Candoxatril
CAS 123122-55-4 MFCD23122554
化学结构图
SMILES: COCCOC[C@@H](CC1(CCCC1)C(=O)N[C@H]1CC[C@H](CC1)C(O)=O)C(=O)OC1C=C2CCCC2=CC=1 |&1:6,16,19|
化学属性
| Mol. Weight | 515.64 |
|---|---|
| Mol. Formula | C29H41NO7 |
别名和识别编码
| CAS Number | 123122-55-4 |
|---|---|
| Chemical Name | Candoxatril |
| Synonym | cis-4-[[[1-[(2S)-3-[(2,3-Dihydro-1H-inden-5-yl)oxy]-2-[(2-methoxyethoxy)methyl]-3-oxopropyl]cyclopentyl]carbonyl]amino]cyclohexanecarboxylic Acid UK 79300 |
| Chemical Name Translation |
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信息真实价格透明
资金保障
专业采购外包团队在线服务
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现货库存
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分类
- Aromatics
- Chiral Reagents
- Inhibitors
- Pharmaceuticals
- Intermediates & Fine Chemicals
产品应用
- Neutral endopeptidase inhibitor. Used in treatment of congestive heart failure.
相关文献及参考
- [2]. M Aleksinskaya, et al. Neutral endopeptidase inhibitors SOL-1 and candoxatril counteract kidney fibrosis by reducing myofibroblast formation in mouse UUO model. Bmc Pharmacology & Toxicology , 2013 , 14 (1) :1-2.
- Kimmelstiel, C.D., et al.: Cardiology, 87, 46 (1996),
- Motwani, J.G., et al.: Clin. Pharmacol. Ther., 54, 661 (1993),
- [1]. Bevan EG, et al. Candoxatril, a neutral endopeptidase inhibitor: efficacy and tolerability in essential hypertension. J Hypertens. 1992 Jul;10(7):607-13.
- [1]. Bevan EG, et al. Candoxatril, a neutral endopeptidase inhibitor: efficacy and tolerability in essential hypertension. J Hypertens. 1992 Jul;10(7):607-13.
- [2]. M Aleksinskaya, et al. Neutral endopeptidase inhibitors SOL-1 and candoxatril counteract kidney fibrosis by reducing myofibroblast formation in mouse UUO model. Bmc Pharmacology & Toxicology , 2013 , 14 (1) :1-2.
