CAS 108-38-3 MFCD00008536-M-Xylene 间二甲苯(易涉毒) TAO{mole}

M-Xylene 间二甲苯(易涉毒)

CAS 108-38-3 MFCD00008536

化学结构图

SMILES: CC1=CC(C)=CC=C1

化学属性

Mol. Formula	C8H10
Mol. Weight	106
Refractive index	1.4950 to 1.4980
Boiling Point	139
Density	0.864
Melting Point	-48
Flash Point	28°C(lit.)
TSCA	Yes
Autoignition Point	982 °F
Vapor Density	3.7 (vs air)
Vapor Pressure	16 mmHg ( 37.7 °C)
Solubility	不溶于水，可混溶于乙醇、乙醚、氯仿等多数有机溶剂。
Stability	对光敏感

别名和识别编码

Chemical Name	M-Xylene
Synonym	m-Dimethylbenzol 1,3-dimethylbenzene M-METHYLTOLUENE M-XYLENE OEKANAL 间二甲苯标准溶液 M-XYLENE, REAGENTPLUS, 99% 1,3-二甲基苯;1,3-二甲苯 M-XYLENE, 1X1ML, MEOH, 200UG/ML M-XYLENE DISTILLED 1 L m-xylene [srp]m-methyltoluene {Chemi 1,3-dimethyl-benzene 间二甲苯标准溶液;1,3-二甲基苯;1,3-二甲苯 1，3-二甲苯，间二甲苯 1，3-Xylene 3-xylene 1,3-DIMETHYLBENZENE m-Methyltoluene 1,3-Dimethylbenzol 1,3-Xylene META-XYLENE m-Xylol M-xylene μ-Xylene m-Dimethylbenzene 1,3-dimethyl-benzen Benzene,1,3-dimethyl- 间二甲苯 be
CAS Number	108-38-3
PubChem Substance ID	87577880
EC Number	203-576-3
Beilstein Registry Number	605441
MDL Number	MFCD00008536
Reaxys-RN	605441
Merck Number	10081
Chemical Name Translation	间二甲苯(易涉毒)
Wiswesser Line Notation	1R C1
LabNetwork Molecule ID	LN00163553

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品牌质保精细包装现货库存一流品牌服务

产品应用

溶剂。有机合成。测定矿物的折光率。气相色谱分析标准。清洗剂。

安全信息

GHS Symbol

WGK Germany2

Hazard Codes 3

Hazard statements

H226 Flammable liquid and vapour 易燃液体和蒸气
H312+H332
H315 Causes skin irritation 会刺激皮肤
H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
H304 May be fatal if swallowed and enters airways 吞食和进入呼吸道可能致命
H335 May cause respiratory irritation 可能导致呼吸道刺激
H412 Harmfutoaquaticlifewithlonglastingeffects 对水生生物有害并具有长期影响。
H319 Causes serious eye irritation 严重刺激眼睛
H332 Harmful if inhaled 吸入有害
H312 Harmful in contact with skin 皮肤接触有害

Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

RTECSZE2275000

Precautionary statements

P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
P241+P242+P243
P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
P273 Avoid release to the environment. 避免释放到环境中。
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P301+P310
P302+P352+P332+P313+P362+P364
P303+P361+P353
P304+P340+P312
P305+P351+P338
P305+P351+P338+P337+P313
P308+P311
P331 Do NOT induce vomiting.. 不要催吐。
P332+P313
P337+P313
P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
P370+P378
P403+P233
P501 Dispose of contents/container to..… 处理内容物/容器.....

Signal word Danger Warning

UN Number 1307 UN1307

Risk Statements

R10 Flammable 易燃
R20/21 Harmful by inhalation and in contact with skin 吸入及与皮肤接触有害
R38 Irritating to skin 刺激皮肤

Safety Statements

S25 Avoid contact with eyes 避免眼睛接触；

Packing GroupIII

Hazard Class3

Storage condition 密封阴凉保存。储存温度2-8℃ 0-6°C

Warnings 危化品目录(2015)

TYPE OF TEST            : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 8000 ppm/4H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIHAAP American Industrial Hygiene Association Journal.  (AIHA, 475 Wolf
   Ledges Pkwy., Akron, OH 44311)  V.19-    1958-  Volume(issue)/page/year:
   23,95,1962

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TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 14100 uL/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIHAAP American Industrial Hygiene Association Journal.  (AIHA, 475 Wolf
   Ledges Pkwy., Akron, OH 44311)  V.19-    1958-  Volume(issue)/page/year:
   23,95,1962

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YAKUD5 Gekkan Yakuji.  Pharmaceuticals Monthly.  (Yakugyo Jihosha, Inaoka
   Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan)  V.1-   1959-
   Volume(issue)/page/year: 22,883,1980

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2003 uL/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARTODN Archives of Toxicology.  (Springer-Verlag, Heidelberger Pl. 3, D-1000
   Berlin 33, Fed. Rep. Ger.)  V.32-    1974-  Volume(issue)/page/year:
   58,106,1985

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPO

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 500 mg/m3/12H
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   ATSUDG Archives of Toxicology, Supplement.  (Springer-Verlag New York, Inc.,
   Service Center, 44 Hartz Way, Secaucus, NJ 07094)  No.1-    1978-
   Volume(issue)/page/year: 8,425,1985

