2-Methoxy-5-nitropyridine 2-甲氧基-5-硝基吡啶

CAS 5446-92-4 MFCD00006263

化学结构图

5446-92-4
SMILES: COc1ccc([N+](=O)[O-])cn1

化学属性

Mol. FormulaC6H6N2O3
Mol. Weight154.12
Melting Point104-108 °C
Density1.422
Flash Point130 ºC
Solubility不溶
Boiling Point277.46 °C at 760 mmHg

别名和识别编码

Chemical Name2-Methoxy-5-nitropyridine
CAS Number5446-92-4
Alfabeta NameMETHOXYNITROPYRIDINE 25---
MDL NumberMFCD00006263
Synonym 2-Methoxy-5-nitropyridine {LY} 2-Methoxy-5-nitropyridine {} {LY} 2-Methoxy-5-nitropyridine {} {} {LY} 2-Methoxy-5-nitropyridine {} {} {} {LY} 2-Methoxy-5-nitropyridine {} {} {} {} {LY} 2-Methoxy-5-nitropyridine {} {} {} {} {} {LY} 2-Methoxy-5-nitropyridine {} {} {} {} {} {} {LY} 2-Methoxy-5-nitropyridine {} {} {} {} {} {} {} {LY} 2-Methoxy-5-nitropyridine {} {} {} {} {} {} {} {} {LY} 2-Methoxy-5-nitropyridine {} {} {} {} {} {} {} {} {} {LY} 2-Methoxy-5-nitropyridine {} {} {} {} {} {} {} {} {} {} {LY} 2-Methoxy-5-nitropyridine {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Methoxy-5-nitropyridine {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Methoxy-5-nitropyridine {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Methoxy-5-nitropyridine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Methoxy-5-nitropyridine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Methoxy-5-nitropyridine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
EC Number226-661-7
Beilstein Registry Number126991
PubChem Substance ID87573261
Reaxys-RN126991
Chemical Name Translation2-甲氧基-5-硝基吡啶
InChIKeyWUPLOZFIOAEYMG-UHFFFAOYSA-N
LabNetwork Molecule IDLN00120103
Canonical SMILESCOC1=CC=C([N+]([O-])=O)C=N1
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • {SNA} Building Blocks, C6, Chemical Synthesis, Heterocyclic Building Blocks, Pyridines
  • {uni_hamburg} no charge; nitrogen heterocycle; aromatic; 6RingOnly; 6ring; 1fragment

相关文献及参考

  • Short: EINECS Title: EINECS (European Inventory of Existing Commercial Chemical Substances) Source: Official Journal of the European Communities Volume: C 146 A (15.06.1990) Page: 1 Year: 1990 Internet Resource: http://ecb.jrc.ec.europa.eu/esis/index.php?PGM=ein Publish_Date: 1990/06/15
  • Short: III/35E Title: Nuclear Magnetic Resonance (NMR) Data: Chemical Shifts for Oxygen-17 Author: Duddeck, H.; Toth, G.; Simon, A. Editor: Gupta, R.R.; Lechner, M.D. Source: Landolt-Börnstein, New Series Volume: III/35E Year: 2002 Keyword: Alipathic and Aromatic hydrocarbons; Coupling constant j; Nuclear Magnetic Resonance; chemical shifts δ ISBN: 3-540-42501-2 ISBN: 978-3-540-42501-4 Internet Resource: DOI:10.1007/b92953 RefComment: VII, 230 pages. With CD-ROM., Hardcover Abstract: This volume provides a comprehensive and evaluated compilation of nuclear magnetic resonance data. Chemical shifts and coupling constants of boron-11 and phosphorus-31 (subvol. A), fluorine-19 and nitrogen-15 (subvol. B), hydrogen-1 (subvol. C), carbon-13 (subvol. D), and oxygen-17 (subvol. E) compounds are tabulated together with the gross- and structure formulas and the most readily available solvents. Due to the large amount of the data merely chemical shifts are presented in the printed versions, and all the data, chemical shifts and coupling constants are provided on CD-ROM's.

安全信息

Warnings IRRITANT
Signal word Warning
GHS Symbol
WGK Germany3
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
  • S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P352+P332+P313+P362+P364
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P332+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes Xi
Storage condition Store at room temperature {LY} Store at room temperature {} {LY} Store at room temperature {} {} {LY} Store at room temperature {} {} {} {LY} Store at room temperature {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}

其他信息

  • 5-硝基-2-甲氧基吡啶价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 M1304 2-甲氧基-5-硝基吡啶 2-Methoxy-5-nitropyridine 25G 690元 2010/06/21 125990250 5-硝基-2-甲氧基吡啶 2-Methoxy-5-nitropyridine 97% 25 GR 417元
  • 用途一:用于有机合成。该品还原得到5-氨基-2-甲氧基吡啶，是药物的中间体。例如，用来生产抗疟急救药咯萘啶。
  • MSDS 信息:2-Methoxy-5-nitropyridine(5446-92-4).msds
  • TCI Shanghai:2-甲氧基-5-硝基吡啶 2-Methoxy-5-nitropyridine,>;98.0%(GC)(5446-92-4)
  • Acros Organics:2-甲氧基-5-硝基吡啶 2-Methoxy-5-nitropyridine, 97%(5446-92-4)
  • 上游原料:甲醇 --> 甲醇钠 --> 2-氯-5-硝基吡啶
  • MOL 文件:5446-92-4.mol
  • 检测方法:HPLC,NMR
  • 方法一:由2-氯-5-硝基吡啶经醚化反应而得。将甲醇钠在搅拌下滴加入2-氯-5-硝基吡啶和甲醇的混合液中，加硫1h后在碎冰中析出晶体。过滤，干燥，用甲醇重结晶即得成品。收率为92%。
  • 下游产品:5-氨基-2-甲氧基吡啶
  • Sigma Aldrich:5446-92-4(sigmaaldrich)

系列性分类

  1. C6 - Pyridines
  1. C6 to C7 - Pyridines
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Pyridines 吡啶

相关产品推荐