N-Succinimidyl 4-(N-Maleimidomethyl)Cyclohexane-1-Carboxylate 4-(N-马来酰亚胺基甲基)环己烷-1-羧酸琥珀酰亚胺酯
CAS 64987-85-5 MFCD00009634
化学结构图
SMILES: O=C(ON1C(=O)CCC1=O)C1CCC(CN2C(=O)C=CC2=O)CC1
化学属性
| Mol. Formula | C16H18N2O6 |
|---|---|
| Mol. Weight | 334 |
| Melting Point | 176-180 |
| TSCA | No |
| Density | 1.422 |
别名和识别编码
| Chemical Name | N-Succinimidyl 4-(N-Maleimidomethyl)Cyclohexane-1-Carboxylate |
|---|---|
| CAS Number | 64987-85-5 |
| Synonym | 4-(N-Maleimidomethyl)-cyclohexane-1-carboxylic acid N-hydroxysuccinimide ester 4-(N-Maleimidomethyl)cyclohexane-1-carboxylic Acid N-Hydroxysuccinimide Ester 4-(N-马来酰亚胺基甲基)环己烷-1-羧酸琥珀酰亚胺酯 N-琥珀酰亚胺基4-(马来酰亚胺基甲基)环己烷羧酸酯 SMCC SMCC |
| PubChem Substance ID | 135727275 |
| Beilstein Registry Number | 1555271 |
| MDL Number | MFCD00009634 |
| Reaxys-RN | 1555271 |
| EC Number | 250-023-7 |
| Chemical Name Translation | 4-(N-马来酰亚胺基甲基)环己烷-1-羧酸琥珀酰亚胺酯 |
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资金保障
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分类
- {SNA} Chemical Biology, Chemical Synthesis, Crosslinkers, Crosslinking, Crosslinking Reagents, Heterobifunctional Cross-Linking Reagents, Heterobifunctional Crosslinking Reagents, Linkers and Crosslinkers, Molecular Biology, Protein Interaction, Protein Modification, Protein Structural Analysis,
产品应用
- A sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent. It conjugates anti-digoxin F(ab?)2 fragments to ?-galactosidase. Conjugates hIgG to alkaline phosphatase.
相关文献及参考
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- Yoshitake, S., et al., Mild and efficient conjugation of rabbit Fab' and horseradish peroxidase using a maleimide compound and its use for enzyme immunoassay. J. Biochem. 92 , 1413-1424, (1982) 摘要
- Corp MSDS 1 (2), 2186:A / RegBook 1 (1), 929:C / Sigma FT-IR 1 (2), 692:A / Structure Index 1 , 144:A:6
安全信息
GHS Symbol
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P302+P352+P332+P313+P362+P364
- P304+P340
- P305+P351+P338
- P305+P351+P338+P337+P313
- P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
- P405 Store locked up. 上锁保管。
- P501a
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S37 Wear suitable gloves 戴适当手套；
- S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
