83-2(sigmaaldrich)
Acros Organics:Carbamylcholinechloride,99%(51-83-2)