CGP-42112A CGP-42112游离态
CAS 127060-75-7 MFCD27060757
化学结构图
SMILES: C[C@@H](CC)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC1=CNC=N1)NC(=O)[C@H](CCCCNC(=O)[C@H](CCCNC(N)=N)NC(=O)OCC1C=CC=CC=1)NC(=O)[C@H](CC1C=CC(O)=CC=1)NC(=O)C1C=NC=CC=1)C(O)=O
化学属性
| Mol. Weight | 1052.18 |
|---|---|
| Mol. Formula | C52H69N13O11 |
别名和识别编码
| Synonym | Nα-Nicotinoyl-Tyr-(Nα-Cbz-Arg)-Lys-His-Pro-Ile |
|---|---|
| Chemical Name | CGP-42112 |
| MDL Number | MFCD00133611 |
| PubChem Substance ID | 24892424 |
| Beilstein Registry Number | 8184948 |
| Chemical Name Translation | CGP-42112游离态 |
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分类
- {SNA} Angiotensin Receptor Agonists, Angiotensins, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Membrane Protein Biology Tools, Neuropeptides, Peptides and Proteins, Peptides for Cell Biology, 生化试剂, 细胞信号转导和神经科学, 细胞生物学, 蛋白质及衍生物
相关文献及参考
- [2]. Speth RC. [125I]CGP 42112 binding reveals differences between rat brain and adrenal AT2 receptor binding sites. Regul Pept. 1993 Mar 19;44(2):189-97.
- [3]. Naveri L, et al. Angiotensin II AT2 receptor stimulation extends the upper limit of cerebral blood flow autoregulation: agonist effects of CGP 42112 and PD 123319. J Cereb Blood Flow Metab. 1994 Jan;14(1):38-44.
- [4]. Heemskerk FM, et al. Quantitative autoradiography of angiotensin II AT2 receptors with [125I]CGP 42112. Brain Res. 1995 Apr 17;677(1):29-38.
- [1]. Takekoshi K, et al. Angiotensin-II subtype 2 receptor agonist (CGP-42112) inhibits catecholamine biosynthesis in cultured porcine adrenal medullary chromaffin cells. Biochem Biophys Res Commun. 2000 Jun 7;272
- [1]. Takekoshi K, et al. Angiotensin-II subtype 2 receptor agonist (CGP-42112) inhibits catecholamine biosynthesis in cultured porcine adrenal medullary chromaffin cells. Biochem Biophys Res Commun. 2000 Jun 7;272(2):544-50.
