Sonepiprazole
CAS 170858-33-0 MFCD70858330
化学结构图
SMILES: CC(O)=O
化学属性
| Mol. Weight | 401.52 |
|---|---|
| Mol. Formula | C21H27N3O3S |
别名和识别编码
| CAS Number | 170858-33-0 |
|---|---|
| Chemical Name | Sonepiprazole |
| Synonym | 4-[4-[2-[(1S)-3,4-Dihydro-1H-2-benzopyran-1-yl]ethyl]-1-piperazinyl]benzenesulfonamide PNU 101387 U 101387 |
| Chemical Name Translation |
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资金保障
专业采购外包团队在线服务
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分类
- Aromatics
- Heterocycles
- Inhibitors
- Pfizer Compounds
- Pharmaceuticals
- Intermediates & Fine Chemicals
- Sulfur & Selenium Compounds
产品应用
- A selective D4 dopamine antagonist that exhibits low affinity at other monoamine receptors (Ki > 2000 nM). Induces c-fos gene expression in medial prefrontal cortex in a similar manner to Clozapine (C
相关文献及参考
- Merchant, K.M. et al.: J. Pharm. Exp. Ther., 279, 1392 (1996); Rubinstein, M. et al.: J. Neurosci., 21, 3756 (2001); Marona-Lewicka, D. et al.: Behav. Pharmacol., 20, 114 (2009);
- [1]. Mark H Corrigan, et al. Effectiveness of the selective D4 antagonist sonepiprazole in schizophrenia: a placebo-controlled trial. Biol Psychiatry. 2004 Mar 1;55(5):445-51.
