3-Maleimidobenzoic Acid N-Hydroxysuccinimide Ester 3-马来酰亚胺基苯甲酸琥珀酰亚胺酯
CAS 58626-38-3 MFCD00005514
化学结构图
SMILES: O=C(ON1C(=O)CCC1=O)C1=CC(=CC=C1)N1C(=O)C=CC1=O
化学属性
| Mol. Formula | C15H10N2O6 |
|---|---|
| Mol. Weight | 314.25 |
| Melting Point | 175-182 |
别名和识别编码
| Chemical Name | 3-Maleimidobenzoic Acid N-Hydroxysuccinimide Ester |
|---|---|
| CAS Number | 58626-38-3 |
| Synonym | 3-马来酰亚胺基苯甲酸琥珀酰亚胺酯 m-Maleimidobenzoyl-N-hydroxysuccinimide MBS NSC 294786 3-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)benzoic Acid 2,5-Dioxo-1-pyrrolidinyl Ester |
| MDL Number | MFCD00005514 |
| PubChem Substance ID | 87575905 |
| Beilstein Registry Number | 1505254 |
| Reaxys-RN | 1505254 |
| EC Number | 261-368-8 |
| Chemical Name Translation | 3-马来酰亚胺基苯甲酸琥珀酰亚胺酯 |
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分类
- {SNA} Chemical Biology, Chemical Synthesis, Crosslinkers, Crosslinking, Crosslinking Reagents, Heterobifunctional Cross-Linking Reagents, Heterobifunctional Crosslinking Reagents, Linkers and Crosslinkers, Protein Modification, 分子生物学, 蛋白质相互作用, 蛋白质组学, 蛋白质结构
- {SNA} Chemical Biology, Chemical Synthesis, Crosslinkers, Crosslinking, Crosslinking Reagents, Heterobifunctional Cross-Linking Reagents, Heterobifunctional Crosslinking Reagents, Linkers and Crosslinkers, Protein Interaction, Protein Modification, Protein Structural Analysis,
产品应用
- A heterobifunctional coupling reagent useful for forming enzyme immunoconjugates. The reactive groups are the NHS ester and maeimide.
相关文献及参考
- O?Sullivan, M.J., et al.: Anal. Biochem., 100, 100 (1979),
- Kitagawa, T. and Aikawa, T., Enzyme coupled immunoassay of insulin using a novel coupling reagent. J. Biochem. Tokyo 79 , 233-236, (1976) 摘要
- O'Sullivan, M.J. et al., Comparison of two methods of preparing enzyme-antibody conjugates: application of these conjugates for enzyme immunoassay. Anal. Biochem. 100 , 100-108, (1979)
- Corp MSDS 1 (2), 2184:D / FT-IR 2 (2), 3071:D / RegBook 1 (2), 2079:A / Sigma FT-IR 1 (2), 690:D / Structure Index 1 , 329:E:1
安全信息
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P302+P352+P332+P313+P362+P364
- P305+P351+P338
- P305+P351+P338+P337+P313
- P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
GHS Symbol
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36 Wear suitable protective clothing 穿戴适当的防护服；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
