RF9 TFA 2-金刚烷羰基-精氨酸-苯丙氨酸-NH2三氟乙酸酯
CAS 876310-60-0 MFCD09037400
化学结构图
SMILES: NC(=O)[C@H](CC1C=CC=CC=1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)C1[C@@H]2C[C@H]3C[C@H](C[C@@H]1C3)C2.OC(=O)C(F)(F)F
化学属性
| Mol. Formula | C26H38N6O3.C2HF3O2 |
|---|---|
| Mol. Weight | 596.647 |
别名和识别编码
| Chemical Name | RF9 TFA |
|---|---|
| Chemical Name Translation | 2-金刚烷羰基-精氨酸-苯丙氨酸-NH2三氟乙酸酯 |
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相关文献及参考
- [2]. Ting Zhang, et al. Discovery of Two Novel Branched Peptidomimetics Containing endomorphin-2 and RF9 Pharmacophores: Synthesis and Neuropharmacological Evaluation. Bioorg Med Chem. 2019 Feb 15;27(4):630-643.
- [1]. Simonin F, et al. RF9, a potent and selective neuropeptide FF receptor antagonist, prevents opioid-induced tolerance associated with hyperalgesia. Proc Natl Acad Sci U S A. 2006 Jan 10;103(2):466-71.
- [1]. Simonin F, et al. RF9, a potent and selective neuropeptide FF receptor antagonist, prevents opioid-induced tolerance associated with hyperalgesia. Proc Natl Acad Sci U S A. 2006 Jan 10;103(2):466-71.
- [2]. Ting Zhang, et al. Discovery of Two Novel Branched Peptidomimetics Containing endomorphin-2 and RF9 Pharmacophores: Synthesis and Neuropharmacological Evaluation. Bioorg Med Chem. 2019 Feb 15;27(4):630-643.
