Leptomycin B

CAS 87081-35-4 MFCD06795848

化学结构图

87081-35-4
SMILES: CC/C(=C/[C@H](C)C/C=C/C(/C)=C/[C@@H](C)C(=O)[C@@H](C)[C@H](O)[C@@H](C)C/C(/C)=C/C(O)=O)/C=C/[C@@H]1OC(=O)C=C[C@@H]1C

化学属性

Mol. FormulaC33H48O6
Mol. Weight541
Flash Point11°(52°F)
TSCANo

别名和识别编码

Chemical NameLeptomycin B solution from Streptomyces sp.
MDL NumberMFCD06795848
PubChem Substance ID24896330
Synonym Mantuamycin Elactocin Antibiotic CI 940 Antibiotic CL 1957A CL 1957A CI-940 PD 114720 Leptomycin B solution from Streptomyces sp.
CAS Number87081-35-4
Merck Number14,5444
Chemical Name Translation
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • {SNA} Antibiotics A to Z, Antibiotics G-M, Antifungal, Bioactive Small Molecule Alphabetical Index, Gene Regulation and Expression, L, Nuclear Translocation Regulators, Spectrum of Activity, 抗生素, 生化试剂, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
  • {SNA} Antibiotics, Antibiotics A to Z, Antibiotics G-M, Antifungal, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Gene Regulation and Expression, L, Nuclear Translocation Regulators, Spectrum of Activity

安全信息

WGK Germany1
GHS Symbol
Precautionary statements
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P310
  • P311 Call a POISON CENTER or doctor/physician. 呼叫解毒中心或医生/医师。
Hazard statements
  • H370 Causes damage to organs 导致器官损伤
  • H331 Toxic if inhaled 吸入中毒
  • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
  • H301 Toxic if swallowed 吞食有毒
  • H311 Toxic in contact with skin 皮肤接触中毒
Signal word Danger
Hazard Codes 3 F,T
Safety Statements
  • S16 Keep away from sources of ignition - No smoking 远离火源，禁止吸烟；
  • S24 Avoid contact with skin 避免皮肤接触；
  • S33 Take precautionary measures against static discharges 对静电采取预防措施；
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
  • S7 Keep container tightly closed 保存在严格密闭容器中；
Risk Statements
  • R23/25 Toxic by inhalation and if swallowed 吸入及吞食都有毒
  • R36/38 Irritating to eyes and skin 对眼睛和皮肤有刺激性
Packing GroupII
UN Number 1230
RTECSRA5390000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3100 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- ,  Berdy, J., Boca
   Raton, FL, CRC Press, 1980-  Volume(issue)/page/year: 13(3),204,1987

TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Rodent - mouse Leukocyte
DOSE/DURATION           : 1 umol/L
REFERENCE :
   PAACA3 Proceedings of the American Association for Cancer Research. (Waverly
   Press, 428 E. Preston St., Baltimore, MD 21202)  V.1-    1954-
   Volume(issue)/page/year: 26,253,1985

TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Rodent - mouse Leukocyte
DOSE/DURATION           : 1 umol/L
REFERENCE :
   PAACA3 Proceedings of the American Association for Cancer Research. (Waverly
   Press, 428 E. Preston St., Baltimore, MD 21202)  V.1-    1954-
   Volume(issue)/page/year: 26,253,1985

系列性分类

  1. Life Science 生命科学
  2. Antibiotics 抗生素
  3. Antibiotics A to Z - Antibiotics
  4. Antibiotics G-M - Antibiotics A to Z
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Gene Regulation and Expression - Cell Signaling and Neuroscience
  5. Nuclear Translocation Regulators - Gene Regulation and Expression

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