6-Methyluracil 6-甲基脲嘧啶
CAS 626-48-2 MFCD00006028
信息真实价格透明
资金保障
专业采购外包团队在线服务
信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- Bases & Related Reagents
- {SNA} Building Blocks, C4 to C5, Chemical Synthesis, Heterocyclic Building Blocks, Pyrimidines
- Nucleotides
- {uni_hamburg} no charge; nitrogen heterocycle; aromatic; 6RingOnly; 6ring; 1fragment
产品应用
- 生化研究。
相关文献及参考
- [2]. Taran IP, et, al. [The antiradiation action of 6-methyluracil]. Radiobiologiia. Mar-Apr 1993;33(2):285-90.
- Merck: 14,6133
- Merck: 14,6133 Beilstein:24,342
- Short: EINECS
- Short: III/20a
- Short: IV/20C
- [1]. Cromby CH, et, al. 6-Methyluracil excretion in 2-methylacetoacetyl-CoA thiolase deficiency and in two children with an unexplained recurrent ketoacidaemia. J Inherit Metab Dis. 1994;17(1):81-4.
- [1]. Cromby CH, et, al. 6-Methyluracil excretion in 2-methylacetoacetyl-CoA thiolase deficiency and in two children with an unexplained recurrent ketoacidaemia. J Inherit Metab Dis. 1994;17(1):81-4.
- [2]. Taran IP, et, al. [The antiradiation action of 6-methyluracil]. Radiobiologiia. Mar-Apr 1993;33(2):285-90.
安全信息
GHS Symbol
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
- R62 Possible risk of impaired fertility 有削弱生殖能力的危险
- R63 Possible risk of harm to the unborn child 可能危害未出生婴儿
- P201 Obtain special instructions before use. 使用前获取专门指示。
- P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P281 Use personal protective equipment as required. 使用所需的个人防护装备。
- P308+P313
- P405 Store locked up. 上锁保管。
- P501 Dispose of contents/container to..… 处理内容物/容器.....
- H361 Suspected of damaging fertility or the unborn child 怀疑对生育能力或未出生婴儿造成伤害
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 18 gm/kg/52W-C TOXIC EFFECTS : Tumorigenic - neoplastic by RTECS criteria Endocrine - thyroid tumors REFERENCE : VOONAW Voprosy Onkologii. Problems of Oncology. For English translation, see PONCAU. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-10, 1928-37; V.1- 1955- Volume(issue)/page/year: 8(10),49,1962
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - species unspecified DOSE/DURATION : 2 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 48,186,1985
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 2700 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 27,112,1993
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >7500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 44,56,1955
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 64500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : LONZA# Personal Communication from LONZA Ltd., CH-4002, Basel, Switzerland Volume(issue)/page/year: 03FEB1981
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE : 2 gm/kg SEX/DURATION : female 10 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Embryo or Fetus - fetal death Reproductive - Specific Developmental Abnormalities - urogenital system REFERENCE : BEXBAN Bulletin of Experimental Biology and Medicine (English Translation). Translation of BEBMAE. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) V.41- 1956- Volume(issue)/page/year: 66,1382,1968
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE : 20 mg/kg SEX/DURATION : female 4 day(s) pre-mating TOXIC EFFECTS : Reproductive - Maternal Effects - uterus, cervix, vagina REFERENCE : JSICAZ Journal of Scientific and Industrial Research, Section C: Biological Sciences. (New Delhi, India) V.14-21, 1955-62. For publisher information, see IJEBA6. Volume(issue)/page/year: 19,264,1960
其他信息
- Sigma Aldrich:626-48-2(sigmaaldrich)
- 方法一:由尿素与乙酰乙酸乙酯缩合,再经环合而得。
- MOL 文件:626-48-2.mol
- 海关编码:29335995
- 用途二:用于有机合成及生化研究工作。该品是药物潘生丁的中间体。
- Alfa Aesar:6-甲基尿嘧啶,97% 6-Methyluracil, 97%(626-48-2)
- 水溶液pH13。300℃以上分解。最大吸收波长277nm(logε3.83)。
- 上游原料:尿素 --> 乙酰乙酸甲酯
- 图谱信息:2,4-二羟基-6-甲基嘧啶(626-48-2)核磁图( 1 HNMR) 2,4-二羟基-6-甲基嘧啶(626-48-2)质谱(MS) 2,4-二羟基-6-甲基嘧啶(626-48-2)红外图谱(IR2) 2,4-二羟基-6-甲基嘧啶(626-48-2)红外图谱(IR1)
- MSDS 信息:2,4-Dihydroxy-6-methylpyrimidine(626-48-2).msds
- TCI Shanghai:6-甲基脲嘧啶 6-Methyluracil,>;98.0%(T)(626-48-2)
- 2,4-二羟基-6-甲基嘧啶价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 M0454 6-甲基脲嘧啶 6-Methyluracil 500G 1590元 2014/06/02 M0454 6-甲基脲嘧啶 6-Methyluracil 25G 169元 2010/06/21 114981000 2,4-二羟基-6-甲基嘧啶 2,4-Dihydroxy-6-methylpyrimidine 97% 100 GR 282元
- Acros Organics:2,4-二羟基-6-甲基嘧啶 2,4-Dihydroxy-6-methylpyrimidine, 97%(626-48-2)
- 2,4-二羟基-6-甲基嘧啶价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/04/16 M0454 6-甲基脲嘧啶 6-Methyluracil 500G 1720元 2011/04/16 M0454 6-甲基脲嘧啶 6-Methyluracil 25G 182元 2010/06/21 114981000 2,4-二羟基-6-甲基嘧啶 2,4-Dihydroxy-6-methylpyrimidine 97% 100 GR 282元
- 检测方法:HPLC,NMR
- 用途一:用于医药工业,主要用于心血管药物潘生丁的合成
- 下游产品:乳清酸 --> 2,4-二羟基-6-甲基-5-硝基嘧啶 --> 6-甲基-4-(二甲氨基)-2-氯嘧啶 --> 2,4-二氯-5-硝基-6-甲基嘧啶 --> 乳清酸钾 --> 6-羰基-2,4-二氢嘧啶一钠盐 --> 6-甲酰尿嘧啶