CAS 96-18-4 MFCD00000946-1,2,3-Trichloropropane 1,2,3-三氯丙烷 TAO{mole}

1,2,3-Trichloropropane 1,2,3-三氯丙烷

CAS 96-18-4 MFCD00000946

化学结构图

SMILES: ClCC(Cl)CCl

化学属性

Mol. Formula	C3H5Cl3
Mol. Weight	147
Refractive index	1.4820 to 1.4860
Density	1.387
Flash Point	73°C(lit.)
TSCA	Yes
Boiling Point	156
Melting Point	-14
Solubility	2 G/L (25 ºC)

别名和识别编码

Chemical Name	1,2,3-Trichloropropane
CAS Number	96-18-4
EC Number	202-486-1
Synonym	1,2,3-TRICHLOROPROPANE 1,2,3-TRICHLOROPROPANE, 1000MG, NEAT 1,2,3-TRICHLOROPROPANE, 1X1ML, MEOH, 200 UG/ML 1,2,3-TRICHLOROPROPANE, 1X1ML, MEOH, 500 0UG/ML 1,2,3-TRICHLOROPROPANE, not stabilized, OEKANAL 1,2,3-Trichlorpropan 1,2,3-trichloro-propan 1,2,3-trichloro-propane 1,2,3-trichloropropane 1,2,3-三氯丙烷 1,2,3-三氯丙烷, 98+% 1,2,3-二氯丙烷 1，2，3-三氯丙烷 Glycerintrichlorhydrin Glycerol trichlorohydrin Glycerol trichlorohydrinTrichlorohydrin Glyceryl trichlorohydrin NCI-C60220 TRICHLOROHYDRIN TRICHLOROPROPANE Trichlorohydrin 三氯丙烷 Trichlorohydrin, Glycerol trichlorohydrin allyltrichloride glyceryltrichlorohydrin propane, 1,2,3-trichloro- {} {ALD {} {} {} {} {uni
MDL Number	MFCD00000946
Reaxys-RN	1732068
Beilstein Registry Number	1732068
PubChem Substance ID	7285
Chemical Name Translation	1,2,3-三氯丙烷
Wiswesser Line Notation	G1YG1G
LabNetwork Molecule ID	LN00224857
InChI	InChI=1S/C3H5Cl3/c4-1-3(6)2-5/h3H,1-2H2

信息真实价格透明资金保障专业采购外包团队在线服务

品牌质保精细包装现货库存一流品牌服务

安全信息

Hazard statements

H332 Harmful if inhaled 吸入有害
H350 May cause cancer 可能致癌
H302 Harmful if swallowed 吞食有害
H312 Harmful in contact with skin 皮肤接触有害
H360 May damage fertility or the unborn child 可能对生育能力或未出生婴儿造成伤害
H302+H312+H332
H341 Suspected of causing genetic defects 怀疑导致遗传性缺陷
H319 Causes serious eye irritation 严重刺激眼睛
H301+H311+H331
H372 Causes damage to organs through prolonged or repeated exposure 长期或频繁接触会损伤器官
H373 May causes damage to organs through prolonged or repeated exposure 长期或频繁接触可能会损伤器官
H411 Toxictoaquaticlifewithlonglastingeffects 对水生生物有毒性并具有长期影响。
H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
H227 Combustible liquid 可燃液体

Hazard Codes 6.1 F,T T T,F T,N

GHS Symbol

Precautionary statements

P201 Obtain special instructions before use. 使用前获取专门指示。
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P301+P310
P301+P310+P330
P302+P350
P302+P352+P312+P361+P364
P304+P340+P310
P308+P313
P330 Rinse mouth. 漱口
P337+P313
P403+P233
P501 Dispose of contents/container to..… 处理内容物/容器.....

WGK Germany3

Signal word Danger

Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

RTECSTZ9275000

UN Number 2810 UN2810

Storage condition -20°C 0-10 储存温度2-8℃ 0-10°C

Risk Statements

R20 Harmful by inhalation 吸入有害
R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
R24/25 Toxic in contact with skin and if swallowed 皮肤接触及吞食都有毒
R36 Irritating to eyes 刺激眼睛
R45 May cause cancer 可能致癌
R48/21/22
R48/23
R60 May impair fertility 可能降低生殖能力
R68/20/21/22

Safety Statements

S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
S53 Avoid exposure - obtain special instructions before use 避免接触，使用前获得特别指示说明；
S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中，参考特别指示/安全收据说明书；

Packing GroupIII

Hazard Class6.1

Warnings 危化品目录(2015) 危险化学品

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 5200 mg/kg/2Y-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Gastrointestinal - tumors
   Skin and Appendages - tumors
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-384,1993

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3120 mg/kg/2Y-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Gastrointestinal - tumors
   Liver - tumors
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-384,1993

TYPE OF TEST            : LD50 - Let

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 340 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - ataxia
   Blood - other changes
REFERENCE :
   TKGMB8 Trudy Khar'kovskogo Meditsinskogo Instituta.  (Khar'kovskii
   Gosudarstvennyi Meditsinskii Institut, Kharkov, USSR) N.1- 1935-
   Volume(issue)/page/year: 124,27,1976

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Behavioral - sleep
   Liver - hepatitis (hepatocellular necrosis), zonal
   Liver - fatty liver degeneration
REFERENCE :
   AJHYA2 American Journal of Hygiene.  (Baltimore, MD)  V.1-80, 1921-64.  For
   publisher information, see AJEPAS.  Volume(issue)/page/year: 16,325,1932

