(±)-Naringenin (±)-柚皮素
CAS 67604-48-2 MFCD00006844
化学结构图
SMILES: OC1C=C(O)C2C(=O)CC(OC=2C=1)C1C=CC(O)=CC=1
化学属性
| Mol. Formula | C15H12O5 |
|---|---|
| Mol. Weight | 272 |
| Melting Point | 247-250 |
| Density | 1.485 |
| TSCA | No |
别名和识别编码
| Chemical Name | (±)-Naringenin |
|---|---|
| CAS Number | 67604-48-2 |
| Synonym | (±)-2,3-二氢-5,7-二羟基-2-(4-羟基苯基)-4H-1-苯并吡喃-4-酮 4′,5,7-三羟基黄烷酮 (+/-)-5,7,4'-Trihydroxyflavanone (2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one 4',5,7-Trihydroxyflavanone 4',5,7-Trihydroxyflavanone; 5,7-Dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one; (S)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone 4',5,7-三羟基二氢黄酮 4',5,7-三羟基氟酮 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphen 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-, (S)- 4′,5,7-三羟基黄烷酮 5,7-dihydroxy-2-(4-hydroxy-phenyl)-chroman-4-one Flavanone, 4',5,7-trihydroxy- Naringenine Naringetol Salipurol 柑桔 |
| MDL Number | MFCD00006844 |
| EC Number | 266-769-1 |
| Beilstein Registry Number | 280888 |
| PubChem Substance ID | 87573466 |
| Merck Number | 6424 |
| Chemical Name Translation | (±)-柚皮素 |
| Reaxys-RN | 280888 |
信息真实价格透明
资金保障
专业采购外包团队在线服务
信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- Alphabetic, Alphabetical, Analytical Standards, Analytical/Chromatography, Chromatography, Citrus, Equisetum, Flavonoids, Glycyrrhiza, Life Sciences Standards, N, N - R, NA - NI, Natural Compounds, Phytopharma Standards, Salix, Silybum, Standards by Plant Genus, Substance Classification, Tanacetum, Thymus
- {SNA} Benzopyrans, Building Blocks, Chemical Synthesis, Chemopreventive Agents, Citrus aurantium (Seville orange), Enz
产品应用
- The aglucon of Naringin. Inhibitory mechanism of Naringenin against carcinogenic acrylamide formation and nonenzymic browning in Maillard model reactions
相关文献及参考
- Lomovskaya, N., et al.: J. Bacteriol., 181, 305 (1999),
- Beil. 8 ,503
- FT-IR 1 (2), 94:D / FT-IR 2 (2), 2502:B / FT-NMR 1 (2), 915:C / IR-Spectra (3), 905:E / IR-Spectra (2), 792:C / NMR-Reference 2 (2), 97:C / RegBook 1 (2), 1695:E / Sigma FT-IR 1 (2), 771:A / Structure Index 1 , 269:D:2
- Short: III/5b Title: Structure Data of Organic Crystals: C 14 ... C 120 Author: Schudt, E.; Weitz, G. Editor: Hellwege, K.-H.; Hellwege, A.M. Source: Landolt-Börnstein, New Series Volume: III/5b Year: 1971 ISBN: 3-540-05177-5 ISBN: 978-3-540-05177-0 Internet Resource: DOI:10.1007/b19970 RefComment: XXI, 736 pages, and VII, 890 pages. Hardcover Abstract: Volume III/5 offers a compitation as complete as possible of the space groups and lattice con-stants of all crystals which have been studied by means of X-rays, neutron and electron diffraction.
- Short: EINECS Title: EINECS (European Inventory of Existing Commercial Chemical Substances) Source: Official Journal of the European Communities Volume: C 146 A (15.06.1990) Page: 1 Year: 1990 Internet Resource: http://ecb.jrc.ec.europa.eu/esis/index.php?PGM=ein Publish_Date: 1990/06/15
安全信息
GHS Symbol
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P305+P351+P338
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36 Wear suitable protective clothing 穿戴适当的防护服；
- S37 Wear suitable gloves 戴适当手套；
- R22 Harmful if swallowed 吞咽有害
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
其他信息
- MOL 文件:480-41-1.mol
- Acros Organics:4',5,7-三羟基黄酮 4',5,7-Trihydroxyflavanone, 97%(480-41-1)
- 柚皮素价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2010/06/21 139820100 柚皮素 4',5,7-Trihydroxyflavanone 97% 10 GR 904元
- MSDS 信息:5,7-Dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one(480-41-1).msds
- 用途一:具有抗菌、抗炎、抗癌、解痉和利胆作用
- 药理作用:柚皮素是柚皮甙的甙元，属二氢黄酮类化合物，常温下为白色针状结晶(甲醇)，溶于乙醇、乙醚和苯，几乎不溶于水。盐酸镁粉反应呈樱红色，四氢硼钠反应呈红紫色，molish反应阴性。自然界中主要来源于蔷薇科植物樱花(Prunus yedoensis Mate.)花蕾，漆树科植物梗树(Amacardi-um occidentale L.)果实的核壳。 黄酮类化合物的母核结构相似，多数成分脂溶性和水溶性不甚理想，生物利用度低。通过对其结构进行修饰，引入脂溶性或水溶性较强的基团，可提高其脂溶性或水溶性，从而提高生物利用度。其结构修饰主要包括羟基的烷基化、酰化、磺化、苷化及形成金属配合物等。 柚皮素具有抗菌、抗炎、抗氧化、止咳祛痰、降血脂、抗癌抗肿瘤、解痉、清除自由基、预防和治疗肝病、抑制血小板凝结、抗粥样动脉硬化等作用，可被广泛地应用于医药、食品等领域。 1．抗菌：对金黄色葡萄球菌、大肠、痢疾和伤寒杆菌都有较强的抗菌作用。柚皮素对真菌亦有作用，1000ppm 喷于大米上能降低稻瘟菌感染40-90%，且对人和家畜没有毒性。 2．抗炎：大鼠腹腔每天注射20mg/kg，明显抑制植入羊毛球所引起的发炎过程。 3．抗癌：对大鼠白血病L1210和肉瘤均有活性。 4．解痉和利胆：为黄酮类化合物中具有较强作用者。柚皮素并有较强的增加实验动物胆汁分泌的作用。
