1,3-Dichloroacetone NBS*1,3-ELBT
CAS 534-07-6 MFCD00000937
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信息真实价格透明
资金保障
专业采购外包团队在线服务
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分类
- {uni_hamburg} no charge; ketone; 1fragment
- {SNA} Building Blocks, C3 to C6, Carbonyl Compounds, Chemical Synthesis, Ketones, Organic Building Blocks
- Building Blocks, C3 to C6, Carbonyl Compounds, Chemical Synthesis, Ketones, Organic Building Blocks
相关文献及参考
- Merck 14 ,3052
- Beil. 1 ,655
- Fieser 2 ,109
- Aldrich MSDS 1 , 601:D / Corp MSDS 1 (1), 1109:D / FT-IR 2 (1), 656:B / FT-IR 1 (1), 417:A / FT-NMR 1 (1), 650:C / IR-Spectra (3), 247:G / IR-Spectra (2), 221:D / NMR-Reference 2 (1), 380:D / RegBook 1 (1), 457:J / Sax 6 , 464 / Structure Index 1 , 65:A:5 / Vapor Phase 3 , 505:A
- Successive reaction with a Grignard reagent and Li metal leads to 1-substituted cyclopropanols, which rearrange on thermolysis to ethyl ketones: Synthesis, 647 (1983):
- The cyclization can also be induced by ethyl radicals, generated from ethylmagnesium bromide and FeCl3. This method is applicable only to 1-arylcyclopropanols: J. Org. Chem., 29, 2813 (1964); 43, 3602 (1978); Org. Synth. Coll., 5, 1058 (1973).
- Formation of the acetal followed by treatment with NaNH2 provides a route to cyclopropenones: Tetrahedron, 48, 2045 (1992).
- Short: II/14a Title: Molecular Constants: Diamagnetic Molecules Author: Demaison, J.; Dubrulle, A.; Hüttner, W.; Tiemann, E. Editor: Hellwege, K.-H.; Hellwege, A.M. Source: Landolt-Börnstein, New Series Volume: II/14a Page: 1-788 Year: 1982 Keyword: organic compounds; molecular constants; spectroscopy; microwave spectroscopy ISBN: 3-540-11365-7 ISBN: 978-3-540-11365-2 Internet Resource: DOI:10.1007/b19966 RefComment: 196 figs., XI
- Short: II/2 Title: Magnetic Properties of Coordination and Organometallic Transition Metal Compounds Author: König, E. Editor: Hellwege, K.-H.; Hellwege, A.M. Source: Landolt-Börnstein, New Series Volume: II/2 Year: 1966 ISBN: 3-540-03593-1 ISBN: 978-3-540-03593-0 Internet Resource: DOI:10.1007/b19948 RefComment: 170 figs., XII, 578 pages. Hardcover Abstract: The data compiled refer to susceptibility measurements (susceptibility, Curie-constants, magnetic moments, transition temperatures) and ESR-measurements (g-fac
安全信息
GHS Symbol



- H300+H310+H330
- H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
- H341 Suspected of causing genetic defects 怀疑导致遗传性缺陷
- P303+P361+P353+P310+P363
- P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
- P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P284 Wear respiratory protection.? 佩戴呼吸保护装置。
- P501 Dispose of contents/container to..… 处理内容物/容器.....
