Desoxycortone 11-去氧皮质酮
CAS 64-85-7 MFCD00003661
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分类
- {SNA} Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Cytokines, Growth Factors and Hormones, H, Hormones, Progesterone, Steroid Hormones
- {SNA} Bioactive Small Molecules, Cell Signaling and Neuroscience, Cytokines, Growth Factors and Hormones, H, Hormones, Progesterone, Steroid Hormones, 细胞生物学
- {SNA} Bioactive Small Molecule Alphabetical Index, Cytokines, Growth Factors and Hormones, H, Hormones, Progesterone, Steroid Hormones, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
- Bioactive Small Molecules,
产品应用
- A mineralocorticoid that occurs in adrenal cortex. It acts as a precursor to Aldosterone (A514700).
相关文献及参考
- Beil. 8 ,IV,2195
- Bohl, C., et al.: J. Med.Chem., 47, 3765 (2004),
- Merck 14 ,2900
- Short: II/27C Title: Diamagnetic Susceptibility and Magnetic Anisotropy of Organic Compounds Author: Kumar, Mahendra; Gupta, Rajni Editor: Gupta, Radha Raman Source: Landolt-Börnstein, New Series Volume: II/27C Year: 2008 Keyword: diamagnetic susceptibility; magnetic anisotropy; organic compounds ISBN: 978-3-540-44734-4 (print) ISBN: 978-3-540-44736-8 (online) Internet Resource: doi:10.1007/978-3-540-44736-8 RefComment: VIII, 204 p., Hardcover RefComment: Written for: Scientists and researchers in the fields of physics, chemistry, materials science RefComment: Supplement and Revised Editon to II/16 Abstract: The volume II/27 has been divided into three subvolumes according to the classes of compounds: Subvolume A: Diamagnetic susceptibility and magnetic anisotropy of inorganic and organometallic compounds; Subvolume B: Diamagnetic susceptibility of organic compounds (Pa
安全信息
GHS Symbol
- P201 Obtain special instructions before use. 使用前获取专门指示。
- P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
- P203
- P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P281 Use personal protective equipment as required. 使用所需的个人防护装备。
- P308+P313
- P314 Get medical advice/attention if you feel unwell. 获取医疗咨询/就医,如果你觉得不舒服
- P318
- P319
- P405 Store locked up. 上锁保管。
- P501 Dispose of contents/container to..… 处理内容物/容器.....
- H351 Suspected of causing cancer 怀疑致癌
- H373 May causes damage to organs through prolonged or repeated exposure 长期或频繁接触可能会损伤器官
- S22 Do not breathe dust 不要吸入粉尘;
- S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
- R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
- R48 Danger of serious damage to health by prolonged exposure 长期接触有严重损害健康的危险
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 7,673,1964
TYPE OF TEST : DNA adduct TEST SYSTEM : Human Liver DOSE/DURATION : 2 mmol/L REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 370,49,1996
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Parenteral SPECIES OBSERVED : Rodent - rat DOSE : 8750 ug/kg SEX/DURATION : female 7 day(s) pre-mating TOXIC EFFECTS : Reproductive - Maternal Effects - uterus, cervix, vagina REFERENCE : JEMEAV Journal of Experimental Medicine. (Rockefeller Univ. Press, 1230 York Ave., New York, NY 10021) V.1- 1896- Volume(issue)/page/year: 102,347,1955
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intramuscular SPECIES OBSERVED : Rodent - rat DOSE : 14500 ug/kg SEX/DURATION : female 7 day(s) pre-mating female 1-22 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Newborn - delayed effects REFERENCE : JCINAO Journal of Clinical Investigation. (Rockefeller Univ. Press, 1230 York Ave., New York, NY 10021) V.1- 1924- Volume(issue)/page/year: 41,710,1962
其他信息
- MSDS 信息:21-Hydroxypregn-4-ene-3,20-dione(64-85-7).msds
- 去氧皮质酮价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2010/06/21 164430025 去氧皮质酮 Desoxycorticosterone 2.5 GR 2455元 2010/06/21 164435000 去氧皮质酮 Desoxycorticosterone 500 MG 624元
- 方法一:用其醋酸酯水解制得该品。
- 比旋光度:184 ° (c=1, C2H5OH)
- 用途一:羟孕酮琥酯钠的合成。
- Acros Organics:去氧皮质酮 Desoxycorticosterone(64-85-7)
- MOL 文件:64-85-7.mol
- Sigma Aldrich:64-85-7(sigmaaldrich)