• 原料直供
• 试剂商城
• 直接询价

分类

• {SNA} Building Blocks, C8 to C9, Chemical Synthesis, Heterocyclic Building Blocks, Thiazoles
• {uni_hamburg} no charge; sulfur heterocycle; nitrogen heterocycle; carbocycle; aromatic; large ring; fused rings; 5ring; 6ring; 9ring; ether; 1fragment

相关文献及参考

• Short: III/35D3 Title: Nuclear Magnetic Resonance (NMR) Data: Chemical Shifts for Carbon-13, Part 3: Heterocycles Author: Gupta, R.R.; Jain, M.; Lechner, M.D.; Mikhova, B.M. Editor: Gupta, R.R.; Lechner, M.D. Source: Landolt-Börnstein, New Series Volume: III/35D3 Year: 2007 Keyword: C-13; NMR; carbon-13; chemical shifts; coupling constants; heterocycles; nuclear magnetic resonance ISBN: 978-3-540-29731-4 ISBN: 3-540-29731-6 Internet Resource: DOI: 10.1007/978-3-540-47067-0 RefComment: VIII, 342 p., 1 illus., Hardcover RefComment: Written for Science and engineers in the fields of physics, chemistry and physical chemistry who inted to use NMR to study the structure and the binding of molecules Abstract: Nuclear Magnetic Resonance (NMR) is based on the fact that certain nuclei exhibit a magnetic moment, orient by a magnetic field, and absorb characteristic frequencies in the radiofrequency part of the spectrum. NMR is now a leading technique and a powerful tool for the investigation of the structure and interaction of molecules. The present Landolt-Börnstein volume III/35 Nuclear Magnetic Resonance (NMR) Data is therefore of major interest to all scientists and engineers who use NMR to study the structure and the binding of molecules. Volume III/35 "NMR-Data" is divided into several subvolumes and parts. Subvolume III/35A contains the nuclei B-11 and P-31, subvolume III/35B contains the nuclei F-19 and N-15, subvolume III/35C contains the nucleus H-1, subvolume III/35D contains the nucleus C-13, subvolume III/35E contains the nucleus O-17, and subvolume III/35G contains the nucleus Se-77. More nuclei are planned for future volumes.
• Short: EINECS Title: EINECS (European Inventory of Existing Commercial Chemical Substances) Source: Official Journal of the European Communities Volume: C 146 A (15.06.1990) Page: 1 Year: 1990 Internet Resource: http://ecb.jrc.ec.europa.eu/esis/index.php?PGM=ein Publish_Date: 1990/06/15

安全信息

GHS Symbol

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 140 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 105,486,1952

TYPE OF TEST            : Unscheduled DNA synthesis
TEST SYSTEM             : Rodent - rat Liver
DOSE/DURATION           : 10 umol/L
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 3,11,1981

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 600 nmol/L
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 3,11,1981

其他信息

• 用途一:用作阳离子染料中间体
• 图谱信息:2-氨基-6-甲氧基苯并噻唑(1747-60-0)红外图谱(IR1) 2-氨基-6-甲氧基苯并噻唑(1747-60-0)红外图谱(IR2) 2-氨基-6-甲氧基苯并噻唑(1747-60-0)质谱(MS)
• Hazard Note:Irritant
• 下游产品:阳离子蓝X-GRRL --> 阳离子暗黄2RL --> 6-甲氧基-3-甲基苯并噻唑腙-[2] --> 碱性兰162
• Sigma Aldrich:1747-60-0(sigmaaldrich)
• 2-氨基-6-甲氧基苯并噻唑价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 A0715 2-氨基-6-甲氧基苯并噻唑 2-Amino-6-methoxybenzothiazole 25G 403元 2014/06/02 A0715 2-氨基-6-甲氧基苯并噻唑 2-Amino-6-methoxybenzothiazole 500G 1940元 2010/06/21 172022500 2-氨基-6-甲氧基苯并噻唑 2-Amino-6-methoxybenzothiazole 98% 250 GR 3310元
• 用途二:染料中间体。用于制造阳离子艳蓝RL、阳离子黄2RL；由它制备6-甲氧基-3-甲基苯并噻唑腙，进而生产阳离子黄GL等。
• MOL 文件:1747-60-0.mol
• 检测方法:HPLC
• 用途三:染料中间体，用于制造阳离子艳蓝RL、阳离子黄2RL；由它制备6-甲氧基-3-甲基苯并噻唑腙，进而生产阳离子黄GL等。
• 上游原料:氨基苯 --> Α-球蛋白 --> 对甲氧基苯胺 --> 硫氰酸钠 --> 刚果红试纸 --> 二氯化二硫 --> 工业盐酸 --> 对甲氧基苯基硫脲 --> 酚酞 --> 对甲氧基苯硫脲
• Acros Organics:2-氨基-6-甲氧基苯并噻唑 2-Amino-6-methoxybenzothiazole, tech., 90%(1747-60-0)
• Alfa Aesar:2-氨基-6-甲氧基苯并噻唑,98% 2-Amino-6-methoxybenzothiazole, 98%(1747-60-0)
• TCI Shanghai:2-氨基-6-甲氧基苯并噻唑 2-Amino-6-methoxybenzothiazole,>;98.0%(T)(1747-60-0)
• 方法一:先由对氨基苯甲醚盐酸盐和硫氰酸钠反应，得到对甲氧基苯基硫脲，再与氯化硫闭环而得。工艺过程如下：（1）在搪玻璃锅中加入水，加热到60℃，搅拌下慢慢加入对氨基苯甲醚，在60-65℃搅拌30min使其完全溶解。用30%工业盐酸调整溶液酸度刚果红试纸呈微蓝色，维持10min，再加硫氰酸钠，加热，慢慢升温到105℃，在105℃左右回流24h。然后冷到25℃过滤。滤饼用水洗涤、干燥，得对甲氧基苯基硫脲。（2）将无水氯仿吸入干燥的搪玻璃锅中，搅拌下加入干燥的对甲氧基苯硫脲。加热到60-62℃，蒸出部分氯仿及原料中的水。然后冷却到25℃，逐渐加入氯化硫。加完后，在30℃搅拌1h，升温到43-45℃反应4h。反应中产生氯化氢气体，通过吸收系统吸收。再于62-64℃回流反应10h。然后冷却到60℃以下，将物料压到装有烟囱灰（代活性炭）和水的酸性蒸馏锅中，用直接蒸汽蒸馏回收氯仿，直到温度95℃，并维持15min。氯仿回收后停止蒸馏，冷到90℃，加水调整体积，再加冰冷却到45℃，细流加入30%液碱，调整pH值至4-5，搅拌15min。抽滤，将滤液加热到60℃，用30%液碱进行碱析酚酞呈微红色。抽滤，所得滤饼即为成品。熔点160-163℃收率85%。
• 外观性质:白色晶体。熔点：165-167℃沸点：240°C
• MSDS 信息:6-Methoxy-2-aminobenzothiazole(1747-60-0).msds