AN-7
CAS 213262-83-0 MFCD13262830
化学结构图
SMILES: CCCC(=O)OCOP(=O)(OCC)OCC
化学属性
| Mol. Weight | 254.21732 |
|---|---|
| Appearance | Solid powder |
| Solubility | Soluble in DMSO, not in water |
别名和识别编码
| Chemical Name | AN-7 |
|---|---|
| Formula | C9H19O6P |
| Synonym | AN7; AN-7; AN 7; butyroyloxymethyl diethylphosphate |
| IUPAC Name | butyroyloxymethyl diethylphosphate |
| InChIKey | UGIGKLCVADLBRB-UHFFFAOYSA-N |
| InChI | InChI=1S/C9H19O6P/c1-4-7-9(10)12-8-15-16(11,13-5-2)14-6-3/h4-8H2,1-3H3 |
| Canonical SMILES | O=P(OCC)(OCOC(CCC)=O)OCC |
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产品应用
- AN-7 is a potent HDAC inhibitor, is also a prodrug of butyric acid, which induced histone hyperacetylation and differentiation and inhibited proliferation of human prostate 22Rv1 cancer cells in vitro and in vivo. AN-7 is likely to display a high therapeutic index and may be beneficial for prostate cancer patients.
