Nalfurafine Hydrochloride 盐酸纳呋拉啡

CAS 152658-17-8 MFCD52658178

化学结构图

152658-17-8
SMILES: CN([C@@H]1CC[C@@]2(O)[C@H]3CC4C=CC(O)=C5O[C@@H]1[C@]2(CCN3CC1CC1)C=45)C(=O)/C=C/C1=COC=C1

化学属性

Mol. Weight513.03
Mol. FormulaC28H33ClN2O5

别名和识别编码

CAS Number152658-17-8
Chemical NameNalfurafine Hydrochloride
Synonym ########
Chemical Name Translation盐酸纳呋拉啡
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分类

  • Agonists
  • Chiral Reagents
  • Heterocycles
  • Neurochemicals
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

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相关文献及参考

  • [2]. Endoh T, et al. Potent antinociceptive effects of TRK-820, a novel kappa-opioid receptor agonist.Life Sci. 1999;65(16):1685-94.
  • Fujii, H., et al.: Bioorg. Med. Chem., 12, 4133 (2004),
  • Fujii, H., et al.: Curr. Med. Chem., 13, 1109 (2006),
  • Mori, T., et al.: Life Sci., 75, 2433 (2004),
  • [1]. Kaski SW, et al. Preclinical Testing of Nalfurafine as an Opioid-sparing Adjuvant that Potentiates Analgesia by the Mu Opioid Receptor-targeting Agonist Morphine.J Pharmacol Exp Ther. 2019 Nov;371(2):487-499.
  • [1]. Kaski SW, et al. Preclinical Testing of Nalfurafine as an Opioid-sparing Adjuvant that Potentiates Analgesia by the Mu Opioid Receptor-targeting Agonist Morphine.J Pharmacol Exp Ther. 2019 Nov;371(2):487-499.
  • [2]. Endoh T, et al. Potent antinociceptive effects of TRK-820, a novel kappa-opioid receptor agonist.Life Sci. 1999;65(16):1685-94.

系列性分类


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