PF 750
CAS 959151-50-9 MFCD10567109
化学结构图
SMILES: O=C(NC1C=CC=CC=1)N1CCC(CC2C=NC3=CC=CC=C3C=2)CC1
化学属性
| Mol. Formula | C22H23N3O |
|---|---|
| Mol. Weight | 345.44 |
别名和识别编码
| Chemical Name | PF-750 |
|---|---|
| CAS Number | 959151-50-9 |
| Synonym | N-Phenyl-4-(3-quinolinylmethyl)-1-piperidinecarboxamide N-Phenyl-4-(quinolin-3-ylmethyl)piperidine-1-carboxamide |
| MDL Number | MFCD10567109 |
| PubChem Substance ID | 329819993 |
| Chemical Name Translation |
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分类
- {SNA} Bioactive Small Molecule Alphabetical Index, Enzyme Inhibitors, Fatty Acid Amide Hydrolase, Neuroscience, Neurotransmission, Neurotransmitter Metabolism, P-PH, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
- Inhibitors
- Heterocycles
- Pharmaceuticals
- Pfizer Compounds
- Amines
- {SA} Cell Biology, Cell Signaling and Neuroscience,
产品应用
- Fatty acid amide hydrolase (FAAH) inhibitor, selectively inhibiting FAAH within the central nervous system
相关文献及参考
- Ahn, K., et al.: Biochem., 46, 13019 (2007),
- LinksAhn K, et al., Novel mechanistic class of fatty acid amide hydrolase inhibitors with remarkable selectivity. Biochemistry 46 , 13019-30, (2007) 摘要
- Mileni M., et al., Structure-guided inhibitor design for human FAAH by interspecies active site conversion. Proc. Natl. Acad. Sci. U. S. A. 105 , 12820-4, (2008) 摘要
- Mileni, M., et al.: Proc. Natl. Acad. Sci. USA., 105, 12820 (2008),
安全信息
GHS Symbol
- H302 Harmful if swallowed 吞食有害
- R22 Harmful if swallowed 吞咽有害
