(S)-5-(Aminomethyl)-1-(5,7-Difluoro-1,2,3,4-Tetrahydronaphthalen-2-Yl)-1,3-Dihydro-2H-Imidazole-2-Thione Hydrochloride (S)-5-(氨甲基)-1-(5,7-二氟-1,2,3,4-四氢萘-2-基)-1,3-二氢-2H-咪唑-2-硫酮盐酸盐
CAS 170151-24-3 MFCD70151243
化学结构图
SMILES:
化学属性
| Mol. Formula | C14H16ClF2N3S |
|---|
别名和识别编码
| Chemical Name | (S)-5-(Aminomethyl)-1-(5,7-Difluoro-1,2,3,4-Tetrahydronaphthalen-2-Yl)-1,3-Dihydro-2H-Imidazole-2-Thione Hydrochloride |
|---|---|
| Chemical Name Translation | (S)-5-(氨甲基)-1-(5,7-二氟-1,2,3,4-四氢萘-2-基)-1,3-二氢-2H-咪唑-2-硫酮盐酸盐 |
| Chemicalbook ID | CB22611129 |
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相关文献及参考
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- [3]. Stanley WC, et al. Catecholamine modulatory effects of nepicastat (RS-25560-197), a novel, potent and selective inhibitor of dopamine-beta-hydroxylase. Br J Pharmacol. 1997 Aug;121(8):1803-9.
- [4]. Sabbah HN, et al. Effects of dopamine beta-hydroxylase inhibition with nepicastat on the progression of left ventricular dysfunction and remodeling in dogs with chronic heart failure.
- [1]. Beliaev A, et al. Synthesis and biological evaluation of novel, peripherally selective chromanyl imidazolethione-based inhibitors of dopamine beta-hydroxylase.J Med Chem. 2006 Feb 9;49(3):1191-7.
- [1]. Beliaev A, et al. Synthesis and biological evaluation of novel, peripherally selective chromanyl imidazolethione-based inhibitors of dopamine beta-hydroxylase.J Med Chem. 2006 Feb 9;49(3):1191-7.
