Trimethylsilyl Acetate 三甲基硅乙酸酯

CAS 2754-27-0 MFCD00008695

化学结构图

2754-27-0
SMILES: CC(=O)O[Si](C)(C)C

化学属性

Mol. FormulaC5H12O2Si
Mol. Weight132.23
Refractive index1.3870 to 1.3900
Boiling Point107-108
Density0.882
Melting Point-32
Flash Point4°C(lit.)
TSCAYes
Vapor Density1 (vs air)
Vapor Pressure35 mmHg ( 30 °C)
Solubility起反应
Danger-Level甲类

别名和识别编码

Chemical NameTrimethylsilyl Acetate
CAS Number2754-27-0
PubChem Substance ID87563010
EC Number220-404-2
Beilstein Registry Number1744463
MDL NumberMFCD00008695
Reaxys-RN1744463
Synonym Trimethylsilyl acetate {LY} Trimethylsilyl acetate {} {LY} Trimethylsilyl acetate {} {} {LY} Trimethylsilyl acetate {} {} {} {LY} Trimethylsilyl acetate {} {} {} {} {LY} Trimethylsilyl acetate {} {} {} {} {} {LY} Trimethylsilyl acetate {} {} {} {} {} {} {LY} Trimethylsilyl acetate {} {} {} {} {} {} {} {LY} Trimethylsilyl acetate {} {} {} {} {} {} {} {} {LY} Trimethylsilyl acetate {} {} {} {} {} {} {} {} {} {LY} Trimethylsilyl acetate {} {} {} {} {} {} {} {} {} {} {LY} Trimethylsilyl acetate {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Trimethylsilyl acetate {} {} {} {} {} {} {} {} {} {} {} {} {LY} Trimethylsilyl acetate {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Trimethylsilyl acetate {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Trimethylsilyl acetate {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Trimethylsilyl acetate {} {} {} {} {} {} {} {} {
Chemical Name Translation三甲基硅乙酸酯
InChIKeyQHUNJMXHQHHWQP-UHFFFAOYSA-N
LabNetwork Molecule IDLN01740095
Canonical SMILESCC(O[Si](C)(C)C)=O
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分类

  • {uni_hamburg} no charge; ester; 1fragment
  • Building Blocks, C2 to C5, Carbonyl Compounds, Chemical Synthesis, Esters, Organic Building Blocks
  • {SA} Building Blocks, C2 to C5, Carbonyl Compounds, Chemical Synthesis, Esters, Organic Building Blocks

相关文献及参考

  • Short: III/35F
  • Beilstein:4(4)4003
  • Lithiation and acylation give the TMS esters of ß-keto acids, which can be converted to the unstable ß-keto acids themselves, or directly to methyl ketones: Synth. Commun., 13, 183 (1983).
  • Short: III/35E
  • Has been used in a 2-carbon homologation sequence for the synthesis of (E)-alkenoic acids via silyl ketene acetals: J. Org. Chem., 63, 8785 (1998):

安全信息

GHS Symbol
WGK Germany3
Hazard statements
  • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Hazard Codes 3 F
Precautionary statements
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P332+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P370+P378
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word Danger
Safety Statements
  • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
  • S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
Risk Statements
  • R11 Highly flammable 非常易燃
UN Number 3272
Storage condition 2-8°C {LY} 2-8°C Flammables area Moisture Sensitive {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C
Packing GroupII
Hazard Class3

其他信息

  • 蒸气压:35 mm Hg ( 30 °C)
  • Acros Organics:三甲基硅乙酸酯 Trimethylsilyl acetate, 97%(2754-27-0)
  • MOL 文件:2754-27-0.mol
  • 三甲基硅乙酸酯价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 A1567 乙酸三甲基硅酯 Trimethylsilyl Acetate 25ML 299元 2014/06/02 A1567 乙酸三甲基硅酯 Trimethylsilyl Acetate 250ML 1630元 2010/06/21 391980250 三甲基硅乙酸酯 Trimethylsilyl acetate 97% 25 GR 270元
  • 图谱信息:三甲基硅乙酸酯(2754-27-0)质谱(MS)
  • 和水反应。
  • TCI Shanghai:乙酸三甲基硅酯 Trimethylsilyl Acetate,>;98.0%(GC)(2754-27-0)
  • 蒸气密度:1 (vs air)
  • Sigma Aldrich:2754-27-0(sigmaaldrich)
  • F:10-21
  • Alfa Aesar:乙酸三甲基硅酯,98% Trimethylsilyl acetate, 98%(2754-27-0)
  • 敏感性:Moisture Sensitive
  • TSCA:Yes

系列性分类


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