CAS 54-21-7 MFCD00002440-Sodium salicylate 水杨酸钠 TAO{mole}

Sodium salicylate 水杨酸钠

CAS 54-21-7 MFCD00002440

化学结构图

SMILES: [Na+].[O-]C(=O)C1C=CC=CC=1O

化学属性

Mol. Formula	C7H5NaO3
Mol. Weight	160.10
Density	1.015
Melting Point	>300 °C
TSCA	Yes
Solubility	Soluble in water (1000 g/l) at 20 °C, ethanol, and glycerol.
Stability	对光敏感

别名和识别编码

Chemical Name	Sodium salicylate
Synonym	Sodium Salicylate {LY} Sodium Salicylate {} {LY} Sodium Salicylate {} {} {LY} Sodium Salicylate {} {} {} {LY} Sodium Salicylate {} {} {} {} {} {} {} {} {LY} Sodium Salicylate {} {} {} {} {} {LY} Sodium Salicylate {} {} {} {} {} {} {LY} Sodium Salicylate {} {} {} {} {} {} {} {LY} Sodium Salicylate {} {} {} {} {} {} {} {} {LY} Sodium Salicylate {} {} {} {} {} {} {} {} {} {LY} Sodium Salicylate {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Sodium Salicylate {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Sodium Salicylate {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Sodium Salicylate {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Sodium Salicylate {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Sodium Salicylate {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Sodium Salicylate {} {} {} {} {} {} {} {} {}
CAS Number	54-21-7
EC Number	200-198-0
Beilstein Registry Number	3732792
MDL Number	MFCD00002440
PubChem Substance ID	24899533
Merck Number	14,8332
Chemical Name Translation	水杨酸钠
Wiswesser Line Notation	QVR BQ &-NA-
LabNetwork Molecule ID	LN03240012
Canonical SMILES	O=C(O[Na])C1=CC=CC=C1O

信息真实价格透明资金保障专业采购外包团队在线服务

品牌质保精细包装现货库存一流品牌服务

产品应用

有机合成原料；防腐剂；测胃液中游离酸的试剂；点滴分析二氧化铀。解热镇痛药和抗风湿药。

安全信息

Signal word Warning

GHS Symbol

WGK Germany1

Safety Statements

S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护；

Risk Statements

R22 Harmful if swallowed 吞咽有害
R36 Irritating to eyes 刺激眼睛
R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
R41 Risk of serious damage to eyes 有严重损伤眼睛的危险

Precautionary statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P301+P312
P302+P352
P305+P351+P338

Hazard statements

H315 Causes skin irritation 会刺激皮肤
H335 May cause respiratory irritation 可能导致呼吸道刺激
H302 Harmful if swallowed 吞食有害
H319 Causes serious eye irritation 严重刺激眼睛

Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves

RTECSVO5075000

Storage condition Store at room temperature, keep dry and cool {LY} Store at room temperature, keep dry and cool {} {LY} Store at room temperature, keep dry and cool {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {} {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature, keep

Hazard Codes Xn

TYPE OF TEST            : LDL

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 540 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 5,572,1955

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Human - woman
DOSE/DURATION           : 1400 mg/kg
TOXIC EFFECTS :
   Behavioral - toxic psychosis
   Lungs, Thorax, or Respiration - respiratory stimulation
   Skin and Appendages - sweating
REFERENCE :
   JAMAAP JAMA, Journal of the American Medical Association.  (AMA, 535 N.
   Dearborn St., Chicago, IL 60610)  V.1-    1883-  Volume(issue)/page/year:
   126,806,1944

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 760 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   APSVAM Acta Paediatrica Scandinavica.  (Almqvist & Wiksell International,
   POB 4627, S-11691 Stockholm, Sweden)  V.54-80    1965-91    For publisher
   information, see APAEEL  Volume(issue)/page/year: 59,517,1970

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Amphibian - frog
DOSE/DURATION           : 250 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig,
   Ger. Dem. Rep.)  Volume(issue)/page/year: 4,1392,1935

{hazard_co

TYPE OF TEST            : Cytogenetic analysis
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 370,1,1996

