CAS 78-87-5 MFCD00000868-1,2-Dichloropropane 1,2-二氯丙烷 TAO{mole}

1,2-Dichloropropane 1,2-二氯丙烷

CAS 78-87-5 MFCD00000868

化学结构图

SMILES: CC(Cl)CCl

化学属性

Mol. Formula	C3H6Cl2
Mol. Weight	113
Autoignition Point	1035 °F
Refractive index	1.4380 to 1.4400
Vapor Density	3.89 (vs air)
Boiling Point	97°C
Vapor Pressure	40 mmHg ( 19.4 °C)
Density	1.156
Melting Point	-100°C
Flash Point	14°C(lit.)
TSCA	Yes
Solubility	3 G/L (20 ºC)
Appearance	无色透明液体，可燃。能与水、醇、醚、酯、苯、三氯甲烷和芳香化合物等有机溶剂任意混合。冰点-20℃，沸点166℃，96℃（10.7kPa），85-87℃（4.4kPa），74-74.5℃（3.47kPa），66-67℃（2.0kPa），62-63℃（1.6kPa），相对密度0.9366（25/4℃），0.9599（0/4℃），折射率1.4380。闪点（开杯）70℃。

别名和识别编码

Chemical Name	1,2-Dichloropropane
Synonym	CH3CON(CH3)2 Pr bichloruredepropylene n,n-dimethylacetamides { 1,2-二氯丙烷;氯化丙烯 (±)-1,2-dichloro-propane {Chemica 1,2-二氯丙烷 {Chemi 1,2-Dichlorpropan {Chemicalb SK 7176 PROPYLENE DICHLORIDE 乙酰二甲胺 Chlorinated C3 hydrocarbons bichloruredepropylene(french) 1,2-Dichloropropane Acetic acid dimethylacetamide NSC 3138 Bichlorure de propylene B 二氯丙烷 α,β-Dichloropropane nsc3138 N-乙酰二甲胺 {C N,N-二甲基乙酰胺, HPLC GRADE, 99.5+% 氯化丙烯 D-d Mixture alpha,beta-Propylene dichloride dichloro-1,2-propane NCI-C55141 1,2-二氯丙烷, 98%
MDL Number	MFCD00000868
CAS Number	78-87-5
PubChem Substance ID	87567081
EC Number	201-152-2
Beilstein Registry Number	1(4)195
Merck Number	7854
Reaxys-RN	1718880
Chemical Name Translation	1,2-二氯丙烷
Wiswesser Line Notation	GY1&1G
LabNetwork Molecule ID	LN00223891

信息真实价格透明资金保障专业采购外包团队在线服务

品牌质保精细包装现货库存一流品牌服务

产品应用

油类和脂肪的溶剂。干洗剂。脱脂剂。杀虫熏蒸混合剂。

安全信息

GHS Symbol

WGK Germany3

Hazard statements

H332 Harmful if inhaled 吸入有害
H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
H302 Harmful if swallowed 吞食有害
H302+H332

Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

RTECSTX9625000

Precautionary statements

P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P305+P351+P338
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P501 Dispose of contents/container to..… 处理内容物/容器.....
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
P301+P312+P330
P337+P313
P403+P233
P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P303+P361+P353
P201 Obtain special instructions before use. 使用前获取专门指示。
P302+P352+P333+P313+P362+P364
P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
P233 Keep container tightly closed. ?保持容器密闭。
P304+P340+P312
P273 Avoid release to the environment. 避免释放到环境中。
P305+P351+P338+P337+P313
P308+P311

Signal word

Packing GroupII

UN Number 1279

Risk Statements

R20/22 Harmful by inhalation and if swallowed 吸入和不慎吞咽有害
R11 Highly flammable 非常易燃
R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入，皮肤接触及吞食都有毒
R23/25 Toxic by inhalation and if swallowed 吸入及吞食都有毒
R39/23/24/25 Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed 毒性：吸入，皮肤接触和吞食都会产生十分严重的不可逆危险
R61 May cause harm to the unborn child 可能对未出生的婴儿导致伤害
R20/21 Harmful by inhalation and in contact with skin 吸入及与皮肤接触有害

Safety Statements

S24 Avoid contact with skin 避免皮肤接触；
S16 Keep away from sources of ignition - No smoking 远离火源，禁止吸烟；
S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
S53 Avoid exposure - obtain special instructions before use 避免接触，使用前获得特别指示说明；
S2 Keep out of the reach of children 避免儿童触及；

Hazard Codes F,Xn,T

Storage condition 0-6°C Refrigerator 储存温度2-8℃ 密封阴凉保存。 0-10°C 0-10

Hazard Class3

Warnings 危化品目录(2015) 危险化学品

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 130 gm/kg/2Y-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Skin and Appendages - tumors
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-263,1986

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 5 gm/kg
TOXIC EFFECTS :
   Behavioral - sleep
   Liver - other changes
REFERENCE :
   AJHYA2 American Journal of Hygiene.  (Baltimore, MD)  V.1-80, 1921-64.  For
   publisher information, see AJEPAS.  Volume(issue)/page/year: 16,325,1932

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 960 mg/kg
TOXIC EFFECTS :
   Gastrointestinal - ulceration or bleeding from stomach
   Gastrointestinal - ulceration or bleeding from small intestine
REFERENCE :
   ESKGA2 Eisei Kagaku.  Hygienic Chemistry.  (Nippon Yakugakkai, 2-12-15
   Shibuya, Shibuya-ku, Tokyo 150, Japan)  V.1-    1953-
   Volume(issue)/page/year: 28,P31,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rod

