2-Chlorobenzoyl Chloride 2-氯苯甲酰氯(易涉毒)
CAS 609-65-4 MFCD00000660
化学结构图
SMILES: O=C(Cl)c1ccccc1Cl
化学属性
| Mol. Formula | C7H4Cl2O |
|---|---|
| Mol. Weight | 175 |
| Density | 1.382 |
| Refractive index | 1.5710 to 1.5730 |
| Boiling Point | 238 |
| Melting Point | -4 - -3 |
| Flash Point | 124°C(lit.) |
| TSCA | Yes |
| Stability | 对湿度敏感 |
| Appearance | D 1.5718，相对密度 1.382，溶于有机溶剂，遇水分解。 邻氯苯甲酰氯是黄色液体，m.p.-4～-3℃，b.p.238℃，n 20 |
别名和识别编码
| Chemical Name | 2-Chlorobenzoyl Chloride |
|---|---|
| Synonym | 2-Chloro benzoyl chloride OCOC 2-氯苯甲酰氯 Benzoyl chloride, o-chloro- 2-Chlorbenzoesäurechlorid 2-氯苯甲酰氯,97% 2-Chlorobenzoylchloride,97% 氯苯甲醯氯 O-CHLOROBENZOYL CHLORIDE o-Chlorobenzoyl chloride Benzoyl chloride, 2-chloro- (9CI) 47) ORTHO CHLORO BENZOYL CHLORIDE 2-chloro-benzoylchlorid 2-Chlor-benzoylchlorid 2-Chlorbenzoylchlorid 邻氯化苯甲酰氯 benzoyl chloride, 2-chloro- OCOC; 2-Chlorobenzoic acid chloride 2-chlorobenzoyl chloride 2-CHLOROBENZOIC ACID CHLORIDE Benzoylchloride,2-chloro- 2-chloro-benzoyl chloride Benzoyl chloride, o-chloro- o-Chlorbenzoylchlorid 2-chlorobenzoic acid chloride 2-Chlorobenzoyl Chloride o-Chlorobenzoyl Chloride chlorobenzoylchloride o-Chlorobenzonyl chloride 2-氯苯甲酰氯(邻氯苯甲酰氯) 氯化邻氯苯甲酰 邻氯苯甲酰氯 LABOTEST-BB LTBB000568 o-Chlorbenzoylchlorid 2-CHLOROBENZOYL CHLORIDE 邻氯化苯甲酰氯,2-氯苯甲酰氯,氯化邻氯苯甲酰 |
| MDL Number | MFCD00000660 |
| CAS Number | 609-65-4 |
| EC Number | 210-194-0 |
| Beilstein Registry Number | 386435 |
| PubChem Substance ID | 69110 |
| Reaxys-RN | 386435 |
| Chemical Name Translation | 2-氯苯甲酰氯(易涉毒) |
| InChIKey | ONIKNECPXCLUHT-UHFFFAOYSA-N |
| LabNetwork Molecule ID | LN00193508 |
| InChI | InChI=1S/C7H4Cl2O/c8-6-4-2-1-3-5(6)7(9)10/h1-4H |
信息真实价格透明
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信息真实价格透明
资金保障
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现货库存
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分类
- {uni_hamburg} no charge; carbocycle; aromatic; 6RingOnly; 6ring; carbonyl chloride; 1fragment
- {SNA} Acid Halides, Building Blocks, Carbonyl Compounds, Chemical Synthesis, Organic Building Blocks
产品应用
- 医药及染料中间体。用于全身麻醉药氯胺酮盐酸盐；非麻醉性镇咳药敌退咳等的生产。
相关文献及参考
- Can be used to introduce a carboxyl group into an aromatic ring by Friedel-Crafts acylation, followed by cleavage of the resulting ketone with KO-t-Bu. With this aryl group, cleavage occurs in only one of the two possible senses. For an example, (ferrocenecarboxylic acid), see: Org. Synth. Coll., 6, 625 (1988).
