2-Morpholinoethanol 2-吗啉乙醇
CAS 622-40-2 MFCD00006180
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分类
- Heterocycles
- {SNA} Building Blocks, C4 to C10, Chemical Synthesis, Heterocyclic Building Blocks, Morpholines/Thiomorpholines
- {uni_hamburg} no charge; oxygen heterocycle; nitrogen heterocycle; alicycle; 6RingOnly; 6ring; alcohol; ether; 1fragment
- Intermediates,
产品应用
- 4-(2-Hydroxyethyl)morpholine is a morphiline derivative used in the preparation of ester prodrugs of naproxen. 4-(2-Hydroxyethyl)morpholine was also shown to induce repair in rat hepatocyte primary cu
相关文献及参考
- Short: III/47
- Conaway, C.C. et al.: Mutat. Res. Gen. Toxicol. Test., 136, 153 (1984); Tsai, S.-W. et al.: Chem. Technol. Biotechnol., 74, 751 (1999);
- Short: III/38B
- Beilstein:27,7
安全信息
GHS Symbol
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
- S36 Wear suitable protective clothing 穿戴适当的防护服;
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- R37/38 Irritating to respiratory system and skin 对呼吸系统和皮肤有刺激性
- R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P305+P351+P338
- P305+P351+P338+P337+P313
- P332+P313
- P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 3600 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CANCAR Cancer (Philadelphia). (Lippincott/Harper, Journal Fulfillment Dept., 2350 Virginia Ave., Hagerstown, MD 21740) V.1- 1948- Volume(issue)/page/year: 2,1055,1949
TYPE OF TEST
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 5500 mg/kg TOXIC EFFECTS : Gastrointestinal - other changes REFERENCE : ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 1,16,1990
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 2650 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 109,108,1957
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : >16 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 1,16,1990
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TYPE OF TEST : Unscheduled DNA synthesis TEST SYSTEM : Rodent - rat Liver DOSE/DURATION : 1 gm/L REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 136,153,1984
其他信息
- 下游产品:N-(2-氯乙基)吗啉盐酸盐
- 方法一:由吗啉与环氧乙烷加成而得。将环氧乙烷气体通入吗啉中反应,温度控制在20℃以下,通毕,保温半小时。加热蒸除水分至尽,残留液减压蒸馏,收集122-126℃(1.33kPa)馏分,得吗啉乙醇。
- 2-吗啉乙醇价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 H0244 4-(2-羟乙基)吗啉 4-(2-Hydroxyethyl)morpholine 25ML 140元 2014/06/02 H0244 4-(2-羟乙基)吗啉 4-(2-Hydroxyethyl)morpholine 500ML 765元 2010/06/21 121180050 2-吗啉乙醇 N-(2-Hydroxyethyl)morpholine 99% 5 GR 209元
- 用途一:用于有机合成。
- Sigma Aldrich:622-40-2(sigmaaldrich)
- MSDS 信息:N-羟乙基吗啉(622-40-2).msds
- Acros Organics:N-(2-羟基乙基)吗啉 N-(2-Hydroxyethyl)morpholine, 99%(622-40-2)
- 图谱信息:2-吗啉乙醇(622-40-2)核磁图( 13 CNMR) 2-吗啉乙醇(622-40-2)红外图谱(IR2) 2-吗啉乙醇(622-40-2)红外图谱(IR1) 2-吗啉乙醇(622-40-2)核磁图( 1 HNMR) 2-吗啉乙醇(622-40-2)质谱(MS)
- 和水混溶。
- Alfa Aesar:4-2-羟乙基吗啉,99% 4-(2-Hydroxyethyl)morpholine, 99%(622-40-2)
- F:10-23
- 外观性质:无色液体。
- TCI Shanghai:4-羟乙基吗啉 4-(2-Hydroxyethyl)morpholine,>;99.0%(GC)(622-40-2)
- MOL 文件:622-40-2.mol
- 海关编码:29349990