PRL-3 Inhibitor 5-(5-溴-2-((2-溴苄基)氧基)苯亚甲基)-2-硫代噻唑烷-4-酮

CAS 893449-38-2 MFCD11045303

化学结构图

893449-38-2
SMILES: O=C1NC(=S)S/C/1=C/C1C=C(Br)C=CC=1OCC1=CC=CC=C1Br

化学属性

Mol. FormulaC17H11Br2NO2S2
Mol. Weight485.21

别名和识别编码

Chemical NamePRL-3 Inhibitor
Synonym 5-[[5-bromo-2-[(2-bromophenyl)methoxy]phenyl]methylene]-2-thioxo-4-thiazolidinone 5-[[5-bromo-2-[(2-bromophenyl)methoxy]phenyl]methylene]-2-thioxo-4-thiazolidinone Phosphatase of regenerating liver-3, Inhibitor I Phosphatase of regenerating liver-3, Inhibitor I
MDL NumberMFCD11045303
CAS Number893449-38-2
PubChem Substance ID329820016
Chemical Name Translation5-(5-溴-2-((2-溴苄基)氧基)苯亚甲基)-2-硫代噻唑烷-4-酮
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分类

  • {SNA} Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Kinase/Phosphatase Biology, P, Tyrosine Phosphatase (TP), Tyrosine Phosphatase Biology, Tyrosine Phosphatase Inhibitors
  • {SNA} Bioactive Small Molecule Alphabetical Index, Kinase/Phosphatase Biology, PI-PZ, Tyrosine Phosphatase (TP), Tyrosine Phosphatase Biology, Tyrosine Phosphatase Inhibitors, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
  • Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Kinase/Phosphatase Biology, P, Tyrosine Phosphatase (TP), Tyrosine Phosphatase Biology,

相关文献及参考

  • Ahn, J.H., et al., Synthesis and biological evaluation of rhodanine derivatives as PRL-3 inhibitors Bioorg. Med. Chem. Lett. 16 , 2996-2999, (2006) 摘要
  • [1]. Ahn JH, et al. Synthesis and biological evaluation of rhodanine derivatives as PRL-3 inhibitors. Bioorg Med Chem Lett. 2006;16(11):2996-2999.

安全信息

GHS Symbol
Precautionary statements
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Signal word Warning
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
WGK Germany3
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中，参考特别指示/安全收据说明书；
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
Hazard Codes Xi,N
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R50/53

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Kinase/Phosphatase Biology - Cell Signaling and Neuroscience
  5. Tyrosine Phosphatase Biology - Kinase/Phosphatase Biology
  6. Tyrosine Phosphatase Inhibitors - Tyrosine Phosphatase Biology
  7. Tyrosine Phosphatase (TP) - Tyrosine Phosphatase Inhibitors
  1. Medical Research Areas
  2. Metabolism
  3. Phosphatase  (磷酸酶)

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