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FMCHA2 Farm Chemicals Handbook.  (Meister Pub., 37841 Euclid Ave.,
   Willoughy, OH 44094)  Volume(issue)/page/year: -,C253,1991

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 860 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
   Prague, Czechoslovakia, Avicenum, 1986  Volume(issue)/page/year: -,98,1986

TYPE OF TEST            : LCLo - Lowest

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 100 ug/plate
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 5(Suppl
   1),3,1983

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Rodent - mouse Lymphocyte
DOSE/DURATION           : 11600 ug/L
REFERENCE :
   SCIEAS Science.  (American Assoc. for the Advancement of Science, 1333 H
   St., NW, Washington, DC 20005)  V.1-    1895-  Volume(issue)/page/year:
   236,933,1987

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 660 mg/L
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-263,1986

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 3300 umol/L
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 9,401,1987

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 113 mg/L
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   10(Suppl 10),1,1987

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE                    : 1950 mg/kg
SEX/DURATION            : female 7-19 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Maternal Effects - other effects
REFERENCE :
   FAATDF Fundamental and Applied Toxicology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1981-  Volume(issue)/page/year:
   28,18,1995

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 1250 mg/kg
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Maternal Effects - other effects
REFERENCE :
   FAATDF Fundamental and Applied Toxicology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1981-  Volume(issue)/page/year:
   28,18,1995

其他信息

下游产品:4-氟苯胺 --> 二苯基乙炔 --> 1-硫代磺酸钠基
用途四:用于药物合成的反应溶剂，合成纤维纺丝与合成树脂的溶剂，感光化学品发色剂的溶剂，涂料等的溶剂。催化剂。
蒸气密度:3.89 (vs air)
F:
毒性分级:中毒
MSDS 信息:1,2-二氯丙烷(78-87-5).msds
Alfa Aesar:N,N-二甲基乙酰胺,HPLCGrade,99.5+% N,N-Dimethylacetamide, HPLC Grade, 99.5+%(127
MOL 文件:127-19-5.mol
方法一:由丙烯与氯气在二氯丙烷中液相低温氯化
用途二:用作有机合成原料，油类、脂肪的溶剂，洗涤剂，树脂、农药的原料。经氨化可制得丙二胺。1,2-二氯丙烷和1,3-二氯丙烯，作为农药即滴滴混剂、D-D、Vidden D，[8003-19-8]。D-D为播前杀线虫剂，能有效地防治土壤线虫，包括根瘤线虫、草地线虫、刺线虫、剑线虫、螺旋线虫和甜菜线虫。当药剂施入15-20cm土壤深
有害影响和中毒症状:经常暴露于二甲基乙酰胺中的工人，观察到黄疸、肝损伤，但一般可迅速恢复。有人用本品作为抗癌药而大剂量口服时，引起的症状有抑郁、嗜眠、视听幻觉; 还可能出现心、肾和脑变性。DMA对鼠胚胎有毒性作用，对兔有致畸作用。
医学监护:就
Acros Organics:N,N-二甲基乙酰胺 N,N-Dimethylacetamide, extra pure, 99.5%(127-19-5)
下游产品:1,2-丙二胺 --> 杀虫环 --> 1,3-二氯丙烯 --> 四氯丙烯 --> 2-氯丙酰氯
1,2-二氯丙烷价格(试剂级):更新日期产品编号产品名称包装价格 2014/06/02 S0634 1,2-二氯丙烷(1mg/ml的甲醇溶液)[用于水分析] 1,2-Dichloropropane (1mg/ml in Methanol) [for Water Analysis] 1ML 240元 2014/06/02 D0398 1,2-二氯丙烷 1,2-Dichloropropane 25G 159元 2014/06/02 D0398 1,2-二氯丙烷 1,2-Dichloropropane 500G 658元
MOL 文件:78-87-5.mol
上游原料:N,N-二甲基乙
爆炸物危险特性:与空气混合可爆
灭火剂:泡沫、干粉、二氧化碳
概述:N,N-二甲基乙酰胺又称乙酰基二甲胺、乙酰二甲胺，简称DMAC，是一种非质子高极性溶剂，有微氨气味，溶解力很强，可溶解的物质范围很广，能与水、芳香族化合物、酯、酮、醇、醚、苯和三氯甲烷等任意混溶，且能使化合物分子活化，因此广泛用作溶剂及催化剂。在溶剂方面作为高沸点、高闪点、热稳定性高、化学性
MSDS 信息:Acetdimethylamide(127-19-5).msds
外观性质:无色液体，有类似氯仿的气味。
Alfa Aesar:1，2-二氯丙烷,98% 1,2-Dichloropropane, 98%(78-87-5)
N,N-二甲基乙酰胺价格(试剂级):更新日期产品
有氯仿气味。微溶于水，水中溶解度: 3 g/L (20°C) ，溶于大多数常规有机溶剂。易燃。低毒，半数致死量（大鼠，经口）1900mg/kg。有刺激性。
Sigma Aldrich:78-87-5(sigmaaldrich)
可燃性危险特性:遇明火、高温、强氧化剂可燃; 燃烧排放有毒氮氧化物烟雾
海关编码:29241900
上游原料:N,N-二甲基乙酰胺 --> 丙烯
职业标准:TWA 350 毫克/ 立方米