CAS 915-67-3 MFCD00004076-Amaranth 苋菜红 TAO{mole}

Amaranth 苋菜红

CAS 915-67-3 MFCD00004076

化学结构图

SMILES: O=S(=O)([O-])c1ccc2c(/N=N/c3ccc(S(=O)(=O)[O-])c4ccccc34)c(O)c(S(=O)(=O)[O-])cc2c1.[Na+].[Na+].[Na+]

化学属性

Mol. Formula	C20H11N2Na3O10S3
Mol. Weight	604
Melting Point	218-220°C
Density	1.5
Solubility	50 G/L (20 ºC)
Stability	对光敏感

别名和识别编码

Chemical Name	Amaranth
Synonym	1-(4-磺酸-1-萘偶氮)-2-羟基-3,6-萘二磺酸三钠盐 ACID AMARANTH ACID RED 27 AZO RUBIN AZO RUBINE S Acid Red 27 Acilan Red SE Aizen Amaranth Amaranth S Specially Pure Bordeaux S Bordeaux S Extra Pure A C.I. Acid Red 27 C.I.酸性红27 CI 16185 Calcocid Amaranth Cerven potravinarska 9 C红2号 Dye FDC Red 2 EEC No. 123 FD & C Red Dye No. 2 FD AND C RED DYE NO 2 FD and C Red No FD&C; Red No. 2 FOOD RED NO 2 H HIDACID AMARANTH Hexacol Amaranth B Extra NAPHTHYLAMINE RED 萘酚酸性红27 食用苋菜红鸡冠花红
Beilstein Registry Number	4122311
MDL Number	MFCD00004076
CAS Number	915-67-3
EC Number	213-022-2
Reaxys-RN	4122311
PubChem Substance ID	13506
Merck Number	375
Chemical Name Translation	苋菜红
Wiswesser Line Notation	L66J BSWQ ENUN- BL66J CQ DSWQ HSWQ &-NA- 3
LabNetwork Molecule ID	LN01739920
InChI	InChI=1S/C20H14N2O10S3.3Na/c23-20-18(35(30,31)32)10-11-9-12(33(24,25)26)5-6-13(11)19(20)22-21-16-7-8-17(34(27,28)29)15-4-2-1-3-14(15)16;;;/h1-10,23H,(H,24,25,26)(H,27,28,29)(H,30,31,32);;;/q;3*+1/p-3

信息真实价格透明资金保障专业采购外包团队在线服务

品牌质保精细包装现货库存一流品牌服务

产品应用

生物染色剂。

安全信息

Hazard statements

H315 Causes skin irritation 会刺激皮肤
H319 Causes serious eye irritation 严重刺激眼睛
H335 May cause respiratory irritation 可能导致呼吸道刺激

GHS Symbol

RTECSQJ6550000

Precautionary statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P305+P351+P338

WGK Germany3

Signal word Warning

Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes Xi

Safety Statements

S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；

Risk Statements

R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

Storage condition 对光和热稳定性差，密封避光保存

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1200 gm/kg/78W-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Blood - lymphoma, including Hodgkin's disease
REFERENCE :
   GASTAB Gastroenterology.  (Academic Press, Inc., 1 E. First St., Duluth, MN
   55802)  V.1-    1943-  Volume(issue)/page/year: 23,1,1953

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1643 gm/kg/78W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Gastrointestinal - tumors
REFERENCE :
   NEZAAQ Nippon Eiseigaku Zasshi.  Japanese Journal of Hygiene.  (Nippon Eisei
   Gakkai, c/o Kyoto Daigaku Igakubu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606,
   Japan)  V.1-    1946-  Volume(issue)/page/year: 37,714,1982

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 680 gm/kg/14W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Gastrointestinal - tumors
   Blood - lymphoma, including Hodgkin's disease
REFERENCE :
   VPITAR Voprosy Pitaniya.  Problems of Nutrition.  (V/O Mezhdunarodnaya
   Kniga, 113095 Moscow, USSR) V.1-10, 1932-41; V.11-    1952-
   Volume(issue)/page/year: 29,61,1970

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 14,163,1976

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   SCPHA4 Scientia Pharmaceutica.  (Oesterreichische
   Apotheker-Verlagsgesellschaft MBH, Spitalgasse 31, 1094 Vienna 9, Austria)
   V.1-    1930-  Volume(issue)/page/year: 47,39,1979

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   SCPHA4 Scientia Pharmaceutica.  (Oesterreichische
   Apotheker-Verlagsgesellschaft MBH, Spitalgasse 31, 1094 Vienna 9, Austria)
   V.1-    1930-  Volume(issue)/page/year: 47,39,1979

TYPE OF TEST            : Gene conversion and mitotic recombination
TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
DOSE/DURATION           : 20 mg/L
REFERENCE :
   ENVIDV Environment International.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.1-    1978-  Volume(issue)/page/year:
   9,145,1983

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Fibroblast
DOSE/DURATION           : 1 gm/L/48H
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 48,337,1977

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 20 ug/L
REFERENCE :
   ENVIDV Environment International.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.1-    1978-  Volume(issue)/page/year:
   9,145,1983