TYPE OF TEST            : DNA damage
TEST SYSTEM             : Rodent - rat Liver
DOSE/DURATION           : 240 mg/L
REFERENCE :
   BIORAK Biochemistry (English Translation).  Translation of BIOHAO.  (Plenum
   Pub. Corp., 233 Spring St., New York, NY 10013)  V.21-    1956-
   Volume(issue)/page/year: 34,934,1969

TYPE OF TEST            : DNA damage
TEST SYSTEM             : Rodent - rat Embryo
DOSE/DURATION           : 30 mg/L
REFERENCE :
   BIORAK Biochemistry (English Translation).  Translation of BIOHAO.  (Plenum
   Pub. Corp., 233 Spring St., New York, NY 10013)  V.21-    1956-
   Volume(issue)/page/year: 34,934,1969

TYPE OF TEST            : DNA damage
ROUTE OF EXPOSURE       : Unreported
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 600 mg/kg
REFERENCE :
   BIOHAO Biokhimiya (Moscow).  For English translation, see BIORAK.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 34,1151,1969

TYPE OF TEST            : Cytogenetic analysis
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 350 mg/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 370,1,1996

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 600 mg/kg
SEX/DURATION            : female 6-13 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
REFERENCE :
   TJADAB Teratology, The International Journal of Abnormal Development. (Alan
   R. Liss, Inc., 41 E. 11th St., New York, NY 10003)  V.1-    1968-
   Volume(issue)/page/year: 33,43A,1986

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        :

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 400 mg/kg
SEX/DURATION            : female 10 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
   Reproductive - Specific Developmental Abnormalities - other developmental
   abnormalities
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 41(12),32,1976

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 500 mg/kg
SEX/DURATION            : female 17 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Maternal Effects - parturition
REFERENCE :
   NATUAS Nature.  (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736)
   V.1-    1869-  Volume(issue)/page/year: 220,385,1968

其他信息

下游产品:水杨酸 --> 柳酸苄酯 --> 3,6-二氯-2-羟基苯甲酸 --> 媒介黄 1
Acros Organics:水杨酸钠 Salicylic acid, sodium salt, 99+%(54-21-7)
易溶于水（1：0.8，25℃）和甘油（1：5），能溶于95%乙醇（1：11），几乎不溶于醚、氯仿和苯。水溶液呈微酸性（pH5-6）。久露光线中变粉红色。无臭或微带特殊的臭气，味甜呀不适。
图谱信息:水杨酸钠(54-21-7)红外图谱(IR1) 水杨酸钠(54-21-7)红外图谱(IR2) 水杨酸钠(54-21-7)Raman光谱
F:8
用途三:有机合成原料、防腐剂、测胃液中游离酸的试剂。解热镇痛药和抗风湿药。
Alfa Aesar:水杨酸钠,99% Sodium salicylate, 99%(54-21-7)
MOL 文件:54-21-7.mol
用途一:解热镇痛、抗风湿药，用于活动性风湿病、类风湿关节炎等疾病的治疗
MSDS 信息:水杨酸钠(54-21-7).msds
上游原料:连二亚硫酸钠 --> 水杨酸 --> 乙二胺四乙酸
水杨酸钠价格(试剂级):更新日期产品编号产品名称包装价格 2011/08/23 30169317 水杨酸钠 250g 27元 2011/08/23 30169327 水杨酸钠 250g 26元 2011/08/23 HW6610901 水杨酸钠 250g 475元
海关编码:29182100
用途二:用于微量分析测定二氧化铀及有机合成，还用作防腐剂等
方法一:将水杨酸和碳酸氢钠交叉加入蒸馏水中，温度保持60℃，并保持呈酸性状态，同时加入适量乙二胺四乙酸（EDTA）及保险粉。升温至85℃，反应半小时。将合格的反应液经过滤送入沸腾床，85℃干燥得水杨酸。
Sigma Aldrich:54-21-7(sigmaaldrich)
用途四:有机合成原料；防腐剂；测胃液中游离酸的试剂；点滴分析二氧化铀。解热镇痛药和抗风湿药。
外观性质:白色鳞片或粉末，无气味，久露光线中变粉红色。
敏感性:Light Sensitive