2,3-Dimercapto-1-propanol 2,3-二巯基-1-丙醇
CAS 59-52-9 MFCD00004864
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信息真实价格透明
资金保障
专业采购外包团队在线服务
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分类
- {SNA} Alphabetical Index of Analytical Standards, Analytical Reagents, Analytical Standards, Analytical/Chromatography,
- {SNA} Building Blocks, Chemical Synthesis, Organic Building Blocks, Sulfur Compounds, Thiols/Mercaptans
- Alphabetic, Analytical Reagents, Analytical Standards, Analytical/Chromatography, Complexometric Titration Reagents (EDTA Titration), D, DID - DIN, Masking Agents, Spe
- {SNA} Complexometric Titration Reagents (EDTA Titration), Masking Agents, Spectroscopy, Titration, UV/Vis Reagents, UV/Visible (UV/VIS) Spectroscopy, 分析/色谱, 分析试剂
产品应用
- 本品为解毒药,主要用于含砷或含汞毒物的解毒,也可用于某些重金属(如铋、锑、镉等)的中毒。2,3-二巯基丙醇与路易斯气反应,生成稳定、不溶而无毒的砷化合物。因此被称为英国抗路易斯气剂。与二巯基丙醇解毒作用相似的品种是二巯基丁二酸钠(C4H4Na2O4S2)。也用作光度法测定铜。
相关文献及参考
- 1. J.F. Danielli et al. Biochem. J. 41 , 325, (1947) 摘要
- 2. F.W. Oehme Toxicity of Heavy Metals in the Environment New York , (1979)
- 3. J.C. Majumdar, B.C. Haldar Radiochem. Radioanal. Lett. 48 , 247, (1981)
- 4. E. Casassas Chimie analyt. 47 , 419, (1965)
- Merck 14 ,3209
- Beil. 1 ,IV,2770
- Aldrich MSDS 1 , 726:D / Corp MSDS 1 (1), 1303:D / FT-IR 1 (1), 262:D / FT-IR 2 (1), 417:C / FT-NMR 1 (1), 423:C / IR-Spectra (3), 155:B / IR-Spectra (2), 138:H / NMR-Reference 2 (1), 230:A / RegBook 1 (1), 283:B / Sax 6 , 343 / Sigma FT-IR 1 (2), 482:D / Structure Index 1 , 38:D:8 / Vapor Phase 3 , 345:D
- Short: III/38B Title: Refractive Indices of Organic Liquids Author: Wohlfarth, Ch.; Wohlfarth, B. Editor: Lechner, M.D. Source: Landolt-Börnstein, New Series Volume: III/38B Year: 1996 Keyword: organic compounds; refractive index; liquids ISBN: 3-540-60596-7 ISBN: 978-3-540-60596-6 Internet Resource: DOI:10.1007/b85533 RefComment: VII, 4210 pages, Hardcover Abstract: Volume III/38 Optical Constants provides critically evaluated data on refractive indices of inorganic and organic liquids and their wavelength dependence (dispension). Part A contains the inorganic, organometallic, and organononmetallic liquids, and the binary liquid mixtures (about 900 pure substances and their mixtures). Part B contains data of more than 7600 organic liquids.
- Short: IV/18B Title: Viscosity of Pure Organic Liquids and Binary Liquid Mixtures: Pure Organic Liquids Author: Wohlfarth, Ch.; Wohlfarth, B. Editor: Lechner, M.D. Source: Landolt-Börnstein, New Series Volume: IV/18B Year: 2001 Keyword: organic compounds; viscosity; liquids; mixtures Internet Resource: DOI:10.1007/b68240 RefComment: VII, 409 pages.
- Short: IV/20A Title: Vapor Pressure and Antoine Coeffic
安全信息
GHS Symbol
- H301 Toxic if swallowed 吞食有毒
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- P362+P364
- P301+P316
- P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
- P405 Store locked up. 上锁保管。
- P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
- P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
- P501 Dispose of contents/container to..… 处理内容物/容器.....
