CAS 94-74-6 MFCD00004306-(4-Chloro-2-methylphenoxy)acetic Acid (4-氯-2-甲基苯氧基)乙酸 TAO{mole}

(4-Chloro-2-methylphenoxy)acetic Acid (4-氯-2-甲基苯氧基)乙酸

CAS 94-74-6 MFCD00004306

化学结构图

SMILES: Cc1cc(Cl)ccc1OCC(=O)O

化学属性

Mol. Formula	C9H9ClO3
Mol. Weight	200.62
Melting Point	114-118°C
Density	1.313
Flash Point	2 °C
Solubility	难溶于水，易溶于多数有机溶剂。
Boiling Point	288.02 °C at 760 mmHg

别名和识别编码

Chemical Name	(4-Chloro-2-methylphenoxy)acetic Acid
CAS Number	94-74-6
Synonym	MCPA {LY} MCPA {} {LY} MCPA {} {} {LY} MCPA {} {} {} {LY} MCPA {} {} {} {} {LY} MCPA {} {} {} {} {} {LY} MCPA {} {} {} {} {} {} {LY} MCPA {} {} {} {} {} {} {} {LY} MCPA {} {} {} {} {} {} {} {} {LY} MCPA {} {} {} {} {} {} {} {} {} {LY} MCPA {} {} {} {} {} {} {} {} {} {} {LY} MCPA {} {} {} {} {} {} {} {} {} {} {} {LY} MCPA {} {} {} {} {} {} {} {} {} {} {} {} {LY} MCPA {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} MCPA {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} MCPA {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} MCPA {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} MCPA {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} MCPA {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} MCPA {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} MCPA {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
Beilstein Registry Number	2051752
PubChem Substance ID	7204
EC Number	202-360-6
MDL Number	MFCD00004306
Reaxys-RN	2051752
Merck Number	5764
Chemical Name Translation	(4-氯-2-甲基苯氧基)乙酸
Wiswesser Line Notation	QV1OR DG B1
InChI	InChI=1S/C9H9ClO3/c1-6-4-7(10)2-3-8(6)13-5-9(11)12/h2-4H,5H2,1H3,(H,11,12)
Canonical SMILES	O=C(O)COC1=CC=C(Cl)C=C1C

信息真实价格透明资金保障专业采购外包团队在线服务

品牌质保精细包装现货库存一流品牌服务

产品应用

激素型除草剂

安全信息

Precautionary statements

P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P332+P313
P501 Dispose of contents/container to..… 处理内容物/容器.....
P301+P312+P330
P302+P350
P302+P352+P332+P313+P362+P364
P305+P351+P338+P310

GHS Symbol

Signal word Danger

Hazard statements

H315 Causes skin irritation 会刺激皮肤
H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
H318 Causes serious eye damage 严重伤害眼睛
H302 Harmful if swallowed 吞食有害
H302+H332
H332 Harmful if inhaled 吸入有害
H319 Causes serious eye irritation 严重刺激眼睛
H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
H312 Harmful in contact with skin 皮肤接触有害

Hazard Codes F,Xn Xn,F Xn Xn,N

WGK Germany3

RTECSAG1575000

Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter dust mask type N95 (US), Eyeshields, Gloves

Safety Statements

S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；
S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中，参考特别指示/安全收据说明书；
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
S37 Wear suitable gloves 戴适当手套；
S39 Wear eye/face protection 戴眼睛/面孔保护装置；
S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
S16 Keep away from sources of ignition - No smoking 远离火源，禁止吸烟；
S36 Wear suitable protective clothing 穿戴适当的防护服；

Risk Statements

R11 Highly flammable 非常易燃
R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
R38 Irritating to skin 刺激皮肤
R36 Irritating to eyes 刺激眼睛
R22 Harmful if swallowed 吞咽有害
R50/53

UN Number 2765 UN 2765

Storage condition 2-8°C, protect from light {LY} 2-8°C, protect from light APPROX 4°C {} {LY} 2-8°C, protect from light {} {} {LY} 2-8°C, protect from light {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Bird - quail
DOSE/DURATION           : 377 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FMCHA2 Farm Chemicals Handbook.  (Meister Pub., 37841 Euclid Ave.,
   Willoughy, OH 44094)  Volume(issue)/page/year: -,C191,1991

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   WRPCA2 World Review of Pest Control.  (London, UK)  V.1-10, 1962-71.
   Discontinued.  Volume(issue)/page/year: 9,119,1970

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : >2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology,
   Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128)  V.1-
   1990-  Volume(issue)/page/year: 1,86,1990

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1370 mg/m3/4H
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology,
   Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128)  V.1-
   1990-  Volume(issue)/page/year: 1,86,1

TYPE OF TEST            : LD50 - Lethal dos

TYPE OF TEST            : DNA inhibition
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 55,197,1978

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 10 umol/L/1H
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 5,703,1984

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 250 ug/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 204,615,1988

TYPE OF TEST            : Gene conversion and mitotic recombination
TEST SYSTEM             : Mold - Aspergillus nidulans
DOSE/DURATION           : 1500 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 204,615,1988

