CAS 92-39-7 MFCD00005016-2-Chlorophenothiazine 2-氯吩噻嗪 TAO{mole}

2-Chlorophenothiazine 2-氯吩噻嗪

CAS 92-39-7 MFCD00005016

化学结构图

SMILES: Clc1ccc2c(c1)Nc1ccccc1S2

化学属性

Mol. Formula	C12H8ClNS
Mol. Weight	233.72
Melting Point	195-200°C
TSCA	Yes
Density	1.346
Appearance	浅黄色或银灰色结晶，熔点196-199℃（分解）。
Boiling Point	395.7±31.0 °C at 760 mmHg

别名和识别编码

Chemical Name	2-Chlorophenothiazine
CAS Number	92-39-7
Synonym	2-Chlorophenothiazine {LY} 2-Chlorophenothiazine {} {LY} 2-Chlorophenothiazine {} {} {LY} 2-Chlorophenothiazine {} {} {} {LY} 2-Chlorophenothiazine {} {} {} {} {LY} 2-Chlorophenothiazine {} {} {} {} {} {LY} 2-Chlorophenothiazine {} {} {} {} {} {} {LY} 2-Chlorophenothiazine {} {} {} {} {} {} {} {LY} 2-Chlorophenothiazine {} {} {} {} {} {} {} {} {LY} 2-Chlorophenothiazine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Chlorophenothiazine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Chlorophenothiazine {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Chlorophenothiazine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Chlorophenothiazine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Chlorophenothiazine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Chlorophenothiazine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Chlo
MDL Number	MFCD00005016
PubChem Substance ID	87565408
Beilstein Registry Number	176587
EC Number	202-152-5
Reaxys-RN	176587
Alfabeta Name	CHLOROPHENOTHIAZINE H210---
Chemical Name Translation	2-氯吩噻嗪
Wiswesser Line Notation	T C666 BM ISJ EG
LabNetwork Molecule ID	LN00179331
Canonical SMILES	ClC(C=C1N2)=CC=C1SC3=C2C=CC=C3

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品牌质保精细包装现货库存一流品牌服务

产品应用

Metabolite of Chloropromazine

安全信息

WGK Germany3

GHS Symbol

Precautionary statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P302+P350
P302+P352+P332+P313+P362+P364
P305+P351+P338
P305+P351+P338+P337+P313
P332+P313
P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用

Hazard statements

H315 Causes skin irritation 会刺激皮肤
H319 Causes serious eye irritation 严重刺激眼睛
H335 May cause respiratory irritation 可能导致呼吸道刺激

Hazard Codes Xi

RTECSSN7580000

Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves

Signal word Warning

Safety Statements

S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
S36 Wear suitable protective clothing 穿戴适当的防护服；

Risk Statements

R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

Warnings IRRITANT

Storage condition Store at room temperature {LY} Store at room temperature {} {LY} Store at room temperature {} {} {LY} Store at room temperature {} {} {} {LY} Store at room temperature {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}

UN Number UN 2811 6.1/PG 3

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 18 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
   Laboratory, NIOSH Exchange Chemicals.  (Aberdeen Proving Ground, MD 21010)
   Volume(issue)/page/year: NX#00590

TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 160 mg/L
REFERENCE :
   BCPCA6 Biochemical Pharmacology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.1-    1958-  Volume(issue)/page/year:
   26,1205,1977

TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 160 mg/L
REFERENCE :
   BCPCA6 Biochemical Pharmacology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.1-    1958-  Volume(issue)/page/year:
   26,1205,1977

其他信息

方法一:由间氯二苯胺经环合而得。在反应锅内加入间氯二苯胺和硫磺，升温至70℃，加入碘。升温至120℃，减压排出硫化氢，再升温至168-172℃，保温0.5h。冷却，加入氯苯和活性炭，加热回流1h。趁热过滤，滤液冷至15℃结晶。甩滤，用氯苯、乙醇洗涤滤饼各1次，得2-氯吩噻嗪。
类别:有毒物质
灭火剂:水, 二氧化碳, 干粉, 砂土
毒性分级:高毒
用途二:医药中间体，用于制备氯丙嗪、奋乃静。
2-氯吩噻嗪价格(试剂级):更新日期产品编号产品名称包装价格 2014/06/02 C0248 2-氯吩噻嗪 2-Chlorophenothiazine 500G 3010元 2014/06/02 C0248 2-氯吩噻嗪 2-Chlorophenothiazine 25G 352元 2010/06/21 334550250 2-氯吩噻嗪 2-Chlorophenothiazine 99% 25 GR 386元
MSDS 信息:2-Chlorophenothiazine(92-39-7).msds
下游产品:盐酸氯丙嗪 --> 奋乃静
Acros Organics:2-氯吩噻嗪 2-Chlorophenothiazine, 99%(92-39-7)
急性毒性:静脉- 小鼠 LD50: 18 毫克/公斤
上游原料:氢硫酸 --> 间氯二苯胺
Sigma Aldrich:92-39-7(sigmaaldrich)
储运特性:库房低温, 通风, 干燥; 与食品原料分开存放
用途一:用作药物盐酸氯丙嗪的中间体
TCI Shanghai:2-氯吩噻嗪 2-Chlorophenothiazine,>;98.0%(GC)(92-39-7)
图谱信息:2-氯吩噻嗪(92-39-7)红外图谱(IR1) 2-氯吩噻嗪(92-39-7)质谱(MS) 2-氯吩噻嗪(92-39-7)核磁图( 13 CNMR) 2-氯吩噻嗪(92-39-7)红外图谱(IR2)
可燃性危险特性:可燃, 燃烧时分解有毒氯化物, 硫氧化物和氮氧化物气体
MOL 文件:92-39-7.mol
Alfa Aesar:2-氯吩噻嗪,99% 2-Chlorophenothiazine, 99%(92-39-7)