CAS 1948-33-0 MFCD00002344-tert-Butylhydroquinone 叔丁基对苯二酚 TAO{mole}

tert-Butylhydroquinone 叔丁基对苯二酚

CAS 1948-33-0 MFCD00002344

化学结构图

SMILES: CC(C)(C)c1cc(O)ccc1O

化学属性

Mol. Formula	C10H14O2
Mol. Weight	166
Density	1.241
Autoignition Point	855 °F
Melting Point	127.0 to 131.0 deg-C
Flash Point	171°(339°F)
TSCA	Yes
Boiling Point	295
Stability	对湿度敏感
Appearance	白色至淡灰色结晶或结晶性粉末。有极轻微的特殊气味。溶于乙醇、乙酸、乙酯、异丙醇、乙醚及植物油、猪油等，几不溶于水(25℃，<;1%；95℃，5%)。沸点300℃，熔点126.5～128.5℃。对大多数油脂均有防止胯败作用，尤其是植物油。遇铁、铜不变色，但如有碱存在可转为粉红色。

别名和识别编码

Chemical Name	tert-Butylhydroquinone
CAS Number	1948-33-0
EC Number	217-752-2
Beilstein Registry Number	637923
MDL Number	MFCD00002344
PubChem Substance ID	87563817
Synonym	tert-Butylhydroquinone 2-特丁基对苯二酚 tert-Butyl-1,4-benzenediol 叔丁基对苯二酚（TBHQ） 4-Benzenediol,2-(1,1-dimethylethyl)-1 T-BUTYLHYDROQUINONE 特丁基对苯二酚 TERT-BUTYLHYDROQUINONE 抗氧剂TBHQ 264-氢醌 T-丁基氢醌 TBHQ T-丁基-1 叔丁基对苯二酚/2-叔丁基氢醌/TBHQ Butylhydroquinone; TBHQ; 2-tert-Butylhydroquinone; 2-(1,1-Dimethylethyl)-1,4-benzenediol 2-叔丁基氢醌 2-T-BUTYLHYDROQUINONE 叔丁基对苯二酚 2-(1,1-Dimethylethyl)-1,4-benzenediol 2-三級丁二氫醌 2-特丁基对苯二酚 Butylhydroquinone TERTIARY BUTYL HYDROQUINONE TERT-BUTYLHYDROCHINONE 叔丁基氢醌 2-TERT-BUTYL-1,4-BENZENEDIOL 2-(1,1-Dimethylethyl)-1,4-benzenediol NSC 4972 1-dimethylethyl)-4-benzenediol(1 2-TERT-BUTYL-1,4-DIHYDROXYBENZENE 1-T-BUTYL-1,4-DIHYDROXYBENZENE 邻叔丁基对苯二酚 T-丁基-1,4-苯酚 2-tert-butylhydroquinen 1,4-Benzenediol, 2-(1,1-dimethylethyl)- 2-tetrabutyl-1,4-dihydroxybenzene MONO-TERT-BUTYLHYDROQUINONE 4-苯酚 2-(1,1-dimethylethyl)-4-benzenediol TBHQ T-丁基-1,4-苯酚,特丁基对苯二酚,叔丁基氢醌,2-特丁基对苯二酚 Tenox TBHQ 2-t-Butyl-1,4-benzenediol TBHQ 2-tert-butylhydroquinone 特丁基对苯三酚 banox20ba Sustane 第三丁基对苯二酚
Reaxys-RN	637923
Chemical Name Translation	叔丁基对苯二酚
Wiswesser Line Notation	QR DQ BX1&1&1
LabNetwork Molecule ID	LN00193421
InChI	InChI=1S/C10H14O2/c1-10(2,3)8-6-7(11)4-5-9(8)12/h4-6,11-12H,1-3H3

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产品应用

对大多数油脂、塑料、橡胶等均有防止氧化作用。遇铁、铜不变色，但如有碱存在可转为粉红色。抗氧化性能优越。

安全信息

Signal word

GHS Symbol

WGK Germany3

Safety Statements

Risk Statements

R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

Precautionary statements

P302+P352+P332+P313+P362+P364
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P501 Dispose of contents/container to..… 处理内容物/容器.....
P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P305+P351+P338
P332+P313
P273 Avoid release to the environment. 避免释放到环境中。
P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
P305+P351+P338+P337+P313
P301+P312+P330
P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
P302+P350
P337+P313

Hazard statements

H315 Causes skin irritation 会刺激皮肤
H335 May cause respiratory irritation 可能导致呼吸道刺激
H302 Harmful if swallowed 吞食有害
H319 Causes serious eye irritation 严重刺激眼睛

Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves

RTECSMX4375000

Packing GroupIII

UN Number UN3077 3077

Hazard Codes

Storage condition 密封保存。

Hazard Class9

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 700 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JAOCA7 Journal of the American Oil Chemists' Society.  (Champaign, IL)
   V.24-56, 1947-79.  Volume(issue)/page/year: 52,53,1975

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JAOCA7 Journal of the American Oil Chemists' Society.  (Champaign, IL)
   V.24-56, 1947-79.  Volume(issue)/page/year: 52,53,1975

TYPE OF TEST            : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2900 mg/m3/4H
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - effect, not otherwise specified
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology,
   Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128)  V.1-
   1990-  Volume(issue)/page/year: 1,753,1992

