N-Vinyl-2-Pyrrolidinone 1-乙烯基-2-吡咯烷酮

CAS 88-12-0 MFCD00003197

化学结构图

88-12-0
SMILES: C=CN1CCCC1=O

化学属性

Mol. FormulaC6H9NO
Mol. Weight111.14
Density1.04
Autoignition Point685 °F
Refractive index1.5120 to 1.5150
Vapor Density3.8 (vs air)
Boiling Point217.6°C at 760 mmHg
Vapor Pressure0.1 mmHg ( 24 °C)
Flash Point93.9°C
TSCAYes
Melting Point13-14°C
SolubilityMISCIBLE
Stability对光和热敏感
pH:A

别名和识别编码

Chemical NameN-Vinyl-2-Pyrrolidinone
MDL NumberMFCD00003197
CAS Number88-12-0
EC Number201-800-4
Beilstein Registry Number110513
Synonym 1-Vinylpyrrolidin-2-one {LY} 1-Vinylpyrrolidin-2-one {} {LY} 1-Vinylpyrrolidin-2-one {} {} {LY} 1-Vinylpyrrolidin-2-one {} {} {} {LY} 1-Vinylpyrrolidin-2-one {} {} {} {} {LY} 1-Vinylpyrrolidin-2-one {} {} {} {} {} { {} {} {} {} {} {LY} 1-Vinylpyrrolidin-2-one {} {} {} {} {} {} {LY} 1-Vinylpyrrolidin-2-one {} {} {} {} {} {} {} {LY} 1-Vinylpyrrolidin-2-one {} {} {} {} {} {} {} {} {LY} 1-Vinylpyrrolidin-2-one {} {} {} {} {} {} {} {} {} {LY} 1-Vinylpyrrolidin-2-one {} {} {} {} {} {} {} {} {} {} {LY} 1-Vinylpyrrolidin-2-one {} {} {} {} {} {} {} {} {} {} {} {LY} 1-Vinylpyrrolidin-2-one {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1-Vinylpyrrolidin-2-one {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1-Vinylpyrrolidin-2-one {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1-Vinylpyrrolidin-2-one {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1-Vinylpyrr
PubChem Substance ID6917
Merck Number14,7697
Reaxys-RN110513
Chemical Name Translation1-乙烯基-2-吡咯烷酮
Wiswesser Line NotationT5NVTJ A1U1
LabNetwork Molecule IDLN00196358
InChIInChI=1S/C6H9NO/c1-2-7-5-3-4-6(7)8/h2H,1,3-5H2
Canonical SMILESO=C1N(C=C)CCC1
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分类

  • {SNA} Building Blocks, C4 to C8, Chemical Synthesis, Heterocyclic Building Blocks, Materials Science, Monomers, Polymer Science, Pyrrolidines, Vinyl Halides, Amines, Amides, and Other Vinyl Monomers
  • {SNA} Building Blocks, C4 to C8, Chemical Synthesis, Heterocyclic Building Blocks, Monomers, Polymer Science, Pyrrolidines, Vinyl Halides, Amines, Amides, and Other Vinyl Monomers, 材料科学
  • {SA} Building Blocks, C4 to C8, Chemical Synthesis, Heterocyclic Building Blocks, Pyrrolidines
  • {uni_hamburg} no charge; nitrogen heterocycle; alicycle; 5ring; amide; lactame; 1fragment

相关文献及参考

  • Merck: 14,7697 Beilstein: 21,V,6,330
  • Short: III/35E
  • Short: IV/17
  • Merck: 14,7697

安全信息

Signal word Danger
GHS Symbol
WGK Germany1
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
Risk Statements
  • R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R37 Irritating to respiratory system 刺激呼吸道
  • R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
  • R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
  • R48/20
Precautionary statements
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P312+P330
  • P302+P350
  • P302+P352+P312+P361+P364
  • P304+P340+P312
  • P305+P351+P338
  • P305+P351+P338+P310
  • P308+P313
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
  • P332+P313
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H302+H332
  • H332 Harmful if inhaled 吸入有害
  • H302 Harmful if swallowed 吞食有害
  • H312 Harmful in contact with skin 皮肤接触有害
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H351 Suspected of causing cancer 怀疑致癌
  • H318 Causes serious eye damage 严重伤害眼睛
  • H373 May causes damage to organs through prolonged or repeated exposure 长期或频繁接触可能会损伤器官
  • H302+H312+H332
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
RTECSUY6107000
Packing GroupIII
UN Number 2810 UN2810
Hazard Codes 6.1 Xn
Storage condition 2-8°C {LY} 2-8°C {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C
Hazard Class6.1
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 10 ppm/6H/2Y-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Sense Organs and Special Senses (Olfaction) - tumors
   Liver - tumors
REFERENCE :
   FCTOD7 Food and Chemical Toxicology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.20-    1982- Volume(issue)/page/year:
   35,1041,1997