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3400 mg/m3/2H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single
   Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects,
   GKNT, 1982  Volume(issue)/page/year: -,114,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 380 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - ataxia
   Blood - other changes
REFERENCE :
   TKGMB8 Trudy Khar'kovskogo Meditsinskogo Instituta.  (Khar'kovskii
   Gosudarstvennyi Meditsinskii Instit

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 500 ng/plate
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 7(Suppl
   3),15,1985

TYPE OF TEST            : DNA damage
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 55361 ug/kg
REFERENCE :
   CRTOEC Chemical Research in Toxicology.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB 57/36, West End Station, Washington, DC
   20037)  V.1-    1988-  Volume(issue)/page/year: 4,528,1991

TYPE OF TEST            : Cytogenetic analysis
ROUTE OF EXPOSURE       : Inhalation
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 800 ug/L
REFERENCE :
   BEXBAN Bulletin of Experimental Biology and Medicine (English Translation).
   Translation of BEBMAE. (Plenum Pub. Corp., 233 Spring St., New York, NY
   10013)  V.41-    1956-  Volume(issue)/page/year: 78,1414,1974

TYPE OF TEST            : DNA damage
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 2 mmol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 371,185,1996

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 300 umol/L
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 9,401,1987

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 400 mg/kg
SEX/DURATION            : male 5 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured
   before birth)
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 101,321,1982

其他信息

下游产品:丙烯酰氯 --> 2,3-二氯丙烯
可燃性危险特性:受热分解;燃烧时产生有毒氯化物气体;与氧化剂起作用
毒性与危险情况:(1) 三氯丙烷有毒，有腐蚀性及刺激性，也能被皮肤吸收而中毒，蒸气有麻醉性，其作用和三氯甲烷相似，但较慢; 对眼睛和呼吸道有强刺激作用。大鼠经口LD50320 mg/kg。 (2) 易燃，燃点580℉(304℃)。空气中三氯丙烷的最高容许浓度美国为50ppm (300mg/m3)。
刺激数据:皮肤-兔子 700 毫克轻度; 眼睛-兔子 140 毫克重度
运输要求:三氯丙烷属有机易燃有毒品。危规号： 84007。运输时容器上须标有“易燃有毒品”标记。
测定方法:在空气中三氯丙烷的测定：用活性炭吸附，CS2处理，气相色谱法分析。
Sigma Aldrich:96-18-4(sigmaaldrich)
爆炸物危险特性:与空气混合可爆
方法一:1.α-氯丙烯氯化法　丙烯高温氯化得烯丙基氯，经洗涤、分离后，再经低温氯化、分馏，即得成品。2.二氯异丙醇法。
用途一:用于生产农药和有机合成、气相色谱对比样品
MOL 文件:96-18-4.mol
类别:有毒物品
图谱信息:1,2,3-三氯丙烷(96-18-4)核磁图( 13 CNMR) 1,2,3-三氯丙烷(96-18-4)红外图谱(IR1) 1,2,3-三氯丙烷(96-18-4)Raman光谱 1,2,3-三氯丙烷(96-18-4)核磁图( 1 HNMR) 1,2,3-三氯丙烷(96-18-4)质谱(MS)
Alfa
海关编码:29031980
1,2,3-三氯丙烷价格(试剂级):更新日期产品编号产品名称包装价格 2011/08/23 xp400276 三氯丙烷 5ml 300元 2011/04/16 S0655 1,2,3-三氯丙烷(1mg/ml的甲醇溶液)[用于水分析] 1,2,3-Trichloropropane (1mg/ml in Methanol) [for Water Analysis] 1ML 198元 2011/04/16 T0395 1,2,3-三氯
职业标准:TWA 300 毫克/立方米; STEL 450 毫克/立方米
挥发性有机化合物(VOCs)单组分标准液
用途二:主要用以生产1,2,3-三氯丙烯，也是一种较好的溶剂。亦可作农药矮壮素和燕麦敌的原料。
贮存:用塑料桶或铁桶盛装，防止机械性损坏。存放于阴凉、通风、干燥处，远离火源。
灭火剂:雾状水、泡沫、二氧化碳，干粉。
上游原料:丙烯酰氯 --> 1,3-二氯丙醇
MSDS 信息:1,2,3-三氯丙烷(96-18-4).msds
{Che
TCI Shanghai:1,2,3-三氯丙烷(1mg/ml的甲醇溶液)[用于水分析] 1,2,3-Trichloropropane (1mg/ml in Methanol) [for
Acros Organics:1,2,3-三氯丙烷 1,2,3-Trichloropropane, 99+ %(96-18-4)
有机合成中间体:三氯丙烷是一种重要有机合成中间体，可用于制备甘油、三氯丙烯、丙炔醇、三乙酸甘油酯、四氯丙烯、2-氯丙胺、多氯丙烷、2，4-二甲基-3-乙酰基呋喃；三氯丙烷也是生产农药原料，可用于生产农药矮壮素和燕麦敌。三氯丙烷也是一种较好的溶剂，清除金属表面涂料及油漆，亦用作油脂、蜡、树脂及氯化橡胶的溶剂。三氯丙烷与碱金属多硫化物、双二氯乙烯基缩甲醛缩聚生成ST型聚硫橡胶。此外三氯丙烷还用作色谱分析标准物质。以上信息由Chemicalbook的彤彤编辑整理。
制备方法:(1) 从环氧氯丙烷生产中的高沸点混合物副产品中分离提取三氯丙烷。 (2) 以丙烯为原料进行氯化，可制得三氯丙烷。