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 20 ug/L
REFERENCE :
   ENVIDV Environment International.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.1-    1978-  Volume(issue)/page/year:
   9,145,1983

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 2 gm/L
REFERENCE :
   GMCRDC Gann Monograph on Cancer Research.  (Plenum Pub. Corp., 233 Spring
   St., New York, NY 10013) No. 11-    1971-  Volume(issue)/page/year:
   27,95,1981

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 296 mg/kg
SEX/DURATION            : multigenerations
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - viability index (e.g., # alive at day 4
   per # born alive)
   Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
   gain)
REFERENCE :
   TXCYAC Toxicology.  (Elsevier Scientific Pub. Ireland, Ltd., POB 85,
   Limerick, Ireland) V.1-    1973-  Volume(issue)/page/year

{h

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 250 mg/kg
SEX/DURATION            : male 1 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - male fertility index (e.g. # males impregnating
   females per # males exposed to fertile nonpregnant females)
   Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
   number of implants per female; total number of implants per corpora lutea)
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 14,163,1976

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 33 m

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - hamster
DOSE                    : 100 mg/kg
SEX/DURATION            : female 8 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   BECTA6 Bulletin of Environmental Contamination and Toxicology.
   (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way

其他信息

稳定性:Stable. Incompatible with strong oxidizing agents.
图谱信息:酸性红 27(915-67-3)红外图谱(IR2) 酸性红 27(915-67-3)红外图谱(IR1) 酸性红 27(915-67-3)核磁图( 1 HNMR)
毒害物质数据:915-67-3(Hazardous Substances Data)
含量分析:按OT-15中方法二测定。称取试样约3g(准确至0.0002g)溶于新煮沸并已冷却到室温的水中，移人500ml容量瓶中，稀释至刻度，摇匀。吸取50ml试样液置于250ml锥形瓶中，加入柠檬酸三钠15g，水150ml，在液面下通入二氧化碳气流的同时加热至沸，并用0.1mol/L三氯化钛标准液滴定至无色为终点。同时以50ml水代替试样液，以相同方法做一空白试验。
MOL 文件:915-67-3.mol
所属类别一:食品添加剂: 着色剂
RTECS号:QJ6550000
所属类别二:食品添加剂: 食用色素与护色剂: 食用色素(着色剂)
毒性:ADI 0～0.5mg/kg(FAO/WHO，2001)。LD 50 >10g/kg(小鼠，经口)。HACSG(欧共体儿童保护集团)不准用于儿童。挪威、美国、不准使用。
酸性红 27价格(试剂级):更新日期产品编号产品名称包装价格 2011/08/23 71003043 苋菜红;鸡冠花红;蓝光酸性红;对磺基萘偶氮-R-盐 10g 23.1元 2011/08/23 71003060 苋菜红;鸡冠花红;蓝光酸性红;对磺基萘偶氮-R-盐 10g 26.5元 2011/08/23 71003080 苋菜红;鸡冠花红;蓝光酸性红;对磺基萘偶氮-R-盐 10g 48元
使用限量:GB 2。760-2002(g/kg)：果汁(味)饮料类、碳酸饮料、配制酒、糖果、糕点上彩装、青梅、山楂制品，渍制小菜、威化饼干夹心、果冻、糖果包衣，均0.05；红绿丝、染色樱桃罐头(装饰用)，0.10；冰棍、冰激凌、雪糕，0.025。
EPA化学物质信息:2,7-Naphthalenedisulfonic acid, 3-hydroxy-4-[(4-sulfo-1-naphthalenyl) azo]-, trisodium salt(915-67-3)
易溶于水，水中溶解度:50 G/L (20°C)，呈带蓝光的红色溶液，可溶于甘油和丙二醇，微溶于乙醇，不溶于大多数有机溶剂。本品遇铜﹑铁易褪色，易被细菌分解，耐氧化﹑还原性差。
生产方法:由对氨基萘磺酸重氮化后与R酸(2-萘酚-3，6-二磺酸)偶合，经盐析、精制而得。
用途:作食品着色剂，我国规定可用于红绿丝、染色樱桃罐头(系装饰用)中，最大使用量为0.10g/kg；在各种饮料类、配制酒、糖果、糕点上彩装、青梅、山楂制品和浸渍小菜中，最大使用量0.05g/kg。
色指数:16185
参考质量标准:GB 4479.1-1999 苋菜红60 苋菜红85 含量/% ≥60.0 ≥85.0 水不溶物/% ≤0.30 ≤0.30 干燥减量、氯化物(以氯化钠计)及硫酸盐(以硫酸钠计)总量/% 一 ≤15 干燥减量/% ≤10.0 一副染料/% ≤3.0 ≤3.0 砷(As)/% ≤0.0001 ≤0.0001 重金属(以Pb计)/% ≤0.001 ≤0.001 GB 4479．2-1996(苋菜红铝色淀) 含量(以色酸计)/%@≥20.0 盐酸和氨不溶物/%@≤0.5 水溶性氯化物和硫酸盐/%@≤2.0 干燥失重(135℃，6h)/%@≤30.0 副染料/%@≤1.2 重金属(以Pb计)/%@≤0.002 砷(As)/%@≤0.0003 钡/%@≤0.05