CAS 2687-12-9 MFCD00000986-Cinnamyl chloride 肉桂基氯 TAO{mole}

Cinnamyl chloride 肉桂基氯

CAS 2687-12-9 MFCD00000986

化学结构图

SMILES: ClCC=Cc1ccccc1

化学属性

Mol. Formula	C9H9Cl
Mol. Weight	152.62
Density	1.096
Refractive index	1.5820 to 1.5850
Flash Point	96.6°C
TSCA	Yes
Boiling Point	239.6°C at 760 mmHg
Melting Point	7°C
Solubility	200 MG/L (20 ºC)
Appearance	针状结晶或无色液体。熔点8-9℃，沸点125-126℃（2.93kPa），106.7℃（1.73kPa），55-56℃（93Pa），相对密度1.0926，折光率1.5851，闪点79℃。能与醇、醚任意混溶，易溶于丙酮，能溶于苯，不溶于水。
Stability	对湿度敏感

别名和识别编码

Chemical Name	Cinnamyl chloride
Synonym	(3-Chloroprop-1-en-1-yl)benzene {LY} (3-Chloroprop-1-en-1-yl)benzene {} {LY} (3-Chloroprop-1-en-1-yl)benzene {} {} {LY} (3-Chloroprop-1-en-1-yl)benzene {} {} {} {LY} (3-Chloroprop-1-en-1-yl)benzene {} {} {} {} {LY} (3-Chloroprop-1-en-1-yl)benzene {} {} {} {} {} {LY} (3-Chloroprop-1-en-1-yl)benzene {} {} {} {} {} {} {LY} (3-Chloroprop-1-en-1-yl)benzene {} {} {} {} {} {} {} {LY} (3-Chloroprop-1-en-1-yl)benzene {} {} {} {} {} {} {} {} {LY} (3-Chloroprop-1-en-1-yl)benzene {} {} {} {} {} {} {} {} {} {LY} (3-Chloroprop-1-en-1-yl)benzene {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {LY} (3-Chloroprop-1-en-1-yl)benzene {} {} {} {} {} {} {} {} {} {} {} {LY} (3-Chloroprop-1-en-1-yl)benzene {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} (3-Chloroprop-1-en-1-yl)benzene {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} (3-Chloroprop-1-en-1-yl)benzene {} {} {} {} {}
MDL Number	MFCD00000986
CAS Number	2687-12-9
EC Number	220-246-4
Beilstein Registry Number	741974
PubChem Substance ID	639658
Chemical Name Translation	肉桂基氯
Reaxys-RN	741974
InChIKey	IWTYTFSSTWXZFU-UHFFFAOYSA-N
InChI	InChI=1S/C9H9Cl/c10-8-4-7-9-5-2-1-3-6-9/h1-7H,8H2/b7-4+
Canonical SMILES	ClC/C=C/C1=CC=CC=C1

信息真实价格透明资金保障专业采购外包团队在线服务

品牌质保精细包装现货库存一流品牌服务

产品应用

Usually used in the enantioselective total synthesis of helioporins C and E, bioactive marine diterpenes.

安全信息

RTECSCZ0919905

Packing GroupII

UN Number 1760 2927

Risk Statements

R22 Harmful if swallowed 吞咽有害
R26 Very toxic by inhalation 吸入极毒
R34 Causes burns 会导致灼伤
R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应

Safety Statements

S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后，立即用大量…（由生产厂家指定）冲洗；
S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；

GHS Symbol

WGK Germany3

Hazard statements

H227 Combustible liquid 可燃液体
H302 Harmful if swallowed 吞食有害
H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
H317 May cause an allergic skin reaction 可能导致皮肤过敏
H318 Causes serious eye damage 严重伤害眼睛
H330 Fatal if inhaled 吸入致命
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled 吸入可能导致过敏或哮喘症状或呼吸困难

Personal Protective Equipment Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