- P403+P233
- P337+P317
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P302+P352
- P304+P340
- P319
- P305+P351+P338
- P332+P317
- P330 Rinse mouth. 漱口
- P264+P265
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- R22 Harmful if swallowed 吞咽有害
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
- S36 Wear suitable protective clothing 穿戴适当的防护服;
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 50 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : BIJOAK Biochemical Journal. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1906- Volume(issue)/page/year: 41,325,1947
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 56 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#04985
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 25 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intramuscular SPECIES OBSERVED : Human DOSE/DURATION : 3 mg/kg TOXIC EFFECTS : Blood - hemorrhage Skin and Appendages - dermatitis, other (after systemic exposure) REFERENCE : SCIEAS Science. (American Assoc. for the Advancement of Science, 1333 H St., NW, Washington, DC 20005) V.1-
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TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE : 100 mg/kg SEX/DURATION : female 12 day(s) after conception TOXIC EFFECTS : Reproductive - Specific Developmental Abnormalities - musculoskeletal system REFERENCE : ANREAK Anatomical Record. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1906/08- Volume(issue)/page/year: 135,261,1959
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE : 200 mg/kg SEX/DURATION : female 12-13 day(s) after conception TOXIC EFFECTS : Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) REFERENCE : ANREAK Anatomical Record. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1906/08- Volume(issue)/page/year: 135,261,1959
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE : 100 mg/kg SEX/DURATION : female 11 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Embryo or Fetus - fetal death REFERENCE : ANREAK Anatomical Record. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1906/08- Volume(issue)/page/year: 135,261,1959
其他信息
- TCI Shanghai:2,3-二巯基-1-丙醇 2,3-Dimercapto-1-propanol,>;95.0%(GC)(T)(59-52-9)
- F:8-9-13-23
- MOL 文件:59-52-9.mol
- Alfa Aesar:2,3-二巯基丙醇,97% 2,3-Dimercaptopropanol, 97%(59-52-9)
- 灭火剂:干粉,泡沫,沙土,二氧化碳, 雾状水
- 类别:有毒物品
- MSDS 信息:二巯基丙醇(59-52-9).msds
- Acros Organics:2,3-二巯基-1-丙醇 2,3-Dimercapto-1-propanol, 97.0-100.5%(59-52-9)
- 用途二:本品为解毒药,主要用于含砷或含汞毒物的解毒,也可用于某些重金属(如铋、锑、镉等)的中毒。2,3-二巯基丙醇与路易斯气反应,生成稳定、不溶而无毒的砷化合物。因此被称为英国抗路易斯气剂。与二巯基丙醇解毒作用相似的品种是二巯基丁二酸钠(C4H4Na2O4S2)。也用作光度法测定铜。
- 海关编码:29309070
- 急性毒性:腹腔-大鼠 LD50: 105 毫克/公斤; 口服-小鼠 LD50: 217 毫克/公斤
- 用途一:本品为解毒药,主要用于含砷或含汞毒物的解毒,也可用于某些重金属(如铋、锑、镉等)的中毒。2,3-二巯基丙醇与路易斯气反应,生成稳定、不溶而无毒的砷化合物。因此被称为英国抗路易斯气剂。与二巯基丙醇解毒作用相似的品种是二巯基丁二酸钠(C4H4Na2O4S2)。这是我国创制的新解毒药,解毒效力比二巯基丙醇强,且毒性较小。二巯基丙醇对鼠皮下注射LD50为86.7毫克/公斤。
- 外观性质:粘稠的油状液体,具有刺激性亚臭味。
- 可燃性危险特性:可燃; 燃烧产生有毒硫氧化物烟雾;患者使用副作用;出血,皮炎,皮肤泛红肿胀
- 方法一:由丙烯醇经加成、巯化而得。
- 储运特性:通风低温干燥; 与库房食品分开存放
- 毒性分级:高毒
- 敏感性:Air Sensitive
- 上游原料:丙烯醇
- 二巯丙醇价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 30065780 2,3-二巯基丙醇(+4℃) 5g 895元 2011/04/16 D0621 2,3-二巯基-1-丙醇 2,3-Dimercapto-1-propanol 25G 3650元 2011/04/16 D0621 2,3-二巯基-1-丙醇 2,3-Dimercapto-1-propanol 1G 356元
- Sigma Aldrich:59-52-9(sigmaaldrich)
- 有类似蒜的特臭。能溶于水,极易溶于甲醇、乙醇和苯甲酸及植物油。水溶液不稳定。1克本品可溶于13毫升水并同时分解,生成二硫化物。有类似的葱蒜样的气味。在空气中易氧化,在乙醇中密封可长期保存。