Methyl 3,4,5-trimethoxybenzoate methyl 3,4,5-trimethoxybenzoate
CAS 1916-07-0 MFCD00008431
化学结构图
SMILES: COC(=O)c1cc(OC)c(OC)c(OC)c1
化学属性
| Mol. Formula | C11H14O5 |
|---|---|
| Mol. Weight | 226.23 |
| Boiling Point | 274.5 °C at 760 mmHg |
| Melting Point | 81-85 °C |
| TSCA | Yes |
| Density | 1.422 |
| Flash Point | 274-275°C |
别名和识别编码
| Chemical Name | Trimethylgallic Acid Methyl Ester |
|---|---|
| CAS Number | 1916-07-0 |
| Synonym | Methyl 3,4,5-trimethoxybenzoate {LY} Methyl 3,4,5-trimethoxybenzoate {} {LY} Methyl 3,4,5-trimethoxybenzoate {} {} {LY} Methyl 3,4,5-trimethoxybenzoate {} {} {} {LY} Methyl 3,4,5-trimethoxybenzoate {} {} {} {} {LY} Methyl 3,4,5-trimethoxybenzoate {} {} {} {} {} {LY} Methyl 3,4,5-trimethoxybenzoate {} {} {} {} {} {} {LY} Methyl 3,4,5-trimethoxybenzoate {} {} {} {} {} {} {} {LY} Methyl 3,4,5-trimethoxybenzoate {} {} {} {} {} {} {} {} {LY} Methyl 3,4,5-trimethoxybenzoate {} {} {} {} {} {} {} {} {} {LY} Methyl 3,4,5-trimethoxybenzoate {} {} {} {} {} {} {} {} {} {} {LY} Methyl 3,4,5-trimethoxybenzoate {} {} {} {} {} {} {} {} {} {} {} {LY} Methyl 3,4,5-trimethoxybenzoate {} {} {} {} {} {} {} {} {} {} {} {} {LY} Methyl 3,4,5-trimethoxybenzoate {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Methyl 3,4,5-trimethoxybenzoate {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Methyl 3,4,5-trimethoxybe |
| MDL Number | MFCD00008431 |
| PubChem Substance ID | 15956 |
| EC Number | 217-629-3 |
| Beilstein Registry Number | 2218156 |
| Reaxys-RN | 2218156 |
| Chemical Name Translation | methyl 3,4,5-trimethoxybenzoate |
| Wiswesser Line Notation | 1OVR CO1 DO1 EO1 |
| LabNetwork Molecule ID | LN00222665 |
| InChI | InChI=1S/C11H14O5/c1-13-8-5-7(11(12)16-4)6-9(14-2)10(8)15-3/h5-6H,1-4H3 |
| Canonical SMILES | O=C(OC)C1=CC(OC)=C(OC)C(OC)=C1 |
信息真实价格透明
资金保障
专业采购外包团队在线服务
信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- Pharmaceuticals
- Aromatics
- Intermediates & Fine Chemicals
- Impurities
- {SNA} Building Blocks, C10 to C11, Carbonyl Compounds, Chemical Synthesis, Esters, Organic Building Blocks
产品应用
- Trimebutine (T795605) impurity standard.
相关文献及参考
- Chen, D., et al.: Bioorg. Med. Chem., 5, 1715 (1997),
- Min, H., et al.: Bioorg. Med. Chem. Lett., 18, 523 (2008),
- Wang, J., et al.: Br. J. Pharmacol., 113, 945 (1994),
安全信息
- S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
GHS Symbol
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 100 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#07253
其他信息
- 3,4,5-三甲氧基苯甲酸甲酯价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 T1092 3,4,5-三甲氧基苯甲酸甲酯 Methyl 3,4,5-Trimethoxybenzoate 500G 986元 2014/06/02 T1092 3,4,5-三甲氧基苯甲酸甲酯 Methyl 3,4,5-Trimethoxybenzoate 25G 156元 2010/06/21 127941000 3,4,5-三甲氧基苯甲酸甲酯 Methyl 3,4,5-trimethoxybenzoate 98% 100 GR 312元
- MSDS 信息:Methyl 3,4,5-trimethoxybenzoate(1916-07-0).msds
- TCI Shanghai:3,4,5-三甲氧基苯甲酸甲酯 Methyl 3,4,5-Trimethoxybenzoate,>;99.0%(GC)(1916-07-0)
- 下游产品:3,4,5-三甲氧基苯甲酰肼
- 用途二:该品是抗菌增效药甲氧苄氨嘧啶的中间体。
- 上游原料:硫酸二甲酯 --> 四丁基溴化铵 --> 单宁酸 --> 苯甲酸甲酯 --> 3,4,5-三甲氧基苯甲酸
- Hazard Note:Irritant
- 用途一:用作医药中间体，是抗焦虑药曲美托嗪、肠胃药马来酸曲美布汀等的主要原料
- Alfa Aesar:3，4，5-三甲氧基苯甲酸甲酯,98+% Methyl 3,4,5-trimethoxybenzoate, 98+%(1916-07-0)
- MOL 文件:1916-07-0.mol
- 方法一:由没食子酸与硫酸二甲酯进行甲基化反应制得。将水、没食子酸、硫酸二甲酯加入反应锅，于15-35℃下滴加氢氧化钠溶液，在40℃左右搅拌半小时。再加入第二批硫酸二甲酯，在40℃左右滴加氢氧化钠溶液至pH为8-9。继续反应1h后，冷却，过滤，洗涤，干燥，得三甲氧基苯甲酸甲酯，收率90%以上。上述甲基化、酯化反应，也可采用四丁基溴化铵作相转移催化剂，在水和氯仿中进行。该品也可采用单宁酸为原料或由3,4,5-三甲氧基苯甲酸与甲醇酯化来制取。
- Sigma Aldrich:1916-07-0(sigmaaldrich)
- Acros Organics:Methyl 3,4,5-trimethoxybenzoate, 98%(1916-07-0)
