(R)-N-(2-((1-(4-Chlorobenzyl)Pyrrolidin-3-Yl)Amino)-2-Oxoethyl)-3-(Trifluoromethyl)Benzamide (R)-N-(2-((1-(4-氯苄基)吡咯烷-3-基)氨基)-2-代氧乙基)-3-(三氟甲基)苯甲酰胺
CAS 226226-39-7 MFCD26226397
化学结构图
SMILES:
化学属性
| Mol. Formula | C21H21CIF3O2.HCl |
|---|
别名和识别编码
| Chemical Name | (R)-N-(2-((1-(4-Chlorobenzyl)Pyrrolidin-3-Yl)Amino)-2-Oxoethyl)-3-(Trifluoromethyl)Benzamide |
|---|---|
| Chemicalbook ID | CB92518850 |
| Chemical Name Translation | (R)-N-(2-((1-(4-氯苄基)吡咯烷-3-基)氨基)-2-代氧乙基)-3-(三氟甲基)苯甲酰胺 |
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相关文献及参考
- [2]. Hall SE, et al. Elucidation of binding sites of dual antagonists in the human chemokine receptors CCR2 and CCR5. Mol Pharmacol. 2009 Jun;75(6):1325-36.
- [3]. Calin M, et al. VCAM-1 directed target-sensitive liposomes carrying CCR2 antagonists bind to activated endothelium and reduce adhesion and transmigration of monocytes. Eur J Pharm Biopharm. 2015 Jan;89:18-29.
- [1]. Moree WJ, et al. Potent antagonists of the CCR2b receptor. Part 3: SAR of the (R)-3-aminopyrrolidine series. Bioorg Med Chem Lett. 2008 Mar 15;18(6):1869-73.
- [1]. Moree WJ, et al. Potent antagonists of the CCR2b receptor. Part 3: SAR of the (R)-3-aminopyrrolidine series. Bioorg Med Chem Lett. 2008 Mar 15;18(6):1869-73.
- [2]. Hall SE, et al. Elucidation of binding sites of dual antagonists in the human chemokine receptors CCR2 and CCR5. Mol Pharmacol. 2009 Jun;75(6):1325-36.
- [3]. Calin M, et al. VCAM-1 directed target-sensitive liposomes carrying CCR2 antagonists bind