Precautionary statements

P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
P233 Keep container tightly closed. ?保持容器密闭。
P234 Keep only in original container. 只保留在原来的容器中。
P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P264+P265
P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
P272 Contaminated work clothing should not be allowed out of the workplace. 污染的工作服不得带出工作场所。
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P284 Wear respiratory protection.? 佩戴呼吸保护装置。
P285 In case of inadequate ventilation wear respiratory protection. 在通风不足的情况下，戴呼吸防护。
P301+P312
P301+P317
P301+P330+P331
P301+P330+P331+P310
P302+P352
P302+P361+P354
P303+P361+P353
P303+P361+P353+P310+P363
P304+P340
P304+P340+P310
P304+P341
P305+P351+P338
P305+P351+P338+P310
P305+P354+P338
P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
P316
P317
P320 Specific treatment is urgent (see … on this label). 紧急具体治疗（见本标签上的）。
P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
P330 Rinse mouth. 漱口
P333+P313
P342+P311
P342+P316
P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
P370+P378
P390 Absorb spillage to prevent material damage. 吸收溢出物，防止重大损害。
P403 Store in a well-ventilated place. 储存在通风良好的地方。
P403+P233
P403+P235
P405 Store locked up. 上锁保管。
P406 Store in corrosive resistant/… container with a resistant inner liner. 存放在耐腐蚀/具有耐性的内衬容器。
P501 Dispose of contents/container to..… 处理内容物/容器.....

Signal word Danger

Hazard Codes 8 T+ Xn

Hazard Class6.1/8

Storage condition 2-8°C {LY} 2-8°C Refrigerator (+4°C) {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY}

其他信息

肉桂基氯价格(试剂级):更新日期产品编号产品名称包装价格 2014/06/02 C1235 肉桂基氯 Cinnamyl Chloride 25G 396元 2010/06/21 181851000 肉桂基氯 Cinnamyl chloride , 95% trans 100 GR 1055元 2010/06/21 181850050 肉桂基氯 Cinnamyl chloride , 95% trans 5 GR 276元
用途一:用于有机合成
用途二:用于医药中间体，有机合成。
TCI Shanghai:肉桂基氯 Cinnamyl Chloride,>;95.0%(GC)(2687-12-9)
Acros Organics:肉桂基氯 Cinnamyl chloride, 95% trans(2687-12-9)
制备镇痛剂强痛定:由六水哌嗪酰化，与肉桂基氯缩合，再经水解、酰化、成盐制得非麻醉性镇痛剂强痛定，可用于治疗神经痛、术后疼痛、腰疼、灼烧后疼痛、排尿痛及肿瘤痛等症。
Hazard Note:Corrosive/Lachrymatory
Alfa Aesar:肉桂基氯,95%,碳酸钠作稳定剂 Cinnamyl chloride, 95%, stab. with sodium carbonate(2687-12-9)
方法一:由苯乙烯经氯甲基化而得。将盐酸、甲醛加入反应锅中，搅拌下加入苯乙烯，加热回流3h。静置1h，分去下层废酸，上层反应液加无水氯化钙脱水，得肉桂基氯。
下游产品:桂利嗪
MOL 文件:2687-12-9.mol
Sigma Aldrich:2687-12-9(sigmaaldrich)
MSDS 信息:Cinnamyl chloride(2687-12-9).msds
概述:肉桂基氯又名3-氯-1-苯丙烯、氯化肉桂酰。针状结晶或无色液体。分子量152.62。熔点8～9℃。沸点125～126℃ (2.93千帕)。相对密度 1.0926。折射率1.5851。闪点79℃。能与醇、醚任意混溶，溶于丙酮、苯，不溶于水。用于医药中间体。由苯乙烯经氯甲基化而得肉桂基氯，再同乌洛托品加热反应等都能制取芳香族醛--桂醛。桂醛主要用作食用香料，配制肉桂、薄荷、苹果、樱桃、李、杏、可乐、玫瑰、铃兰等香型香精，用于调味品、酒类、糖果、肉类，是我国GB 2760—1996规定允许使用的食用香料;也用于化妆品、牙膏和嗽口水;药用香料;本品还用作防腐剂和杀菌剂的原料。
上游原料:无水氯化钙 --> 苯乙烯
制备负型光刻胶聚乙烯醇肉桂酸酯:由肉桂酸及氯化亚砜在反应釜内60～65℃下制得肉桂基氯。然后将处理好的聚乙烯醇放入95～100℃溶剂吡啶中膨润、加入酯化釜内于50℃温度下滴加肉桂酰氯进行酯化反应，反应5小时后再加丙酮稀释、在水中沉淀，经过洗净、干燥后即得粗品。粗品在溶解釜内用环己酮及5-硝基苊溶解、过滤除去不溶杂质后生成产品。聚乙烯醇肉桂酸酯为负型光刻胶，被紫外光照射的部分会引起聚合物分子间交联不溶于显影剂。用于制备集成电路、电子元件，在光刻工艺中做抗蚀涂层。并适用于印刷线路板、金属标牌、光学仪器、精密量具生产中的微细图形加工。
敏感性:Lachrymatory