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 790 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   WHFAAC WHO Food Additives Series.  (Geneva, Switzerland)  No.1-8, 1972-75.
   Discontinued.  Volume(issue)/page/year: 8,26,1975

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 20 mg/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 241,125,1990

TYPE OF TEST            : Mutation in mammalian somatic cells
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 1700 ug/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 280,17,1992

TYPE OF TEST            : Sister chromatid exchange
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 20 mg/kg
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   13,234,1989

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 170 ug/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amst

TYPE OF TEST            : Unscheduled DNA synthesis
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 33600 mg/kg/4W (Continuous)
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   99,37,1989

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 170 ug/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 280,17,1992

TYPE OF TEST

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 32500 mg/kg
SEX/DURATION            : female 13 week(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Maternal Effects - other effects
   Reproductive - Effects on Newborn - viability index (e.g., # alive at day 4
   per # born alive)
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-459,1997

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 39 gm/kg
SEX/DURATION            : male 13 week(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - mating performance (e.g. # sperm positive females
   per # females mated; # copulations per # estrus cycles)
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-459,1997

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 39 gm/kg
SEX/DURATION            : male 13 week(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - testes, epididymis, sperm duct
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-459,1997

其他信息

可燃性危险特性:热分解排出有毒辛辣刺激烟雾
毒性分级:中毒
急性毒性:口服-大鼠 LD50: 700 毫克/公斤; 口服-小鼠 LD50: 1000 毫克/公斤
TCI Shanghai:叔丁基-1,4-苯酚 tert-Butylhydroquinone,>;98.0%(GC)(1948-33-0)
叔丁基氢醌价格(试剂级):更新日期产品编号产品名称包装价格 2011/08/23 xw010226 叔丁基对苯二酚;叔丁基氢醌 100g 80元 2011/08/23 TB083302 叔丁基对苯二酚;叔丁基氢醌 25g 149元 2011/04/16 B0833 叔丁基对苯二酚 tert-Butylhydroquinone 25G 139元
Sigma Aldrich:1948-33-0(sigmaaldrich)
储运特性:库房通风低温干燥
用途二:抗氧化剂。适用于粗油和高度不饱和油脂，如向日葵油等。对烹调用油和焙烤制品，宜与BHA合用，但适用于煮炸制品。一般用量100～200mg/kg。
Alfa Aesar:叔丁基对苯二酚,97% tert-Butylhydroquinone, 97%(1948-33-0)
MSDS 信息:Butylhydroquinone(1948-33-0).msds
用途三:作抗氧化剂，可用于食用油脂、油炸食品、饼干、方便面、速煮米、干果罐头、干鱼制品和腌制肉制品，最大使用量为0.2g/kg。
图谱信息:叔丁基氢醌(1948-33-0)红外图谱(IR1) 叔丁基氢醌(1948-33-0)红外图谱(IR2) 叔丁基氢醌(1948-33-0)质谱(MS)
食品添加剂最大允许使用量最大允许残留量标准:添加剂中文名称允许使用该种添加剂的食品中文名称添加剂功能最大允许使用量（g/kg）最大允许残留量（g/kg）特丁基对苯二酚烘炒坚果食品抗氧化剂 0.2 特丁基对苯二酚油炸食品抗氧化剂 0.2 特丁基对苯二酚风干、烘干、压干等水产品抗氧化剂 0.2 特丁基对苯二酚腌腊肉制品类（如咸肉、腊肉、板鸭、中式火腿、腊肠等）抗氧化剂 0.2 特丁基对苯二酚饼干抗氧化剂 0.2 特丁基对苯二酚方便米面制品抗氧化剂
类别:有毒物质
上游原料:1,4-苯二酚 --> 异丁烯 -->
用途四:对大多数油脂、塑料、橡胶等均有防止氧化作用。遇铁、铜不变色，但如有碱存在可转为粉红色。抗氧化性能优越。
参考质量标准:QB 2395-1998 特丁基对苯二酚含量(以C10H14O2计)/% ≥99.0 特丁基对苯醌/% ≤0.2 2，5-二叔丁基氢醌/% ≤0.2 氢醌/% ≤0.1 甲苯/% ≤0.0025 砷(以As计)/% ≤0.0003 重金属(以Pb计)/% ≤0.001 熔点/℃ 126.5～128.5
用途一:用作PVC抗鱼眼剂及食品添加剂
方法一:由2，6一二叔丁基苯与KOH在乙醇中反应后加人2一糠酰啶，进行回流反应后静置析出初品，再用乙醇洗涤并重结晶而得(IISP4222883，Sep 16，1980)。
Acros Organics:叔丁基对苯二酚 tert-Butylhydroquinone, 97%(1948-33-0)
叔丁基对苯二酚有一种极淡的特殊香味，几乎不溶于水（约为 5‰ ），溶于乙醇、乙酸、乙酯、乙醚及植物油等。
方法二:磷酸催化法在甲苯、对苯二酚和60%磷酸的混合物中加入异丁烯或叔丁醇，在105℃下反应生成TBHQ，产率为89%。硫酸催化法在浓硫酸或磺酸存在下，对苯二酚与叔丁醇于90℃下反应生成41.0%(mo1)的TBHQ和5.1%(mo1)的2，5-二特丁基对苯二酚。
下游产品:叔丁基-4-羟基苯甲醚
灭火剂:水, 干粉, 二氧化碳, 泡沫
MOL 文件:1948-33-0.mol