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
DOSE/DURATION           : 30 umol/L/3H
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 60,291,1979

TYPE OF TEST            : Sister chromatid exchange
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - hamster
DOSE/DURATION           : 900 mg/kg/9D (Intermittent)
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfie

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 3 gm/kg
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 33,1479,1983

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 1 gm/kg
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 33,1479,1983

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 2 gm/kg
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - craniofacial
   (including nose and tongue)
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 33,1479,1983

其他信息

用途三:该品商品为2-甲-4-氯钠盐，
方法二:由邻甲酚经缩合、酸化、氯化而得。将26.24kg邻甲酚、13.9kg水、35%的氢氧化钠溶液27.37kg投入缩合锅内，在70℃以下搅拌配合成邻甲酚钠盐。在21.88kg氯乙酸和41.66kg水中，在25℃以下慢慢加入35%的氢氧化钠溶液26.56kg，使pH值为5-6，在60℃条件下酸化20min。将反应物在脱酚槽内加热至90-95℃，通过热蒸气脱酚。然后在pH值为1-2、60-65℃条件下氯化。再经冷却、过滤、水洗即得2-甲-4-氯。原药2-甲-4-氯钠原药为深褐色粉末，按HG 2-1460-82，有效成分含量≥56.0%。原料消耗定额：邻甲酚730kg/t、液氯600kg/t、氯
方法一:2甲4氯的生产方法可概括为先缩合后氯化和先氯化后缩合2种。两种方法各有优缺点，先缩合后氯化生产原理如下。缩合于100～105℃ 反应1h，缩合反应即完成。酸化用盐酸调节pH值至5左右，于90～95℃进行脱酚处理。氯化加盐酸调节pH值1～2，于60
TCI Shanghai:(4-氯-2-甲基苯氧基)乙酸 (4-Chloro-2-methylphenoxy)acetic Acid,>;98.0%(T)(94-74-6)
毒性分级:中毒
方法一:2甲4氯的生产方法可概括为先缩合后氯化和先氯化后缩合2种。两种方法各有优缺点，先缩合后氯化生产原理如下。缩合于100～105℃ 反应1h，缩合反应即完成。
急性毒性:口服- 大鼠 LD50: 700 毫克/公斤; 口服- 小鼠 LD50: 439 毫克/公斤
用途二:激素型选择性除草剂，易为根部和叶部吸收传导。用于水稻等禾本科作物田间，芽后防除多种一年生或多年生阔叶杂草和某些单子叶杂草。对杀灭阔叶草及三梭草有特效，但对稗草类杂草无效。使用剂量为0.28～2.25kg有效成分/hm 2 。对棉花、黄豆、瓜菜等阔叶作物有影响。
方法二:由邻甲酚经缩合、酸化、氯化而得。将26.24kg邻甲酚、13.9kg水、35%的氢氧化钠溶液27.37kg投入缩合锅内，在70℃以下搅拌配合成邻甲酚钠盐。在21.88kg氯乙酸和41.66kg水中，在25℃以下慢慢加入35%的氢
用途四:该品商品为2-甲-4-氯钠盐，加工成20%水剂。为激素型除草剂，易为根和叶部吸收和传导，破坏植物的新陈代谢，致使植物变型；肿裂霉烂而死亡。适用于消灭禾木科作物，如小粒谷物、水稻、豌豆、草坪中的杂草，防除多种一年生和多年生双子叶宽叶杂草和某些单子叶杂草，使用剂量为0.28-2.25kg(有效成分)/hm2。对杀出阔叶草及三凌草等也有特效。该品对棉花、黄豆、瓜菜等阔叶作物影响很大，喷药后会死亡。该品不能与酸性能要混用。
储运特性:库房通风低温干燥; 与食品原料分开储运
外观性质:无色无味结晶。
用途三:该品商品为2-甲-4-氯钠盐，加工成20%水剂。为激素型除草剂，易为根和叶部吸收和传导，破坏植物的新陈代谢，致使植物变型、肿裂霉烂而死亡。适用于消灭禾木科作物，如小粒谷物、水稻、豌豆、草坪中的杂草，防除多种一年生和多年生双子叶宽叶杂草和某些
MOL 文件:94-74-6.mol
Sigma Aldrich:94-74-6(sigmaaldrich)
用途三:该品商品为2-甲-4-氯钠盐，加工成20%水剂。为激素型除草剂，易为根和叶部吸收和传导，破坏植物的新陈代谢
2-甲基-4-氯苯氧乙酸价格(试剂级):更新日期产品编号产品名称包装价格 2014/06/02 C0206 (4-氯-2-甲基苯氧基)乙酸 (4-Chloro-2-methylphenoxy)acetic Acid 500G 1100元 2014/06/02 C0206 (4-氯-2-甲基苯氧基)乙酸 (4-Chloro-2-methylphenoxy)acetic Acid 25G 98元
溶于有机溶剂，在水中溶解度为825ppm。
方法一:2甲4氯的生产方法可概括为先缩合后氯化和先氯化后缩合