- Short: III/35E
- Short: III/20b
- Short: III/38B
- Beilstein:9,336
安全信息
GHS Symbol
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
- R34 Causes burns 会导致灼伤
- P201 Obtain special instructions before use. 使用前获取专门指示。
- P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P304+P340
- P304+P340+P310
- P305+P351+P338
- P305+P351+P338+P310
- P308+P313
- P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
- P501 Dispose of contents/container to..… 处理内容物/容器.....
- H290 May be corrosive to metals 可能腐蚀金属。
- H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
其他信息
- 溶于醇，醚，丙酮，不溶于水。遇水分解。
- 上游原料:苄基氯 --> 2-氯苯甲酸
- 用途一:主要用于克霉唑等的中间体及邻氯苯甲酸的制备和三氯杀螨剂的生产
- MSDS 信息:2-Chlorobenzoic acid chloride(609-65-4).msds
- 方法二:由邻氯苯甲酸与氯化亚砜反应而得：将邻氯苯甲酸与氯化亚砜搅拌加热溶解，升温回流0.5h。然后蒸去过量的氯化亚砜，再进行常压蒸馏，收集220-230℃馏分而得粗品，最后减压蒸馏而得成品。收率为85%-90%。
- MOL 文件:609-65-4.mol
- 用途二:用作有机合成中间体
- Acros Organics:2-氯苯甲酰氯 2-Chlorobenzoyl chloride, 98%(609-65-4)
- 方法一:其制法可用 α，α，α，2-四氯甲苯直接水解得到或用邻氯苯甲酸和酰氯化剂 SOCl 2 、PCl 3 等酰氯化可得产品，
- 邻氯苯甲酰氯价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 80032826 2-氯苯甲酰氯;氯化邻氯苯甲酰;邻氯苯甲酰氯 100ml 46元 2011/04/16 C0140 2-氯苯甲酰氯 2-Chlorobenzoyl Chloride 500ML 909元 2011/04/16 C0140 2-氯苯甲酰氯 2-Chlorobenzoyl Chloride 25ML 160元
- TCI Shanghai:2-氯苯甲酰氯 2-Chlorobenzoyl Chloride,>;95.0%(GC)(T)(609-65-4)
- 下游产品:2-氯苯甲酸 --> 灭幼脲 --> 克霉唑 --> 四螨嗪 --> 氯氨酮相关物质A --> 2'-氯苯基乙酮 --> 邻氯苯基环戊基酮 --> 氯安定 --> 2-氯二苯甲酮 --> 2-氯苯甲酰胺 --> 2-氯-4'-氟二苯甲酮 --> 7-溴-5-(2-氯苯基)-2,3-二氢-2-(甲氧基甲基)-1-甲基-1H-1,4-苯并二氮杂卓 --> 氯苯嘧啶醇
- 用途四:医药及染料中间体。用于全身麻醉药氯胺酮盐酸盐、非麻醉性镇咳药敌退咳等的生产。
- 海关编码:29163900
- 图谱信息:邻氯苯甲酰氯(609-65-4)红外图谱(IR2) 邻氯苯甲酰氯(609-65-4)Raman光谱 邻氯苯甲酰氯(609-65-4)核磁图( 13 CNMR) 邻氯苯甲酰氯(609-65-4)核磁图( 1 HNMR) 邻氯苯甲酰氯(609-65-4)质谱(MS) 邻氯苯甲酰氯(609-65-4)红外图谱(IR1)
- Sigma Aldrich:609-65-4(sigmaaldrich)
- 用途五:医药及染料中间体。用于全身麻醉药氯胺酮盐酸盐；非麻醉性镇咳药敌退咳等的生产。
- Hazard Note:Corrosive/Moisture Sensitive
- Alfa Aesar:2-氯苯甲酰氯,97% 2-Chlorobenzoyl chloride, 97%(609-65-4)
- 用途三:邻氯苯甲酰氯是苯甲酰脲类杀虫剂杀铃脲和灭幼脲的中间体，也是杀螨剂四螨嗪和杀菌剂氟苯嘧啶醇的中间体。
- 存储注意事项:湿度敏感
- 敏感性:Moisture Sensitive
- F:19-21
