Pj34 Hydrochloride N-(6-氧代-5,6-二氢菲啶-2-基)-2-(N,N-二甲基氨基)乙酰胺盐酸盐
CAS 344458-15-7 MFCD44458157
化学结构图
SMILES:
化学属性
| Mol. Weight | 331.80 (anhydrous basis) |
|---|---|
| Mol. Formula | C17H17N3O2· HCl · xH2O |
别名和识别编码
| CAS Number | 344458-15-7 |
|---|---|
| Chemical Name | Pj34 Hydrochloride |
| Synonym | N-(5,6-Dihydro-6-oxo-2-phenanthridinyl)-2-(dimethylamino)acetamide N-(6-Oxo-5,6-dihydrophenanthridin-2-yl)-(N,N-dimethylamino)acetamide hydrochloride |
| PubChem Substance ID | 24898531 |
| Chemical Name Translation | N-(6-氧代-5,6-二氢菲啶-2-基)-2-(N,N-二甲基氨基)乙酰胺盐酸盐 |
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资金保障
专业采购外包团队在线服务
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分类
- Apoptosis and Cell Cycle, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, P, P to Q, PARP (Poly(ADP-Ribose) polymerase), PARP Inhibitors, PARP Poly(ADP-ribose) Polymerase
- {SNA} Apoptosis and Cell Cycle,
- {SNA} Apoptosis and
- {SNA} Apoptosis and Cell Cycle, Bioactive Small Molecule Alphabetical Index, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, P to Q, PARP (Poly(ADP-Ribose) polymerase), PARP Inhibitors, PARP Poly(ADP-ribose) Polymerase, PI-PZ, 生化试剂,
产品应用
- A poly adenosine diphosphate-ribose polymerase inhibitor, attenuates chromate-induced nephrotoxicity.
相关文献及参考
- Barceloux, D., et al.: Clin. Toxicol., 37, 173
- Garcia Soriano, F., et al., Diabetic endothelial dysfunction: the role of poly(ADP-ribose) polymerase activation. Nat. Med. 7 , 108, (2001) 摘要
- Abdelkarim, G.E., Protective effects of PJ34, a novel, potent inhibitor of poly(ADP-ribose) polymerase (PARP) in in vitro and in vivo models of stroke. Int. J. Mol. Med. 7 , 255, (2001) 摘要
- Ba, X., et al., Trypanosoma Cruzi Induces The Reactive Oxygen Species-PARP-1-RelA Pathway For Up-regulation Of Cytokine Expression In Cardiomyocytes. J. Thorac. Cardiovasc. Surg. 285 , 11596-606, (2010)