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 30 mg/kg
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured
   before birth)
REFERENCE :
   APTOD9 Abstracts of Papers, Society of Toxicology.  Annual Meetings.
   (Academic Press, Inc., 1 E. First St., Duluth, MN 55802)
   Volume(issue)/page/year: 19,A22,1980

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rabbit
DOSE                    : 500 mg/m3/24H
SEX/DURATION            : female 7-20 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
   Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
   ATSUDG Archives of Toxicology, Supplement.  (Springer-Verlag New York, Inc.,
   Service Center, 44 Hartz Way, Secaucus, NJ 07094)  No.1-    1978-
   Volume(issue)/page/year: 8,425,1985

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSU

Restrict 危险品

其他信息

方法一:其制备方法是利用石油二甲苯或煤焦油二甲苯进行分离，分离的方法可以用低温结晶法、配合法、吸附法和磺化水解法等。国内过去用磺化水解法生产间二甲苯，现在已采用吸附法分离间二甲苯。吸附法用分子筛为吸附剂，可以进行气相吸附，也可以进行液相吸附，其工艺分述如下。 (1)磺化水解法将混合二甲苯经精馏切取130～140℃馏分，再加硫酸磺化，反应温度80～90℃，反应时间3.5h，然后分出磺化二甲苯，再经水解、蒸馏，切取140～150℃馏分而得成品。该方法对设备腐蚀严重，并有较多的三废，仅能小规模生产，因此被吸附法所取代。 (2)吸附法采用分子筛进行液相吸附或气相吸附，液相吸附以K-Ba-Y型为吸附剂，甲苯为解吸剂，在移动床进行连续吸附分离，操作温度65～85℃，吸附剂与原料比不大于10，脱附剂与原料比大于5。气相吸附也采用K-Ba-Y型分子筛为吸附剂，吸附温度170～180℃，操作压力为常压。吸附分离法是近代分离二甲苯的新方法。
毒性分级:中毒
方法二:1.将混合二甲苯精馏，切取130-140℃馏分，再加硫酸磺化，反应温度80-90℃，反应3.5h，然后分出未磺化的二甲苯，再经水解、蒸馏，切取140-150℃馏分而得成品。2.原料甲苯在烷基转移反应器中，进行烷基转移反应，生成二甲苯和苯。混合二甲苯在
TCI Shanghai:间二甲苯(1mg/ml的甲醇溶液)[用于水分析] m-Xylene (1mg/ml in Methanol) [for Water Analysis](108-38-3)
刺激数据:皮肤- 兔子 20 毫克/24 小时中度; 眼睛- 兔子 5 毫克/ 24小时轻度
蒸气压:16 mm Hg ( 37.7 °C)
职业标准:TWA 435 毫克/ 立方米
储运特性:库房通风低温干燥; 与氧化剂分开存放
类别:较易燃液体
用途二:用作分析试剂和精密光学仪器的溶剂和清洗剂，也用于有机合成
蒸气密度:3.7 (vs air)
方法一:其制备方法是利用石油二甲苯或煤焦油二甲苯进行分离，分离的方法可以用低温结晶法、配合法、吸附法和磺化
灭火剂:干粉、干砂、二氧化碳、泡沫、1211灭火剂
爆炸物危险特性:与空气混合可爆
{Chemicalb
用途四:主要作溶剂，用于生产间苯二甲酸进而生产不饱和聚酯树脂和涂料，还用于生产间甲基苯甲酸、间苯二甲腈，医药利多卡因、氧甲唑啉，新泛影等。还可用于香料、彩色电影胶片的油溶性成色剂等的原料和染料中间体。由于生产间二甲苯的技术难度大，我国产量很少，无论产量还是质量都不能满足市场需要。
用途五:溶剂。有机合成。测定矿物的折光率。气相色谱分析标准。清洗剂。
无色透明液体。能与醇、醚和其他许多有机溶剂混和，不溶于水。能燃烧。低毒，半数致死量（大鼠，经口）4000mg/kg。有刺激性。
图谱信息:间二甲苯(108-38-3)红外图谱(IR1) 间二甲苯(108-38-3)核磁图( 13 CNMR) 间二甲苯(108-38-3)Raman光谱间二甲苯(108-38-3)质谱(MS) 间二甲苯(108-38-3)核磁图( 1 HNMR)
下游产品:对二甲苯 --> 1,2-二甲苯 --> 2,6-二甲基苯胺 --> 甲霜灵 --> 间苯二甲酸 --> 双甲眯 --> 4-溴-3-甲基苄胺 --> 百菌清 --> 均苯四甲酸二酐 --> 1,2,4,5-四甲苯 --> 间苯二甲腈 --> 间甲基苯甲酸 --> 2,4-二甲基苯胺 --> 二甲苯麝香 --> N-(2,4-二甲苯基)-N'-甲基甲脒盐酸盐 --> 1,4-双(三氯甲基)苯 --> 对氯苯氧乙酸二甲胺基乙酯 --> 酮麝香 --> 1,3-二甲基-4-硝基苯 --> 5-叔丁基-苯乙烯 --> 2,6-二氰基-4-硝基苯胺 --> 2,6-二甲基硝基苯 --> 3,
外观性质:无色透明液体，有类似甲苯的气味。
间二甲苯价格(试剂级):更新日期产品编号产品名称包装价格 2011