CAS 79-46-9 MFCD00007397-2-Nitropropane 2-硝基丙烷 TAO{mole}

2-Nitropropane 2-硝基丙烷

CAS 79-46-9 MFCD00007397

化学结构图

SMILES: CC(C)[N+](=O)[O-]

化学属性

Mol. Formula	C₃H₇NO₂
Mol. Weight	89.09
Refractive index	1.3930 to 1.3970
Boiling Point	120 °C
Density	0.992 g/mL at 25 °C(lit.)
Melting Point
Autoignition Point	802 °F
Vapor Density	~3 (vs air)
Vapor Pressure	~13 mmHg ( 20 °C)
Flash Point	24°C(lit.)
Solubility	1.7 G/100 ML (20 ºC)
Danger-Level	甲类

别名和识别编码

Chemical Name	2-Nitropropane
CAS Number	79-46-9
PubChem Substance ID	398
EC Number	201-209-1
Beilstein Registry Number	1,116
MDL Number	MFCD00007397
Reaxys-RN	1740684
Merck Number	6628
Synonym	2-NITROPROPANE 2-NP 2-Nitropropane {Chemicalbook} Rcra waste number U171 b-nitropropane beta-Nitropropane i-C3H7NO2 nipars-20 nipars-20solvent nipars-30solvent rcrawastenumberu171 sec-Nitropropane {} {hazard_com} RCRA waste number U171 {} {} {Chemicalbook} Propane,2-nitr {} {} {} {uni_hamburg} Propane, 2-nitro- {} {} {} {} { {} {} {} {} {uni_hamburg} Nitroisopropane {} {} {} {} {} {Chemicalbook} Nipar S-30 solvent {} {} {} {} {} {} {Chemicalbook} Nipar S-20 solvent {} {} {} {} {} {} {} {} {} {} {} {} {} {} {uni_hamburg} Nipar S-20 {} {} {} {} {} {} {} {} {Chemicalbook} NITROISOPROPANE {} {} {} {} {} {} {} {} {} {uni_hamburg} Isonitropropane {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {Chemicalbook} ISONITROPROPANE {} {} {} {} {} {} {} {} {} {} {} {uni_hamburg} Dimethylnitrom
Chemical Name Translation	2-硝基丙烷
Wiswesser Line Notation	WNY1&1
LabNetwork Molecule ID	LN00196874
InChI	InChI=1S/C3H7NO2/c1-3(2)4(5)6/h3H,1-2H3

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产品应用

用作乙烯及环氧树脂涂料的特殊溶剂、火箭燃料、汽油的添加剂等，也用于有机合成

安全信息

GHS Symbol

WGK Germany3

Hazard Codes T

Hazard statements

H226 Flammable liquid and vapour 易燃液体和蒸气
H331 Toxic if inhaled 吸入中毒
H302 Harmful if swallowed 吞食有害
H350 May cause cancer 可能致癌
H412 Harmfutoaquaticlifewithlonglastingeffects 对水生生物有害并具有长期影响。
H341 Suspected of causing genetic defects 怀疑导致遗传性缺陷
H332 Harmful if inhaled 吸入有害

Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

RTECSTZ5250000

Precautionary statements

P311 Call a POISON CENTER or doctor/physician. 呼叫解毒中心或医生/医师。
P281 Use personal protective equipment as required. 使用所需的个人防护装备。
P273 Avoid release to the environment. 避免释放到环境中。
P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P201 Obtain special instructions before use. 使用前获取专门指示。
P308+P313
P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
P305+P351+P338
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P304+P340+P310
P501 Dispose of contents/container to..… 处理内容物/容器.....
P301+P312+P330
P403+P233
P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P303+P361+P353
P284 Wear respiratory protection.? 佩戴呼吸保护装置。

Signal word

Safety Statements

S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
S53 Avoid exposure - obtain special instructions before use 避免接触，使用前获得特别指示说明；
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；

Risk Statements

R20/22 Harmful by inhalation and if swallowed 吸入和不慎吞咽有害
R10 Flammable 易燃
R45 May cause cancer 可能致癌

UN Number UN 2608 3/PG 3 2608

Packing GroupIII

Hazard Class3

Storage condition Flammables area

Warnings 危化品目录(2015)

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 4277 mg/kg/16W-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Liver - tumors
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 8,1947,1987

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 207 ppm/7H/26W-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Liver - tumors
REFERENCE :
   JEPTDQ Journal of Environmental Pathology and Toxicology.  (Park Forest
   South, IL)  V.1-5(3), 1977-81(?).  For publisher information, see JEPOEC.
   Volume(issue)/page/year: 2(5),233,1979

TYPE OF TEST            : TC - Toxic concentration (other than lowest)
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 207 ppm/26W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Liver - tumors
REFERENCE :
   XPHCI* U.S. Public Health Service, Current Intelligence Bulletin. (National
   Institute for Occupational Safety and Health, 5600 Fishers Lane, Rockville,
   MD 20857)  Volume(issue)/page/year: 25APR1977

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1100 mg/kg
TOXIC EFFECTS :
   Blood - methemoglobinemia-carboxyhemoglobin
REFERENCE :
   BSPLA9 Bulletin de la Societe de Pharmacie de Lille.  (Societe de Pharmacie
   du Lille, 3, rue du Professeur Laguesse, 59045 Lille, Franch)  V.1- 1945- 
   Volume(issue)/page/year: (2),83,1972

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 75 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: AD691-490