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3200 mg/m3/4H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BurLW# Personal Communication from L.W. Burnette, Material Safety Dept., GAF
   Corp., 1361 Alps Rd., Wayne, NJ 07470, Nov. 2, 1978 Volume(issue)/page/year:
   02NOV1978

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 560 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BurLW# Personal Communication from L.W. Burnette, Material Safety Dept., GAF
   Corp., 1361 Alps Rd., Wayne, NJ 07470, Nov. 2, 1978 Volume(issue)/page/year:
   02NOV1978

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1470 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BurLW# Personal Communication from L.W. Burnette, Material Safety Dept., GAF
   Corp., 1361 Alps Rd., Wayne, NJ 07470, Nov. 2, 1978 Volume(issue)/page/year:
   02NOV1978

其他信息

  • 用途一:在化妆品、洗涤品、医药、感光材料等诸领域有广泛的应用
  • 常温下是一种无色或淡黄色略有气味的透明液体,易溶于水和其它多种有机溶剂,化学性质活泼易水解和聚合。N-乙烯基吡咯烷酮也是一种性能极其优异的有机溶剂。 爆炸极限expl. lim. 10 %,对光敏感。
  • Sigma Aldrich:88-12-0(sigmaaldrich)
  • 外观性质:常温下是一种无色或淡黄色略有气味的透明液体,易溶于水和其它多种有机溶剂,化学性质活泼易水解和聚合。N-乙烯基吡咯烷酮也是一种性能极其优异的有机溶剂。 爆炸极限expl. lim. 10 %,对光敏感。沸点:92-95℃/11 mmHg闪点:95 °C密度:1.04 折光率n20/D:1.512
  • MOL 文件:88-12-0.mol
  • Alfa Aesar:1-乙烯基-2-吡咯烷酮,99%stab.with0.1%sodiumhydroxide 1-Vinyl-2-pyrrolidinone, 99% stab. with 0.1% sodium hydroxide(88-12-0)
  • 下游产品:5-甲基吲哚 --> 聚乙烯吡咯烷酮
  • 蒸气密度:3.8 (vs air)
  • 图谱信息:N-乙烯基吡咯烷酮(88-12-0)质谱(MS) N-乙烯基吡咯烷酮(88-12-0)核磁图( 1 HNMR) N-乙烯基吡咯烷酮(88-12-0)红外图谱(IR1) N-乙烯基吡咯烷酮(88-12-0)核磁图( 13 CNMR)
  • 蒸气压:0.1 mm Hg ( 24 °C)
  • 上游原料:氢氧化钾 --> 镍 --> 乙二醇 --> 环己烷 --> 丁二酰亚胺
  • N-乙烯基吡咯烷酮价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 AV340902 1-乙烯基-2-吡咯烷酮;乙烯基吡咯烷酮;N-乙烯基-2-吡咯烷酮 250g 534元 2011/08/23 K9506001 N-乙烯基吡咯烷酮 250ml 400元 2011/04/16 V0026 1-乙烯基-2-吡咯烷酮(含稳定剂N,N'-二仲丁基对苯二胺) 1-Vinyl-2-pyrrolidone (stabilized with N,N'-Di-sec-butyl-p-phenylenediamine) 25ML 180元
  • 海关编码:29337900
  • Acros Organics:N-乙烯基-2-吡咯烷酮 N-Vinyl-2-pyrrolidone, stabilized with Kerobit(88-12-0)
  • 检测方法:GC,NMR
  • TCI Shanghai:1-乙烯基-2-吡咯烷酮(含稳定剂N,N'-二仲丁基对苯二胺) 1-Vinyl-2-pyrrolidone (stabilized with N,N'-Di-sec-butyl-p-phenylenediamine),>;99.0%(GC)(88-12-0)
  • MSDS 信息:1-Vinyl-2-pyrrolidone(88-12-0).msds

系列性分类


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