3-Iodo-L-tyrosine 3-碘-L-酪氨酸
CAS 70-78-0 MFCD00002608
化学结构图
SMILES: N[C@@H](Cc1ccc(O)c(I)c1)C(=O)O
化学属性
| Mol. Formula | C9H10INO3 |
|---|---|
| Mol. Weight | 307.09 |
| Density | 1.944 |
| Melting Point | 210°C |
| Stability | 对光敏感 |
| Solubility | dilute aqueous acid: soluble |
| Boiling Point | 391°C at 760 mmHg |
别名和识别编码
| Chemical Name | 3-Iodo-L-tyrosine |
|---|---|
| CAS Number | 70-78-0 |
| Synonym | H-Tyr(3-I)-OH {LY} H-Tyr(3-I)-OH {} {LY} H-Tyr(3-I)-OH {} {} {LY} H-Tyr(3-I)-OH {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {} {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {} {} {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {} {} {} {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {} {} {} {} {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {} {} {} {} {} {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} H- |
| EC Number | 200-744-8 |
| Beilstein Registry Number | 2941266 |
| MDL Number | MFCD00002608 |
| PubChem Substance ID | 439744 |
| Reaxys-RN | 2941266 |
| Merck Number | 5047 |
| Chemical Name Translation | 3-碘-L-酪氨酸 |
| LabNetwork Molecule ID | LN00194297 |
| InChI | InChI=1S/C9H10INO3/c10-6-3-5(1-2-8(6)12)4-7(11)9(13)14/h1-3,7,12H,4,11H2,(H,13,14)/t7-/m0/s1 |
| Canonical SMILES | O=C(O)[C@@H](N)CC1=CC=C(O)C(I)=C1 |
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专业采购外包团队在线服务
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分类
- {SNA} Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Enzyme Inhibitors, I, Neuroscience, Neurotransmission, Neurotransmitter Metabolism, Tyrosine Hydroxylase
- Inhibitors
- Amino Acids & Derivatives
- Chiral Reagents
- {SNA} Enzyme Inhibitors, Neuroscience, Neurotransmission, Neurotransmitter Metabolism, Tyrosine Hydroxylase, 细胞信号转导和神经科学, 细胞生物学
- {SNA} Bioactive Small Molecules, Cell Signaling and Neuroscience, Enzyme Inhibitors, I, Neuroscience, Neurotransmission, Neurotransmitter Metabolism, Tyrosine Hydroxylase,
产品应用
- 酪氨酸羟化酶抑制剂。
相关文献及参考
- [2]. D K Ness, et al. Effects of 3-iodo-L-tyrosine, a tyrosine hydroxylase inhibitor, on eye pigmentation and biogenic amines in the planarian, Dugesia dorotocephala. Fundam Appl Toxicol. 1996 Apr;30(2):153-61.
- Fitzpatrick, P.F., Steady-state kinetic mechanism of rat tyrosine hydroxylase. Biochemistry 30 , 3658-3662, (1991) 摘要
- Fitzpatrick, P.F., et al.: Biochemistry, 30, 3658 (1991),
- Harsing, L.G., et al.: Neuroscience, 77, 419 (1997),
- Merck 14 ,5047
- Merck: 14,5047 Beilstein: 14,IV,2369
- [1]. GOLDSTEIN M, et al. INHIBITION OF TYROSINE HYDROXYLASE BY 3-IODO-L-TYROSINE. Life Sci (1962). 1965 Jan;4:261-4.
- [1]. GOLDSTEIN M, et al. INHIBITION OF TYROSINE HYDROXYLASE BY 3-IODO-L-TYROSINE. Life Sci (1962). 1965 Jan;4:261-4.
- [2]. D K Ness, et al. Effects of 3-iodo-L-tyrosine, a tyrosine hydroxylase inhibitor, on eye pigmentation and biogenic amines in the planarian, Dugesia dorotocephala. Fundam Appl Toxicol. 1996 Apr;3
安全信息
GHS Symbol
- S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。
其他信息
- Acros Organics:3-碘-L-酪氨酸 3-Iodo-L-tyrosine, 97%(70-78-0)
- TCI Shanghai:3-碘-L-酪氨酸 3-Iodo-L-tyrosine,>;99.0%(T)(70-78-0)
- 3-碘-L-酪氨酸价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/04/16 I0075 3-碘-L-酪氨酸 3-Iodo-L-tyrosine 1G 515元 2011/04/16 I0075 3-碘-L-酪氨酸 3-Iodo-L-tyrosine 5G 1680元 2010/06/21 122440010 3-碘-L-酪氨酸 3-Iodo-L-tyrosine 97% 1 GR 470元
- 3-碘-L-酪氨酸价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 I0075 3-碘-L-酪氨酸 3-Iodo-L-tyrosine 1G 488元 2014/06/02 I0075 3-碘-L-酪氨酸 3-Iodo-L-tyrosine 5G 1600元 2010/06/21 122440010 3-碘-L-酪氨酸 3-Iodo-L-tyrosine 97% 1 GR 470元
- MOL 文件:70-78-0.mol
- Sigma Aldrich:70-78-0(sigmaaldrich)
- F:8-10-23
- 溶于15份沸水。