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 20 ppm
TOXIC EFFECTS :
   Behavioral - anorexia (human)
   Gastrointestinal - hypermotility, diarrhea
   Gastrointestinal - nausea or vomiting
REFERENCE :
   INMEAF Industrial Medicine.  (Chicago, IL)  V.1-18, 1932-49.  For publisher
   information, see IOHSA5.  Volume(issue)/page/year: 16,441,1947

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 10 gm/m3/2H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single
   Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects,
   GKNT, 1982  Volume(issue)/page/year: -,94,1982

TYPE OF TEST

{ha

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 25 umol/L
REFERENCE :
   FAATDF Fundamental and Applied Toxicology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1981-  Volume(issue)/page/year:
   13,341,1989

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 7500 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE

TYPE OF TEST            : DNA damage
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 100 mg/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 391,165,1997

TYPE OF TEST            : Unscheduled DNA synthesis
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 50 mg/kg
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 10,2329,1989

TYPE OF TEST            : Micronucleus test
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 25 mg/kg
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 10,2329,1989

TYPE OF TEST            : Unscheduled DNA synthesis
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 20 mg/kg
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issu

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 2550 mg/kg
SEX/DURATION            : female 1-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
REFERENCE :
   SWEHDO Scandinavian Journal of Work, Environment and Health. (Haartmaninkatu
   1, SF-00290 Helsinki, 29, Finland)  V.1-    1975- Volume(issue)/page/year:
   7(Suppl 4),66,1981

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 2550 mg/kg
SEX/DURATION            : female 1-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - cardiovascular
   (circulatory) system
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   48,A35,1979

Restrict 危险品

其他信息

毒性分级:中毒
方法二:1.由丙烷经硝化而得。先将丙烷放在预热器内于430-450℃进行预热，然后引入内衬玻璃或二氧化硅的反应塔内。反应塔有几处可向内部丙烷气喷注75%硝酸，反应温度调节到390-440℃，压力0.69-0.86MPa，丙烷与硝酸的摩尔比为5：1，由反应塔出来的气体，经冷凝器冷却，硝基丙烷与稀硝酸即凝缩。而丙烷与气态氧化物则由回收塔回收，丙烷循环使用。所得产品为硝基甲烷10%-30%，硝基乙烷20%-25%，1-硝基丙烷25%，2-硝基丙烷40%。该品也可经丙烯硝化得到。2.由丙烯等不饱和烃经气相或液相硝化，或饱和烃液相硝化亦可制得硝基丙烷。
上游原料:硝酸 --> 硝基甲烷 --> 硝基乙烷 --> 1-硝基丙烷
用途一:萃取用溶剂。
方法一:由丙烷与硝酸在压力下反应而得。
爆炸物危险特性:遇强氧化剂可爆
MOL 文件:79-46-9.mol
储运特性:库房通风低温干燥; 与氧化剂、碱类分开存放
用途二:用作多种树脂、蜡、脂肪、染料和涂料的溶剂，合成医药、杀虫剂等的中间体。
类别:易燃液体
Acros Organics:2-硝基丙烷 2-Nitropropane, 96%(79-46-9)
下游产品:正丙胺 --> 9,10-蒽二羧醛 --> 硝基乙烷 --> N-异丙基羟胺盐酸盐 --> 1-硝基丙烷 --> 2-氨基-2-甲基-1-丙醇 --> 对甲酰基苯甲酸甲酯
海关编码:29042000
可燃性危险特性:遇明火、高温、氧化剂易燃; 燃烧产生有毒氮氧化物烟雾
用途三:用作乙烯及环氧树脂涂料的特殊溶剂、火箭燃料、汽油的添加剂等，也用于有机合成
蒸气密度:~3 (vs air)
灭火剂:干粉、二氧化碳、泡沫、1211灭火剂
蒸气压:~13 mm Hg ( 20 °C)
急性毒性:口服- 大鼠 LDL0: 720 毫克/ 公斤; 吸入-小鼠 LC50:10 克/立方米/2小时
Sigma Aldrich:79-46-9(sigmaaldrich)
{Chemic
MSDS 信息:2-硝基丙烷(79-46-9).msds
参考质量标准:FAO/WHO，1992 含量 ≥94.0% 馏程 119～122℃ 馏出量 ≥90%(V/V) 酸度(以醋酸计) 正常不挥发残渣(OT-39) ≤2mg/100ml 含水量(GT-32-1) ≤0.1%(W/W) 砷(GT-3-2) ≤3mg/kg 熏金属(GT-16-2，试样2g) ≤10mg/kg 色度(GT-1-1) ≤20号
含量分析:用装有热传导检测器的适当气相色谱仪。用1.8m×3mm不锈钢柱，填料为Porapak Q型(100/120目)。载气为氦，流量30ml/min。进样段温度250℃，柱温180℃，检测器250℃。注样量1.0/A，洗脱30min。2-硝基丙烷为主峰，约9min时洗脱，l-硝基丙烷为第二大峰，约于13min时洗脱。测出2-硝基丙烷的相对滞留时间R。，计算0.7～2.0R。之间各峰的总面积。2-硝其丙烷的峰面积应不小于总面积的94%。
职业标准:TWA 90 毫克/ 立方米)
2-硝基丙烷价格(试剂级):更新日期产品编号产品名称包装价格 2014/06/02 N0249 2-硝基丙烷 2-Nitropropane 25G 220元 2014/06/02 N0249 2-硝基丙烷 2-Nitropropane 500G 1490元 2010/06/21 157070010 2-硝基丙烷 2-Nitropropane 96% 1 KG 2432元
外观性质:无色液体。
TCI Shanghai:2-硝基丙烷 2-Nitropropane,>;95.0%(GC)(79-46-9)