Tideglusib 泰格列净
CAS 865854-05-3 MFCD18633296
化学结构图
SMILES: O=c1[s][n](-c2cccc3ccccc32)c(=O)[n]1Cc1ccccc1
化学属性
| Mol. Weight | 334.39 |
|---|---|
| Mol. Formula | C19H14N2O2S |
别名和识别编码
| Synonym | 4-Benzyl-2-(naphthalen-1-yl)-[1,2,4]thiadiazolidine-3,5-dione 4-Benzyl-2-(naphthalen-1-yl)-[1,2,4]thiadiazolidine-3,5-dione NP-12 NP031112 NP-12 NP031112 |
|---|---|
| CAS Number | 865854-05-3 |
| InChIKey | PMJIHLSCWIDGMD-UHFFFAOYSA-N |
| Chemical Name | Tideglusib |
| MDL Number | MFCD18633296 |
| PubChem Substance ID | 329825344 |
| Chemical Name Translation | 泰格列净 |
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分类
- Alzheimer′s Disease, Assays/Reagents for Alzheimer′s Disease Research, Cell Biology, Cell Signaling and Neuroscience, Glycogen Synthase Kinase 3 (GSK3), Kinase/Phosphatase Biology, Neurobiology, Neuroscience, New Products, Products for Neurodegenerative Disease Research, Serine/Threonine Kinase Biology,
相关文献及参考
- Luna-Medina, R., et al., NP031112, a thiadiazolidinone compound, prevents inflammation and neurodegeneration under excitotoxic conditions: potential therapeutic role in brain disorders. J. Neurosci. 27 , 5766-5776, (2007)
- Martinez, A., et al., Glycogen synthase kinase 3 inhibitors in the next horizon for Alzheimer's disease treatment. Int. J. Alzheimers Dis. Jun. 30 , (2011)
- Medina, M., et al., Modulation of GSK-3 as a Therapeutic Strategy on Tau Pathologies. Front. Mol. Neurosci. Oct. 11 , (2011)
