2-Chloroacrylonitrile 2-氯丙烯腈
CAS 920-37-6 MFCD00001858
信息真实价格透明
资金保障
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信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- Building Blocks, C1 to C5, Chemical Synthesis, Cyanides/Nitriles, Nitrogen Compounds, Organic Building Blocks
- {Chemicalbook} 农药中间体: 杀虫剂中间体: 其他杀虫剂
- {uni_hamburg} no charge; 1fragment
- {SNA} Building Blocks, C1 to C5, Chemical Synthesis, Cyanides/Nitriles, Nitrogen Compounds, Organic Building Blocks
产品应用
- 环加成反应(cycloaddition reactions)的常用试剂。
相关文献及参考
- Beilstein: 2,IV,1484
- Short: II/24B
- Short: II/14a
安全信息
GHS Symbol
- H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
- H300 Fatal if swallowed 吞食致命
- H301 Toxic if swallowed 吞食有毒
- H310 Fatal in contact with skin 皮肤接触致命
- H311 Toxic in contact with skin 皮肤接触中毒
- H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
- H330 Fatal if inhaled 吸入致命
- H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled 吸入可能导致过敏或哮喘症状或呼吸困难
- H350 May cause cancer 可能致癌
- H400 Verytoxictoaquaticlife 对水生生物毒性非常大。
- P201 Obtain special instructions before use. 使用前获取专门指示。
- P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
- P203
- P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
- P211 Do not spray on an open flame or other ignition source.? 不要喷洒在明火或其他点火源。
- P233 Keep container tightly closed. ?保持容器密闭。
- P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
- P241 Use explosion-proof electrical/ventilating/lighting/…/equipment. 使用防爆电气/通风/照明/ .../设备。
- P241+P242+P243
- P242 Use only non-sparking tools. 只能使用无火花工具。
- P243 Take precautionary measures against static discharge. 采取预防措施,防止静电放电。
- P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛,皮肤或衣服。
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
- P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
- P273 Avoid release to the environment. 避免释放到环境中。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P281 Use personal protective equipment as required. 使用所需的个人防护装备。
- P284 Wear respiratory protection.? 佩戴呼吸保护装置。
- P285 In case of inadequate ventilation wear respiratory protection. 在通风不足的情况下,戴呼吸防护。
- P301+P310
- P301+P310+P330
- P301+P316
- P301+P330+P331
- P302+P350
- P302+P352
- P302+P352+P333+P313+P362+P364
- P302+P361+P354
- P303+P361+P353
- P304+P340
- P304+P341
- P305+P351+P338
- P305+P351+P338+P337+P313
- P305+P354+P338
- P308+P313
- P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
- P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
- P314 Get medical advice/attention if you feel unwell. 获取医疗咨询/就医,如果你觉得不舒服
- P316
- P318
- P320 Specific treatment is urgent (see … on this label). 紧急具体治疗(见本标签上的)。
- P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
- P322 Specific measures (see …on this label). 具体治疗(见本标签上的)。
- P330 Rinse mouth. 漱口
- P337+P313
- P342+P311
- P342+P316
- P361 Remove/Take off immediately all contaminated clothing. 立即去除/脱掉所有被污染的衣服。
- P361+P364
- P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
- P370+P378
- P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
- P403 Store in a well-ventilated place. 储存在通风良好的地方。
- P403+P233
- S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
- S53 Avoid exposure - obtain special instructions before use 避免接触,使用前获得特别指示说明;
- S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
- R11 Highly flammable 非常易燃
- R23/24 Toxic by inhalation and in contact with skin 吸入及皮肤接触都有毒
- R24 Toxic in contact with skin 与皮肤接触有毒
- R26/28 Very toxic by inhalation and if swallowed 吸入及吞食都有剧毒
- R28 Very toxic if swallowed 吞咽极毒
- R34 Causes burns 会导致灼伤
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
- R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
- R45 May cause cancer 可能致癌
- R50 Very toxic to aquatic organisms 对水生生物极毒
TYPE OF TEST : LCLo - Lowest published lethal concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 304 mg/m3/6H TOXIC EFFECTS : Vascular - regional or general arteriolar or venous dilation Lungs, Thorax, or Respiration - dyspnea Skin and Appendages - hair REFERENCE : NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0555346
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 10 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Vascular - regional or general arteriolar or venous dilation Lungs, Thorax, or Respiration - dyspnea REFERENCE : NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0555346
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 100 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#02164
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 25 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - ataxia Skin and Append
TYPE OF TEST : LD50 - Lethal dose, 50
其他信息
- 毒性分级:剧毒
- MSDS 信息:1-氯丙烯腈(920-37-6).msds
- 方法一:其制备方法是在装有搅拌、温度计和冷凝管的四口烧瓶中,加入丙烯腈和氯化催化剂,在冰水浴冷却和搅拌条件下,向反应液中通氯气,反应体系控制在30~35℃,通氯气约需4h,用GC跟踪氯化终点,继续搅拌1h,得到的反应液即为二氯丙腈。将上述反应液加入具搅拌温度计和瓷环填料柱的烧瓶中,加入少许阻聚剂,搅拌并加热,温度105~110℃,开始回流,控制釜温110~130℃,同时进行消除反应并分馏,塔顶温度85℃,收集馏分即为成品。
- 灭火剂:二氧化碳, 泡沫, 干粉
- 下游产品:萎蔫酸 --> 5-丁基吡啶-2-甲腈 --> 4-氯噻吩并[3,2-d]嘧啶 --> 3-氯噻吩-2-羧酸甲酯
- 上游原料:阻聚剂 --> 四口烧瓶 --> 瓷环填料
- 可燃性危险特性:遇热, 明火, 氧化剂燃烧; 热分解排出有毒氮氧化物, 氰化物, 氯化物烟雾
- Hazard Note:Flammable/Very Toxic
- 2-氯丙烯腈价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 C0701 2-氯丙烯腈(含稳定剂HQ) 2-Chloroacrylonitrile (stabilized with HQ) 500ML 7810元 2014/06/02 C0701 2-氯丙烯腈(含稳定剂HQ) 2-Chloroacrylonitrile (stabilized with HQ) 25ML 942元 2010/06/21 108560050 2-氯丙烯腈 2-Chloroacrylonitrile 99%, stabilized 5 GR 581元
- 类别:易燃液体
- 储运特性:库房低温通风干燥; 防高温, 防明火, 与氧化剂, 食品原料分开存放
- 急性毒性:口服-大鼠 LD50: 25 毫克/公斤; 口服-小鼠 LD50: 25 毫克/公斤
- Acros Organics:2-氯丙烯腈 2-Chloroacrylonitrile, stabilized, 99%(920-37-6)
- Sigma Aldrich:920-37-6(sigmaaldrich)
- 外观性质:液体。
- TCI Shanghai:2-氯丙烯腈(含稳定剂氢醌) 2-Chloroacrylonitrile (stabilized with HQ),>;99.0%(GC)(920-37-6)
- 检测方法:GC,NMR
- 图谱信息:2-氯丙烯腈(920-37-6)质谱(MS) 2-氯丙烯腈(920-37-6)核磁图( 13 CNMR) 2-氯丙烯腈(920-37-6)核磁图( 1 HNMR) 2-氯丙烯腈(920-37-6)红外图谱(IR2) 2-氯丙烯腈(920-37-6)红外图谱(IR1)
- MOL 文件:920-37-6.mol
- 用途二:2-氯丙烯腈是重要的医药和农药中间体,是杀虫剂虫螨腈的中间体,也是除草剂噻吩磺隆的中间体。
- 用途一:用作农药、医药中间体