4-(4-Pyrazolyl)-7-[[2-(Trimethylsilyl)Ethoxy]Methyl]-7H-Pyrrolo[2,3-D]Pyrimidine 4-(4-吡唑基)-7-[[2-(三甲基硅基)乙氧基]甲基]-7H-吡咯并[2,3-d]嘧啶

CAS 941685-27-4 MFCD11857754

化学结构图

941685-27-4
SMILES: C[Si](C)(C)CCOCN1C=CC2C1=NC=NC=2C1C=NNC=1

化学属性

Mol. FormulaC15H21N5OSi
Mol. Weight315.45

别名和识别编码

Chemical Name4-(4-Pyrazolyl)-7-[[2-(Trimethylsilyl)Ethoxy]Methyl]-7H-Pyrrolo[2,3-D]Pyrimidine
Alfabeta NamePYRAZOLYLTRIMETHYLSILYLETHOXYMETHYLPYRROLOPYRIMIDINE HHD41472723[](((())))-----------,
MDL NumberMFCD11857754
CAS Number941685-27-4
Synonym 4-(1H-Pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine INCB032304
PubChem Substance ID329772298
Chemical Name Translation4-(4-吡唑基)-7-[[2-(三甲基硅基)乙氧基]甲基]-7H-吡咯并[2,3-d]嘧啶
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分类

  • {SNA} Building Blocks, C10-C30+, C12 to C30+, C12 to C37, Chemical Synthesis, Halogenated Heterocycles, Heterocyclic Building Blocks, Organometallic Reagents, Organosilicon, Other Organosilicon, Pyrazoles, Pyrimidines
  • Heterocycles
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • {SNA} Building Blocks

产品应用

  • 4-(1H-Pyrazol-4-yl)-7-[[2-(trimethylsilyl)ethoxy]methyl]-7H-pyrrolo[2,3-d]pyrimidine is an important intermediate in the preparation of the janus kinase inhibitor INCB018424.

相关文献及参考

  • Lin, Q. et al.: Org. Lett., 11, 1999 (2009);

安全信息

Warnings IRRITANT
WGK Germany3
GHS Symbol
Signal word Warning
Hazard statements
  • H302 Harmful if swallowed 吞食有害
Hazard Codes Xn
Risk Statements
  • R22 Harmful if swallowed 吞咽有害

系列性分类


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