GLP-1R agonist
CAS 281209-71-0 MFCD81209710
化学结构图
SMILES:
化学属性
| Mol. Weight | 348.25 |
|---|---|
| Mol. Formula | C13H15Cl2N3O2S |
别名和识别编码
| Synonym | 2-Quinoxalinamine, 6,7-dichloro-N-(1,1-dimethylethyl)-3-(methylsulfonyl)- 2-Quinoxalinamine, 6,7-dichloro-N-(1,1-dimethylethyl)-3-(methylsulfonyl)- 6,7-dichloro-2-methylsulfonyl-3-N-tert-butylaminoquinoxaline (DMB) Compound 2 6,7-dichloro-2-methylsulfonyl-3-N-tert-butylaminoquinoxaline (DMB) Compound 2 |
|---|---|
| CAS Number | 281209-71-0 |
| Chemical Name | GLP-1R agonist |
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分类
- Cell Biology, Cell Signaling and Neuroscience, Cytokines, Growth Factors and Hormones, Hormones, Insulin and Insulin Receptors, Other Protein/Peptide Hormones
- {SNA} Bioactive Small Molecule Alphabetical Index, Cytokines, Growth Factors and Hormones, G, Hormones, Insulin and Insulin Receptors, Other Protein/Peptide Hormones,
相关文献及参考
- Irwin, N., et al., Insulin-releasing and metabolic effects of small molecule GLP-1 receptor agonist 6,7-dichloro-2-methylsulfonyl-3-N-tert-butylaminoquinoxaline. Eur. J. Pharmacol. 1-3 , 268-273, (2010) 摘要
- Koole, C., et al., Allosteric ligands of the glucagon-like peptide 1 receptor (GLP-1R) differentially modulate endogenous and exogenous peptide responses in a pathway-selective manner; implications for drug screening. Mol. Pharmacol. , (2010)
- Teng, M., et al., Small molecule ago-allosteric modulators of the human glucagon-like peptide-1 (hGLP-1) receptor. Bioorg. Med. Chem. Lett. 19 , 5472-5478, (2007) 摘要
安全信息
GHS Symbol
- H302 Harmful if swallowed 吞食有害
- R22 Harmful if swallowed 吞咽有害