- P405 Store locked up. 上锁保管。
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P301+P310
- P302+P350
- P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛,皮肤或衣服。
- P403+P233
- P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
- P304+P340+P310
- P305+P351+P338+P310
- P301+P330+P331+P310
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- R24 Toxic in contact with skin 与皮肤接触有毒
- R26/28 Very toxic by inhalation and if swallowed 吸入及吞食都有剧毒
- R68 Possible risk of irreversible effects 可能有不可挽回的作用的危险
- R34 Causes burns 会导致灼伤
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
- S1 Keep locked up 上锁;
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
- S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后,立即用大量…(由生产厂家指定)冲洗;
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
- S20 When using do not eat or drink 使用时,不得进食,饮水;
- S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
- S4 Keep away from living quarters 远离生活区;
- S9 Keep container in a well-ventilated place 保持容器在通风良好的场所;
- S27/28
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 37500 ug/kg TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors REFERENCE : CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 48,197,1989
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 20 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) REFERENCE : NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0555373
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 18900 ug/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - somnolence (general depressed activity) REFERENCE : NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(iss
TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 29 mg/m3/2H TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,44,1982
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 53 mg/kg TOXIC EFFECTS : Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Sense Organs and Special Senses (Eye) - iritis Behavioral - somnolence (general depressed activity) REFERENCE : NTIS** National Technical Information Service. (Springfield, VA 22161)
TYPE OF TEST : Mutation test systems - not otherwise specified TEST SYSTEM : Bacteria - Escherichia coli DOSE/DURATION : 300 ug/L REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 341,1,1994
TYPE OF TEST : Gene conversion and mitotic recombination TEST SYSTEM : Yeast - Saccharomyces cerevisiae DOSE/DURATION : 1 ug/L REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 155,53,1985
TYPE OF TEST : Micronucleus test ROUTE OF EXPOSURE : Multiple routes TEST SYSTEM : Non-mammalian species DOSE/DURATION : 50 ug/L REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 341,1,1994
TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 1250 ng/plate REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 157,111,1985
TYPE OF TEST : Sister chromatid exchange TEST SYSTEM : Rodent - hamster Lung DOSE/DURATION : 2 umol/L REFERENCE : ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 9,401,1987
TYPE OF TEST : Sex chromosome loss and nondisjunction ROUTE OF EXPOSURE : Inhalation TEST SYSTEM : Insect - Drosophila melanogaster DOSE/DURATION : 100 pph/8M REFERENCE : PREBA3 Proceedings of the Royal Society of Edinburgh, Section B.
其他信息
- 蒸气密度:4.38 (vs air)
- 急性毒性:吸入-大鼠 LC50: 29 毫克/立方米/2 小时; 吸入-小鼠 LC50: 27 毫克/立方米/2小时
- 1,3-二氯丙酮价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 80045024 1,3-二氯丙酮(剧毒) 25g 280元 2010/06/21 173630500 1,3-二氯丙酮 1,3-Dichloroacetone 99% 50 GR 833元 2010/06/21 173632500 1,3-二氯丙酮 1,3-Dichloroacetone 99% 250 GR 3289元
- 灭火剂:泡沫、二氧化碳、抗溶性泡沫、砂土。
- 方法一:由1,3-二氯丙醇与重铬酸钠反应而得。
- 上游原料:环氧氯丙烷 --> 重铬酸钠 --> 1,3-二氯丙醇
- 职业标准:STEL 0.05 毫克/立方米
- 用途一:是重要的医药、农药中间体,目前主要用于喹诺酮类抗菌药环丙氟哌酸的合成
- 类别:有毒物品
- 外观性质:无色结晶。
- MSDS 信息:1,3-二氯丙酮(534-07-6).msds
- 海关编码:29147090
- 蒸气压:<;0.1 mm Hg ( 20 °C)
- Sigma Aldrich:534-07-6(sigmaaldrich)
- 用途二:作有机合成中间体。
- 可燃性危险特性:明火可燃;受热分解产生氯化物气体;与氧化剂起作用
- 图谱信息:1,3-二氯丙酮(534-07-6)红外图谱(IR2) 1,3-二氯丙酮(534-07-6)核磁图( 13 CNMR) 1,3-二氯丙酮(534-07-6)红外图谱(IR3) 1,3-二氯丙酮(534-07-6)质谱(MS) 1,3-二氯丙酮(534-07-6)核磁图( 1 HNMR) 1,3-二氯丙酮(534-07-6)Raman光谱 1,3-二氯丙酮(534-07-6)红外图谱(IR1)
- 下游产品:尼扎替丁 --> 氟康唑 --> (2-(三氟甲基)噻唑-4-基) 甲胺 --> 5-氯-4-氯甲基-1,2,3-噻二唑 --> 法莫替丁 --> (S)-((2-胍基-4-噻唑基)甲基)异硫脲二盐酸盐 --> 3-(2-胍基-噻唑-4-基甲硫)-丙腈
- 储运特性:库房通风低温干燥; 与氧化剂、食品添加剂分开存放
- Acros Organics:1,3-二氯丙酮 1,3-Dichloroacetone,99%(534-07-6)
- F:19
- 毒性分级:高毒
- Alfa Aesar:1,3-二氯丙酮,typically99% 1,3-Dichloroacetone, typically 99%(534-07-6)
- MOL 文件:534-07-6.mol