CAS 2466-76-4 MFCD00005287-1-(1H-Imidazol-1-yl)ethanone N-乙酰基咪唑 TAO{mole}

1-(1H-Imidazol-1-yl)ethanone N-乙酰基咪唑

CAS 2466-76-4 MFCD00005287

化学结构图

SMILES: CC(=O)n1ccnc1

化学属性

Mol. Formula	C5H6N2O
Mol. Weight	110.11
Melting Point	99-105°C
TSCA	Yes
Density	1.14
Appearance	无色结晶。熔点103-105℃。极易水解。
Stability	对湿度敏感
Boiling Point	222.0±23.0°C at 760 mmHg

别名和识别编码

Chemical Name	1-(1H-Imidazol-1-yl)ethanone
Synonym	1-Acetylimidazole {LY} 1-Acetylimidazole {} {LY} 1-Acetylimidazole {} {} {LY} 1-Acetylimidazole {} {} {} {LY} 1-Acetylimidazole {} {} {} {} {LY} 1-Acetylimidazole {} {} {} {} {} {LY} 1-Acetylimidazole {} {} {} {} {} {} {LY} 1-Acetylimidazole {} {} {} {} {} {} {} {LY} 1-Acetylimidazole {} {} {} {} {} {} {} {} {LY} 1-Acetylimidazole {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1-Acetylimidazole {} {} {} {} {} {} {} {} {} {} {LY} 1-Acetylimidazole {} {} {} {} {} {} {} {} {} {} {} {LY} 1-Acetylimidazole {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1-Acetylimidazole {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1-Acetylimidazole {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1-Acetylimidazole {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1-Acetylimidazole {} {} {} {} {} {} {} {} {} {} {}
MDL Number	MFCD00005287
PubChem Substance ID	17174
Beilstein Registry Number	108425
CAS Number	2466-76-4
EC Number	219-577-7
Reaxys-RN	108425
Chemical Name Translation	N-乙酰基咪唑
Wiswesser Line Notation	T5N CNJ AV1
LabNetwork Molecule ID	LN00222302
InChI	InChI=1S/C5H6N2O/c1-5(8)7-3-2-6-4-7/h2-4H,1H3
Canonical SMILES	CC(N1C=CN=C1)=O

信息真实价格透明资金保障专业采购外包团队在线服务

品牌质保精细包装现货库存一流品牌服务

产品应用

酪氨酸残基的乙酰化试剂。用于环状咪唑衍生物的合成

安全信息

WGK Germany3

RTECSNI3400000

Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

Safety Statements

Risk Statements

R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

Storage condition 2-8°C {LY} 2-8°C Moisture Sensitive Store at 0 {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {

Signal word Warning

GHS Symbol

Precautionary statements

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 50 mg/kg/I
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
REFERENCE :
   JNCIAM Journal of the National Cancer Institute.  (Washington, DC)  V.1-60,
   1940-78.  For publisher information, see JJIND8.  Volume(issue)/page/year:
   54,495,1975

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 250 mg/kg
TOXIC EFFECTS :
   Immunological Including Allergic - decreased immune response
REFERENCE :
   StoGD# Personal Communication from G.D. Stoner, Dept. of Community Medicine,
   School of Medicine, Univ. of California, La Jolla, CA 92037, May 25, 1975 
   Volume(issue)/page/year: 27MAY1975

其他信息

遇水分解，溶于乙酸异丙烯酯。极易水解
方法一:咪唑与乙酸异丙烯酯反应在50毫升圆烧瓶中，加入0.2g(0.03mol)咪唑，20ml乙酸异丙烯酯和几滴浓硫酸。将混合物在60℃保温1h。蒸馏除去少量的乙酸异丙烯酯和丙酮。剩余物用水碳酸钠处理。倾出液体。在空气浴中蒸发至干。得粗品3.1g，产率94%，熔点93-96℃。现经乙酸异丙烯酯重结晶，熔点达到101.5102.5℃。
用途二:作乙酰化试剂，供生化研究用。
毒性分级:高毒
急性毒性:腹腔-小鼠 LDL0: 250 毫克/公斤
用途一:用作医药中间体
类别:有毒物品
图谱信息:1-乙酰基咪唑(2466-76-4)质谱(MS) 1-乙酰基咪唑(2466-76-4)核磁图( 1 HNMR) 1-乙酰基咪唑(2466-76-4)红外图谱(IR1)
MOL 文件:2466-76-4.mol
上游原料:乙酸异丙烯酯
Acros Organics:1-乙酰咪唑 1-Acetylimidazole, 98%(2466-76-4)
TCI Shanghai:N-乙酰基咪唑 N-Acetylimidazole,>;98.0%(GC)(T)(2466-76-4)
灭火剂:干粉、泡沫、砂土、二氧化碳, 雾状水
F:10-21
MSDS 信息:NAI(2466-76-4).msds
Sigma Aldrich:2466-76-4(sigmaaldrich)
Alfa Aesar:N-乙酰基咪唑,98% 1-Acetylimidazole, 98%(2466-76-4)
储运特性:库房通风低温干燥
敏感性:Moisture Sensitive
1-乙酰基咪唑价格(试剂级):更新日期产品编号产品名称包装价格 2011/08/23 xw010108 1-乙酰咪唑 100g 800元 2011/04/16 A0694 N-乙酰基咪唑 N-Acetylimidazole 25G 342元 2011/04/16 A0694 N-乙酰基咪唑 N-Acetylimidazole 500G 3180元
可燃性危险特性:可燃; 加热分解释放有毒氮氧化物烟雾