CAS 51-15-0 MFCD00011981-2-((Hydroxyimino)Methyl)-1-Methylpyridin-1-Ium Chloride 1-甲基吡啶-2-醛肟氯鎓盐 TAO{mole}

2-((Hydroxyimino)Methyl)-1-Methylpyridin-1-Ium Chloride 1-甲基吡啶-2-醛肟氯鎓盐

CAS 51-15-0 MFCD00011981

化学结构图

SMILES: C[n+]1ccccc1/C=N/O.[Cl-]

化学属性

Mol. Formula	C7H9ClN2O
Mol. Weight	173
Melting Point	230 °C(lit.)
TSCA	No
Solubility	65.5 G/100 ML (25 ºC)
Appearance	黄白色结晶性粉末。熔点235-238℃（分解）。在25℃水中溶解度为640mg/ml。

别名和识别编码

Chemical Name	2-((Hydroxyimino)Methyl)-1-Methylpyridin-1-Ium Chloride
CAS Number	51-15-0
Synonym	1-Methylpyridinium-2-aldoxime Chloride 1-methyl-2-formylpyridiniumchlorideoxime Pyridinium, 2-((hydroxyimino)methyl)-1-methyl-, chloride 1-methyl-2-aldoximinopyridiniumchloride 1-Methyl-2-formylpyridinium chloride oxime 2-(Hydroxyiminomethyl)-1-methylpyridinium chloride PYRIDINE-2-CARBOXALDOXIME METHOCHLORIDE 2-[(Hydroxyimino)methyl]-1-methylpyridiniumchloride 2-Formy 2-PAM chloride 2-PYRIDINEALDOXIME METHOCHLORIDE 1-methyl-2-pyridiniumaldoximechloride {Chemicalb N-Methylpyridinium chloride 2-aldoxime 2-吡啶醛 2-吡啶醛肟甲氯, 97% 2-Pam 2-Pyridine-aldoxime chloride PYRIDINE-2-CARBALDOXIME METHOCHLORIDE 2-Formyl-1-methyl-pyridinium Chloride Oxime Protopam Chloride 1-Methyl-2-aldoximinopyridinium chloride 2-Formyl-1-methylpyridinium chloride oxime 1-Methyl-2-pyridinium aldoxime chloride Pyridinium aldoxime methochloride 2-PAM 氯化物氯解磷定 PYRIDINE-2 {C 2-PAM chloride; Pralidoxime chloride Protopam chloride 2-pyridinealdoximemethylchloride 吡啶-2-甲醛肟甲氯化物 n-methylpyridiniumchloride2-al Pralidoxime chloride 2-吡啶醛肟甲氯 {h 2-[(Hydroxyimino)methyl]-1-methyl-pyridinium Chloride 2-formyl-1-methylpyridiniumchlorideoxime 1-METHYLPYRIDINIUM-2-ALDOXIME CHLORIDE 2-Pyridinealdoxime Metho Pyridine-2-aldoxime methochloride 2-PAM 2-(hydroxyiminomethyl 消磷灵吡啶-2-甲醛肟氯甲烷盐 N-METHYLPYRIDINIUM-2-ALDOXIME CHLORIDE PAM CHLORIDE 氯解磷定
MDL Number	MFCD00011981
PubChem Substance ID	135445761
EC Number	200-080-9
Merck Number	7703
Beilstein Registry Number	4163981
Reaxys-RN	4163981
Chemical Name Translation	1-甲基吡啶-2-醛肟氯鎓盐
Wiswesser Line Notation	T6KJ A1 B1UNQ &G
InChIKey	HIGSLXSBYYMVKI-UHFFFAOYSA-N
InChI	InChI=1S/C7H8N2O.ClH/c1-9-5-3-2-4-7(9)6-8-10;/h2-6H,1H3;1H

信息真实价格透明资金保障专业采购外包团队在线服务

品牌质保精细包装现货库存一流品牌服务

产品应用

This compound binds to inactivated acetylcholinesterases and is used to combat poisoning from organophosphates and nerve agents

安全信息

WGK Germany1

GHS Symbol

Precautionary statements

P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P302+P352+P332+P313+P362+P364
P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。
P332+P313
P305+P351+P338+P337+P313
P302+P350
P337+P313
P305+P351+P338

