3-(Dimethylamino)propionitrile 3-(二甲基氨基)丙腈
CAS 1738-25-6 MFCD00001957
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分类
- {Chemicalbook} 农药中间体: 杀菌剂中间体: 氨基甲酸酯类杀菌剂
- {uni_hamburg} no charge; 1fragment
- {SNA} Building Blocks, C1 to C5, Chemical Synthesis, Cyanides/Nitriles, Nitrogen Compounds, Organic Building Blocks
- {SNA} Building Blocks, C1 to C5, Chemical Synthesis, Cyanides/Nitriles, Nitrogen Compounds, Organic Building Blocks, Protein Sequencing, Protein Structural Analysis, Proteomics, Reagents for Protein Sequencing
相关文献及参考
- Short: IV/20C Title: Vapor Pressure and Antoine Coefficients for Nitrogen Containing Organic Compounds Author: Dykyj, J.; Svoboda, J.; Wilhoit, R.C.; Frenkel, M.; Hall, K.R. Editor: Hall, K.R. Source: Landolt-Börnstein, New Series Volume: IV/20C Year: 2001 Keyword: organic compounds; vapor pressure ISBN: 3-540-41060-0 ISBN: 978-3-540-41060-7 Internet Resource: DOI:10.1007/b88812 RefComment: VII, 197 pages
- Short: IV/8A Title: Enthalpies of Fusion and Transition of Organic Compounds Author: Zhang, Z.-Y.; Frenkel, M.; March, K.N.; Wilhoit, R.C. Editor: Marsh, K.N. Source: Landolt-Börnstein, New Series Volume: IV/8A Year: 1995 Keyword: organic compounds; enthaly of fusion; melting point; phase transition ISBN: 3-540-58854-X ISBN: 978-3-540-58854-2 Internet Resource: DOI:10.1007/b55145 RefComment: VIII, 588 pages.
- Short: EINECS Title: EINECS (European Inventory of Existing Commercial Chemical Substances) Source: Official Journal of the European Communities Volume: C 146 A (15.06.1990) Page: 1 Year: 1990 Internet Resource: http://ecb.jrc.ec.europa.eu/esis/index.php?PGM=ein Publish_Date: 1990/06/15
安全信息
GHS Symbol
- R21 Harmful in contact with skin 与皮肤接触有害
- R36 Irritating to eyes 刺激眼睛
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- R36/38 Irritating to eyes and skin 对眼睛和皮肤有刺激性
- R22 Harmful if swallowed 吞咽有害
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P501 Dispose of contents/container to..… 处理内容物/容器.....
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P305+P351+P338
- P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
- P332+P313
- P305+P351+P338+P337+P313
- P302+P350
- P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
- P337+P313
- P302+P352+P312+P362+P364
- H227 Combustible liquid 可燃液体
- H302+H312
- H319 Causes serious eye irritation 严重刺激眼睛
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 2600 uL/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 1410 uL/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 180 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#00201
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,923,1986
其他信息
- 毒性分级:中毒
- 方法一:其制备方法是在反应釜中投入丙烯腈,开动搅拌和夹套水,在适宜的温度下通入二甲胺气体至规定量,反应1h取样分析得产品。反应方程式:CH 2 =CHCN+(CH 3 ) 2 NH→(CH 3 ) 2 NCH 2 CH 2 CN
- Acros Organics:3-(二甲基氨基)丙腈 3-(Dimethylamino)propionitrile, 99%(1738-25-6)
- MSDS 信息:β-二甲氨基丙腈(1738-25-6).msds
- 刺激数据:皮肤-兔子 500 毫克/24小时 轻度; 眼睛-兔子 20 毫克/24小时 中度
- 类别:有毒物品
- 图谱信息:二甲氨基丙腈(1738-25-6)质谱(MS) 二甲氨基丙腈(1738-25-6)核磁图( 13 CNMR) 二甲氨基丙腈(1738-25-6)核磁图( 1 HNMR) 二甲氨基丙腈(1738-25-6)红外图谱(IR1)
- 用途一:用于固氮酶细胞分析中蛋白质、酶、核酸分子量的圆盘电泳法的测定
- 海关编码:29269095
- MOL 文件:1738-25-6.mol
- 可燃性危险特性:明火可燃; 受热放出剧毒含腈气体
- Sigma Aldrich:1738-25-6(sigmaaldrich)
- 外观性质:无色透明液体,久置空气中易变质。
- 用途二:β-二甲氨基丙腈是杀菌剂霜霉威的中间体。
- 上游原料:二甲胺 --> 丙烯腈
- 二甲氨基丙腈价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 80051026 3-二甲氨基丙腈;2-二甲氨基乙基氰; β-二甲氨基丙腈 100ml 38元 2011/04/16 D0662 3-二甲基氨基丙腈 3-Dimethylaminopropionitrile 500ML 2150元 2011/04/16 D0662 3-二甲基氨基丙腈 3-Dimethylaminopropionitrile 25ML 211元
- 灭火剂:雾状水、泡沫、干粉、二氧化碳、砂土
- 下游产品:霜霉威 --> N,N-二甲基-1,3-二氨基丙烷
- 用途三:有机合成中间体,用于合成多种维生素B,也可用作有机溶剂、高分子合成引发剂(促聚剂)以及电镀添加剂的中间体。作为分析试剂,用于固氮酶细胞的分析中蛋白质、酶、核梅分子量的圆盘电泳法的测定。
- 储运特性:库房通风低温干燥; 与食品、氧化剂、酸类分开储运
- 职业标准:STEL 10 毫克/立方米
- 急性毒性:口服-大鼠 LD50: 2600 毫克/ 公斤; 口服-小鼠 LD50: 1500 毫克/ 公斤
- 方法二:由丙烯腈与二甲胺反应而得。先将丙烯腈在冰冷却下加入二甲胺溶液中,然后进行加热,通过吸收,分馏精馏,收集171-173℃馏分,即得本品。原料消耗定额:丙烯腈670kg/t、二甲胺(40%)1500kg/t。
- TCI Shanghai:3-(二甲基氨基)丙腈 3-Dimethylaminopropionitrile,>;98.0%(GC)(1738-25-6)
- F:8