Ganirelix Acetate Ganirelix醋酸盐

CAS 129311-55-3 MFCD29311553

化学结构图

129311-55-3
SMILES:

化学属性

Mol. Weight1570
Mol. FormulaC80H113ClN18O13

别名和识别编码

CAS Number129311-55-3
Chemical NameGanirelix Acetate
Synonym Antagon Antagon N-Acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N6-[bis(ethylamino)methylene]-D-lysyl-L-leucyl-N6-[bis(ethylamino)methylene]-L-lysyl-L-prolyl-D-alaninamide diacetate Orgalutran N-Acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N6-[bis(ethylamino)methylene]-D-lysyl-L-leucyl-N6-[bis(ethylamino)methylene]-L-lysyl-L-prolyl- N-Acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N6-[bis(ethylamino)methylene]-D-lysyl-L-leucyl-N6-[bis(ethylamino)methylene]-L-lysyl-L-prolyl-D-alaninamide diacetate Orgalutran
Chemical Name TranslationGanirelix醋酸盐
MDL Number
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分类

  • {SNA} Bioactive Small Molecule Alphabetical Index, Cytokines, Growth Factors and Hormones, G, Hormones, Luteinizing Hormone (LH), Pituitary Hormones, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
  • Cell Biology, Cell Signaling and Neuroscience, Cytokines, Growth Factors and Hormones,

产品应用

  • Decapeptide LH-RH antagonist. Used in treatment of infertility.

相关文献及参考

  • Strickley, R.G., et al.: Pharm. Res., 7, 530 (1990),
  • Jung, G., et al.: J. Med. Chem., 35, 3942 (1992),
  • Rabinovici, J., et al.: J. Clin. Endocrinol. Metab., 75, 1220 (1992),
  • Banga, F.R., et al., Pituitary sensitizing effect of GnRH antagonists: a mechanism explaining LH escape during IVF? Hum. Reprod. 25 , 1513-1519, (2010)
  • Martinez-Salazar, J., et al., GnRH antagonist ganirelix prevents premature luteinization in IUI cycles: rationale for its use. Reprod. Biomed. Online 19 , 156-161, (2009)

安全信息

GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Signal word Warning
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
WGK Germany3
Hazard Codes Xi
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Cytokines, Growth Factors and Hormones - Cell Signaling and Neuroscience
  5. Hormones - Cytokines, Growth Factors and Hormones
  6. Pituitary Hormones - Hormones
  7. Luteinizing Hormone (LH) - Pituitary Hormones

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