Cicloprololum[Latin] 1-[4-[2-(环丙基甲氧基)乙氧基]苯氧基]-3-[(异丙基)氨基]-2-丙醇盐酸盐

CAS 63686-79-3 MFCD N/A

化学结构图

63686-79-3
SMILES:

化学属性

Mol. FormulaC18H29NO4.ClH
Mol. Weight359.94

别名和识别编码

Chemical Name2-Propanol,1-(4-(2-(cyclopropylmethoxy)ethoxy)phenoxy)-3-((1-methylethyl)amino)-, hydrochloride
Chemical Name Translation1-[4-[2-(环丙基甲氧基)乙氧基]苯氧基]-3-[(异丙基)氨基]-2-丙醇盐酸盐
Chemicalbook IDCB11246781
Wiswesser Line NotationL3TJ A1O2OR DO1YQ1MY1&1 &GH
Synonym 1-(4-(2-(Cyclopropylmethoxy)ethoxy)phenoxy)-3-isopropylaminopropan-2-ol
CAS Number63686-79-3
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相关文献及参考

  • [2]. Cocco G, et al. An evaluation of the safety of the beta-modulator cicloprolol in chronic heart failure. Clin Cardiol. 1992 Jan;15(1):38-42.
  • [1]. Weber S, et al. Pharmacodynamic without pharmacokinetic interaction between cicloprolol, a partial beta 1-adrenoceptor agonist, and digoxin in healthy subjects. Br J Clin Pharmacol. 1990 Sep;30(3):411-6
  • [1]. Weber S, et al. Pharmacodynamic without pharmacokinetic interaction between cicloprolol, a partial beta 1-adrenoceptor agonist, and digoxin in healthy subjects. Br J Clin Pharmacol. 1990 Sep;30(3):411-6
  • [2]. Cocco G, et al. An evaluation of the safety of the beta-modulator cicloprolol in chronic heart failure. Clin Cardiol. 1992 Jan;15(1):38-42.

安全信息

RTECSUA9822000
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 610 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4252984

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 76 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4252984

系列性分类


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