5-((2-Methylpiperazin-1-Yl)Sulfonyl)Isoquinoline 5-((2-甲基哌嗪-1-基)磺酰基)异喹啉
CAS 84477-87-2 MFCD00063403
化学结构图
SMILES: CC1CNCCN1S(=O)(=O)C1=CC=CC2=CN=CC=C21
化学属性
| Mol. Formula | C14H17N3O2S |
|---|---|
| Mol. Weight | 291.37 |
别名和识别编码
| Chemical Name | 5-((2-Methylpiperazin-1-Yl)Sulfonyl)Isoquinoline |
|---|---|
| Synonym | 1-(5-Isoquinolinesulfonyl)-2-methylpiperazine 1-(5-Isoquinolinesulfonyl)-2-methylpiperazine Isoquinoline-5-sulfonic 2-methyl-1-piperazide 1-(5-Isoquinolinylsulfonyl)-2-methylpiperazine H 7 H-7 Isoquinoline-5-sulfonic 2-methyl-1-piperazide |
| MDL Number | MFCD00063403 |
| PubChem Substance ID | 24896097 |
| Beilstein Registry Number | 5482740 |
| CAS Number | 84477-87-2 |
| Chemical Name Translation | 5-((2-甲基哌嗪-1-基)磺酰基)异喹啉 |
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分类
- Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, H, Kinase/Phosphatase Biology, P to Q, Protein Kinase Inhibitors, Protein kinase A, Protein kinase A and protein kinase C (PKA and PKC), Serine/Threonine Kinase Biology, Serine/Threonine Kinase Inhibitors
- {SNA} Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, H, Kinase/Phosphatase
相关文献及参考
- Qiu, L.B., et al., The Role Of Protein Kinase C In The Opening Of Blood-brain Barrier Induced By Electromagnetic Pulse. Toxicology 273 , 29-34, (2010) 摘要
- Hidaka, H., et al. Biochemistry 23 , 5036, (1984) 摘要
安全信息
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 94 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EJCTEA European Journal of Cancer Part A. (Pergamon Press, c/o Elsevier Science, 660 White Plains Rd., Tarrytown, NY 10591) V.28A(4/5)- 1992- Volume(issue)/page/year: 30A,525,1994