Hazard statements

H332 Harmful if inhaled 吸入有害
H302 Harmful if swallowed 吞食有害
H312 Harmful in contact with skin 皮肤接触有害
H303 May be harmfully swallowed 吞食可能有害

RTECSUU4200000

Signal word Warning

Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves

Safety Statements

S36 Wear suitable protective clothing 穿戴适当的防护服；
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
S37 Wear suitable gloves 戴适当手套；
S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护；
S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；
S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；

Risk Statements

R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
R20/22 Harmful by inhalation and if swallowed 吸入和不慎吞咽有害
R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
R22 Harmful if swallowed 吞咽有害

Hazard Codes Xn

Storage condition 0-6°C

{h

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 90 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 14,5,1964

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 14 mg/kg
TOXIC EFFECTS :
   Behavioral - coma
   Lungs, Thorax, or Respiration - bronchiolar constriction
   Lungs, Thorax, or Respiration - cyanosis
REFERENCE :
   34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York,
   Academic Press, Inc., 1969  Volume(issue)/page/year: -,449,1969

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intramuscular
SPECIE

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 96 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   16,40,1970

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DCTODJ Drug and Chemical Toxicology.  (Marcel Dekker, 270 Madison Ave., New
   York, NY 10016) V.1-    1977/78-  Volume(issue)/page/year: 8,431,1985

其他信息

上游原料:乙醇溶液 --> 2-甲基吡啶 --> 亚硝酸乙酯
TCI Shanghai:1-甲基吡啶-2-醛肟氯盐 1-Methylpyridinium-2-aldoxime Chloride,>;97.0%(T)(51-15-0)
2-吡啶醛肟甲氯价格(试剂级):更新日期产品编号产品名称包装价格 2014/06/02 M0819 1-甲基吡啶-2-醛肟氯盐 1-Methylpyridinium-2-aldoxime Chloride 25G 652元 2010/06/21 157670050 2-吡啶醛肟甲氯 2-Pyridinealdoxime methochloride 99% 5 GR 495元 2010/05/25 B23890 2-吡啶醛肟甲氯, 97% Pyridine-2-carboxaldoxime methochloride, 97% 25g 1596元
Alfa Aesar:2-吡啶醛肟甲氯,97% Pyridine-2-carboxaldoxime methochloride, 97%(51-15-0)
MOL 文件:51-15-0.mol
下游产品:2-吡啶乙肪醛甲碘化物
2-吡啶醛肟甲氯价格(试剂级):更新日期产品编号产品名称包装价格 2011/04/16 M0819 1-甲基吡啶-2-醛肟氯盐 1-Methylpyridinium-2-aldoxime Chloride 25G 1010元 2010/06/21 157670050 2-吡啶醛肟甲氯 2-Pyridinealdoxime methochloride 99% 5 GR 495元 2010/05/25 B23890 2-吡啶醛肟甲氯, 97% Pyridine-2-carboxaldoxime methochloride, 97% 25g 1596元
用途一:用于有机磷中毒的解毒剂。
Sigma Aldrich:51-15-0(sigmaaldrich)
方法一:2-甲基吡啶与氯甲烷反应得2-甲基吡啶氯甲烷盐，使基与亚硝酸乙酯进行亚硝化反应得到氯解磷定钠盐，然后在乙醇溶液中用浓盐酸中和至pH=3-4，滤去氯化钠，滤液减压浓缩回收乙醇，得氯解磷定粗品，经蒸馏水溶解、活性炭脱色、重结晶得成品。
图谱信息:2-吡啶醛肟甲氯(51-15-0)核磁图( 13 CNMR) 2-吡啶醛肟甲氯(51-15-0)红外图谱(IR2) 2-吡啶醛肟甲氯(51-15-0)核磁图( 1 HNMR) 2-吡啶醛肟甲氯(51-15-0)红外图谱(IR1) 2-吡啶醛肟甲氯(51-15-0)质谱(MS)
Acros Organics:2-吡啶醛肟甲氯 2-Pyridinealdoxime methochloride, 99%(51-15-0)